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Journal Abstract Search

227 related items for PubMed ID: 29373269

  • 1. Surrogating and redirection of pyrazolo[1,5-a]pyrimidin-7(4H)-one core, a novel class of potent and selective DPP-4 inhibitors.
    Deng X, Shen J, Zhu H, Xiao J, Sun R, Xie F, Lam C, Wang J, Qiao Y, Tavallaie MS, Hu Y, Du Y, Li J, Fu L, Jiang F.
    Bioorg Med Chem; 2018 Feb 15; 26(4):903-912. PubMed ID: 29373269
    [Abstract] [Full Text] [Related]

  • 2. Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors.
    Shen J, Deng X, Sun R, Tavallaie MS, Wang J, Cai Q, Lam C, Lei S, Fu L, Jiang F.
    Eur J Med Chem; 2020 Dec 15; 208():112850. PubMed ID: 32987315
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and biological evaluation of novel pyrazolo-pyrimidinones as DPP-IV inhibitors in diabetes.
    Sagar SR, Agarwal JK, Pandya DH, Dash RP, Nivsarkar M, Vasu KK.
    Bioorg Med Chem Lett; 2015 Oct 15; 25(20):4428-33. PubMed ID: 26372650
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors.
    Patel BD, Bhadada SV, Ghate MD.
    Bioorg Chem; 2017 Jun 15; 72():345-358. PubMed ID: 28302310
    [Abstract] [Full Text] [Related]

  • 5. Discovery of triazole-based uracil derivatives bearing amide moieties as novel dipeptidyl peptidase-IV inhibitors.
    Deng X, Han L, Zhou J, Zhang H, Li Q.
    Bioorg Chem; 2017 Dec 15; 75():357-367. PubMed ID: 29096096
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological evaluation of novel pyrimidinedione derivatives as DPP-4 inhibitors.
    Li N, Wang LJ, Jiang B, Guo SJ, Li XQ, Chen XC, Luo J, Li C, Wang Y, Shi DY.
    Bioorg Med Chem Lett; 2018 Jul 01; 28(12):2131-2135. PubMed ID: 29773502
    [Abstract] [Full Text] [Related]

  • 7. Design, Synthesis and Biological Evaluation of Imidazo[1,2-a]pyridine Derivatives as Novel DPP-4 Inhibitors.
    Li Q, Zhou M, Han L, Cao Q, Wang X, Zhao L, Zhou J, Zhang H.
    Chem Biol Drug Des; 2015 Oct 01; 86(4):849-56. PubMed ID: 25787859
    [Abstract] [Full Text] [Related]

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  • 10. Finding a Potential Dipeptidyl Peptidase-4 (DPP-4) Inhibitor for Type-2 Diabetes Treatment Based on Molecular Docking, Pharmacophore Generation, and Molecular Dynamics Simulation.
    Meduru H, Wang YT, Tsai JJ, Chen YC.
    Int J Mol Sci; 2016 Jun 13; 17(6):. PubMed ID: 27304951
    [Abstract] [Full Text] [Related]

  • 11. Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-ylcarbonyl]thiazolidine): a highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
    Yoshida T, Akahoshi F, Sakashita H, Kitajima H, Nakamura M, Sonda S, Takeuchi M, Tanaka Y, Ueda N, Sekiguchi S, Ishige T, Shima K, Nabeno M, Abe Y, Anabuki J, Soejima A, Yoshida K, Takashina Y, Ishii S, Kiuchi S, Fukuda S, Tsutsumiuchi R, Kosaka K, Murozono T, Nakamaru Y, Utsumi H, Masutomi N, Kishida H, Miyaguchi I, Hayashi Y.
    Bioorg Med Chem; 2012 Oct 01; 20(19):5705-19. PubMed ID: 22959556
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, evaluation and molecular docking of thiazolopyrimidine derivatives as dipeptidyl peptidase IV inhibitors.
    Sharma M, Gupta M, Singh D, Kumar M, Kaur P.
    Chem Biol Drug Des; 2012 Dec 01; 80(6):918-28. PubMed ID: 22943413
    [Abstract] [Full Text] [Related]

  • 13. Discovery of novel xanthine compounds targeting DPP-IV and GPR119 as anti-diabetic agents.
    Li G, Huan Y, Yuan B, Wang J, Jiang Q, Lin Z, Shen Z, Huang H.
    Eur J Med Chem; 2016 Nov 29; 124():103-116. PubMed ID: 27560285
    [Abstract] [Full Text] [Related]

  • 14. Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    Li N, Wang LJ, Jiang B, Li XQ, Guo CL, Guo SJ, Shi DY.
    Eur J Med Chem; 2018 May 10; 151():145-157. PubMed ID: 29609120
    [Abstract] [Full Text] [Related]

  • 15. Design and synthesis of quinazoline-3,4-(4H)-diamine endowed with thiazoline moiety as new class for DPP-4 and DPPH inhibitor.
    Ali Z, Akhtar MJ, Haider MR, Khan AA, Siddiqui AA, Yar MS.
    Bioorg Chem; 2017 Apr 10; 71():181-191. PubMed ID: 28215601
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological evaluation of triazole based uracil derivatives as novel DPP-4 inhibitors.
    Li Q, Han L, Zhang B, Zhou J, Zhang H.
    Org Biomol Chem; 2016 Oct 12; 14(40):9598-9611. PubMed ID: 27714283
    [Abstract] [Full Text] [Related]

  • 17. Novel DPP-4 inhibitors against diabetes.
    Liu Y, Hu Y.
    Future Med Chem; 2014 May 12; 6(7):793-808. PubMed ID: 24941873
    [Abstract] [Full Text] [Related]

  • 18. RBx-0597, a potent, selective and slow-binding inhibitor of dipeptidyl peptidase-IV for the treatment of type 2 diabetes.
    Singh S, Roy S, Sethi S, Benjamin B, Sundaram S, Khanna V, Kandalkar SR, Pal C, Kant R, Patra AK, Rayasam G, Mittra S, Saini KS, Paliwal J, Chugh A, Ahmed S, Sattigeri J, Cliff I, Ray A, Bansal VS, Bhatnagar PK, Davis JA.
    Eur J Pharmacol; 2011 Feb 10; 652(1-3):157-63. PubMed ID: 20540938
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological evaluation of pyrrolidine-2-carbonitrile and 4-fluoropyrrolidine-2-carbonitrile derivatives as dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes.
    Wang J, Feng Y, Ji X, Deng G, Leng Y, Liu H.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7418-29. PubMed ID: 24153396
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, and pharmacological evaluation of highly potent and selective dipeptidyl peptidase-4 inhibitors.
    Jiang T, Zhou Y, Zhu J, Chen Z, Sun P, Zhang Q, Wang Z, Shao Q, Jiang X, Li B, Wang H, Zhu W, Shen J.
    Arch Pharm (Weinheim); 2015 Jun 01; 348(6):399-407. PubMed ID: 25871012
    [Abstract] [Full Text] [Related]

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