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119 related items for PubMed ID: 29334326

  • 1. Predicting the dopamine D2 receptor occupancy of ropinirole in rats using positron emission tomography and pharmacokinetic-pharmacodynamic modeling.
    Huang C, Wang Z, Liu L, Liu X, Dong J, Xu Q, Zhang B, Miao L.
    Xenobiotica; 2019 Feb; 49(2):143-151. PubMed ID: 29334326
    [Abstract] [Full Text] [Related]

  • 2. Development of a population pharmacokinetic model to predict brain distribution and dopamine D2 receptor occupancy of raclopride in non-anesthetized rat.
    Wong YC, Ilkova T, van Wijk RC, Hartman R, de Lange ECM.
    Eur J Pharm Sci; 2018 Jan 01; 111():514-525. PubMed ID: 29106979
    [Abstract] [Full Text] [Related]

  • 3. Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study.
    Whone AL, Watts RL, Stoessl AJ, Davis M, Reske S, Nahmias C, Lang AE, Rascol O, Ribeiro MJ, Remy P, Poewe WH, Hauser RA, Brooks DJ, REAL-PET Study Group.
    Ann Neurol; 2003 Jul 01; 54(1):93-101. PubMed ID: 12838524
    [Abstract] [Full Text] [Related]

  • 4. Using pharmacokinetic-pharmacodynamic modelling as a tool for prediction of therapeutic effective plasma levels of antipsychotics.
    Olsen CK, Brennum LT, Kreilgaard M.
    Eur J Pharmacol; 2008 Apr 28; 584(2-3):318-27. PubMed ID: 18325493
    [Abstract] [Full Text] [Related]

  • 5. Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cells.
    Coldwell MC, Boyfield I, Brown T, Hagan JJ, Middlemiss DN.
    Br J Pharmacol; 1999 Aug 28; 127(7):1696-702. PubMed ID: 10455328
    [Abstract] [Full Text] [Related]

  • 6. Tolerance to peripheral, but not central, effects of ropinirole, a selective dopamine D2-like receptor agonist.
    Parker SG, Raval P, Yeulet S, Eden RJ.
    Eur J Pharmacol; 1994 Nov 14; 265(1-2):17-26. PubMed ID: 7883025
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and evaluation in rats of the dopamine D2/3 receptor agonist 18F-AMC20 as a potential radioligand for PET.
    Shalgunov V, van Wieringen JP, Janssen HM, Fransen PM, Dierckx RA, Michel MC, Booij J, Elsinga PH.
    J Nucl Med; 2015 Jan 14; 56(1):133-9. PubMed ID: 25476538
    [Abstract] [Full Text] [Related]

  • 8. Mechanism-based pharmacokinetic-pharmacodynamic modeling of the dopamine D2 receptor occupancy of olanzapine in rats.
    Johnson M, Kozielska M, Pilla Reddy V, Vermeulen A, Li C, Grimwood S, de Greef R, Groothuis GM, Danhof M, Proost JH.
    Pharm Res; 2011 Oct 14; 28(10):2490-504. PubMed ID: 21647790
    [Abstract] [Full Text] [Related]

  • 9. Sigma-1 and dopamine D2/D3 receptor occupancy of pridopidine in healthy volunteers and patients with Huntington disease: a [18F] fluspidine and [18F] fallypride PET study.
    Grachev ID, Meyer PM, Becker GA, Bronzel M, Marsteller D, Pastino G, Voges O, Rabinovich L, Knebel H, Zientek F, Rullmann M, Sattler B, Patt M, Gerhards T, Strauss M, Kluge A, Brust P, Savola JM, Gordon MF, Geva M, Hesse S, Barthel H, Hayden MR, Sabri O.
    Eur J Nucl Med Mol Imaging; 2021 Apr 14; 48(4):1103-1115. PubMed ID: 32995944
    [Abstract] [Full Text] [Related]

  • 10. Binding characteristics and sensitivity to endogenous dopamine of [11C]-(+)-PHNO, a new agonist radiotracer for imaging the high-affinity state of D2 receptors in vivo using positron emission tomography.
    Ginovart N, Galineau L, Willeit M, Mizrahi R, Bloomfield PM, Seeman P, Houle S, Kapur S, Wilson AA.
    J Neurochem; 2006 May 14; 97(4):1089-103. PubMed ID: 16606355
    [Abstract] [Full Text] [Related]

  • 11. Imaging Agonist-Induced D2/D3 Receptor Desensitization and Internalization In Vivo with PET/fMRI.
    Sander CY, Hooker JM, Catana C, Rosen BR, Mandeville JB.
    Neuropsychopharmacology; 2016 Apr 14; 41(5):1427-36. PubMed ID: 26388148
    [Abstract] [Full Text] [Related]

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  • 13. D2 receptor occupancy in conscious rat brain is not significantly distinguished with [3H]-MNPA, [3H]-(+)-PHNO, and [3H]-raclopride.
    Peng T, Zysk J, Dorff P, Elmore CS, Ström P, Malmquist J, Ding M, Tuke D, Werkheiser J, Widzowski D, Mrzljak L, Maier D.
    Synapse; 2010 Aug 14; 64(8):624-33. PubMed ID: 20340171
    [Abstract] [Full Text] [Related]

  • 14. A positron emission tomography (PET) study of cerebral dopamine D2 and serotonine 5-HT2A receptor occupancy in patients treated with cyamemazine (Tercian).
    Hodé Y, Reimold M, Demazières A, Reischl G, Bayle F, Nuss P, Hameg A, Dib M, Macher JP.
    Psychopharmacology (Berl); 2005 Jul 14; 180(2):377-84. PubMed ID: 15948013
    [Abstract] [Full Text] [Related]

  • 15. Occupancy of pramipexole (Sifrol) at cerebral dopamine D2/3 receptors in Parkinson's disease patients.
    Deutschländer A, la Fougère C, Boetzel K, Albert NL, Gildehaus FJ, Bartenstein P, Xiong G, Cumming P.
    Neuroimage Clin; 2016 Jul 14; 12():41-6. PubMed ID: 27408789
    [Abstract] [Full Text] [Related]

  • 16. Overexpression of D2/D3 receptors increases efficacy of ropinirole in chronically 6-OHDA-lesioned Parkinsonian rats.
    Matsukawa N, Maki M, Yasuhara T, Hara K, Yu G, Xu L, Kim KM, Morgan JC, Sethi KD, Borlongan CV.
    Brain Res; 2007 Jul 30; 1160():113-23. PubMed ID: 17573046
    [Abstract] [Full Text] [Related]

  • 17. Pharmacokinetics of sertindole and its metabolite dehydrosertindole in rats and characterization of their comparative pharmacodynamics based on in vivo D2 receptor occupancy and behavioural conditioned avoidance response.
    Bundgaard C, Larsen F, Kreilgaard M, Brennum LT, Olsen CK.
    Biopharm Drug Dispos; 2009 May 30; 30(4):209-20. PubMed ID: 19475539
    [Abstract] [Full Text] [Related]

  • 18. Formulation of intranasal mucoadhesive temperature-mediated in situ gel containing ropinirole and evaluation of brain targeting efficiency in rats.
    Khan S, Patil K, Bobade N, Yeole P, Gaikwad R.
    J Drug Target; 2010 Apr 30; 18(3):223-34. PubMed ID: 20030503
    [Abstract] [Full Text] [Related]

  • 19. Predicting brain occupancy from plasma levels using PET: superiority of combining pharmacokinetics with pharmacodynamics while modeling the relationship.
    Kim E, Howes OD, Kim BH, Jeong JM, Lee JS, Jang IJ, Shin SG, Turkheimer FE, Kapur S, Kwon JS.
    J Cereb Blood Flow Metab; 2012 Apr 30; 32(4):759-68. PubMed ID: 22186667
    [Abstract] [Full Text] [Related]

  • 20. Dopamine D3 receptor binding of (18)F-fallypride: Evaluation using in vitro and in vivo PET imaging studies.
    Mukherjee J, Constantinescu CC, Hoang AT, Jerjian T, Majji D, Pan ML.
    Synapse; 2015 Dec 30; 69(12):577-91. PubMed ID: 26422464
    [Abstract] [Full Text] [Related]

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