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PUBMED FOR HANDHELDS

Journal Abstract Search


122 related items for PubMed ID: 29439902

  • 1. MF-8, a novel promising arylpiperazine-hydantoin based 5-HT7 receptor antagonist: In vitro drug-likeness studies and in vivo pharmacological evaluation.
    Latacz G, Lubelska A, Jastrzębska-Więsek M, Partyka A, Kucwaj-Brysz K, Wesołowska A, Kieć-Kononowicz K, Handzlik J.
    Bioorg Med Chem Lett; 2018 Mar 01; 28(5):878-883. PubMed ID: 29439902
    [Abstract] [Full Text] [Related]

  • 2. Computer-aided insights into receptor-ligand interaction for novel 5-arylhydantoin derivatives as serotonin 5-HT7 receptor agents with antidepressant activity.
    Kucwaj-Brysz K, Kurczab R, Jastrzębska-Więsek M, Żesławska E, Satała G, Nitek W, Partyka A, Siwek A, Jankowska A, Wesołowska A, Kieć-Kononowicz K, Handzlik J.
    Eur J Med Chem; 2018 Mar 10; 147():102-114. PubMed ID: 29425815
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  • 3. In the search for a lead structure among series of potent and selective hydantoin 5-HT7 R agents: The drug-likeness in vitro study.
    Latacz G, Lubelska A, Jastrzębska-Więsek M, Partyka A, Sobiło A, Olejarz A, Kucwaj-Brysz K, Satała G, Bojarski AJ, Wesołowska A, Kieć-Kononowicz K, Handzlik J.
    Chem Biol Drug Des; 2017 Dec 10; 90(6):1295-1306. PubMed ID: 28886235
    [Abstract] [Full Text] [Related]

  • 4. Rational design in search for 5-phenylhydantoin selective 5-HT7R antagonists. Molecular modeling, synthesis and biological evaluation.
    Kucwaj-Brysz K, Warszycki D, Podlewska S, Witek J, Witek K, González Izquierdo A, Satała G, Loza MI, Lubelska A, Latacz G, Bojarski AJ, Castro M, Kieć-Kononowicz K, Handzlik J.
    Eur J Med Chem; 2016 Apr 13; 112():258-269. PubMed ID: 26900658
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  • 6. The relationship between stereochemical and both, pharmacological and ADME-Tox, properties of the potent hydantoin 5-HT7R antagonist MF-8.
    Kucwaj-Brysz K, Latacz G, Podlewska S, Żesławska E, Handzlik J, Lubelska A, Satała G, Nitek W, Handzlik J.
    Bioorg Chem; 2021 Jan 13; 106():104466. PubMed ID: 33246603
    [Abstract] [Full Text] [Related]

  • 7. Aryl biphenyl-3-ylmethylpiperazines as 5-HT7 receptor antagonists.
    Kim J, Kim Y, Tae J, Yeom M, Moon B, Huang XP, Roth BL, Lee K, Rhim H, Choo IH, Chong Y, Keum G, Nam G, Choo H.
    ChemMedChem; 2013 Nov 13; 8(11):1855-64. PubMed ID: 24039134
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  • 9. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M, Berardi F, Colabufo NA, Contino M, Lacivita E, Niso M, Perrone R, Tortorella V.
    J Med Chem; 2004 Dec 16; 47(26):6616-24. PubMed ID: 15588097
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  • 10. NEW SPIROHYDANTOIN DERIVATIVES - SYNTHESIS, PHARMACOLOGICAL EVALUATION, AND MOLECULAR MODELING STUDY.
    Czopek A, Zagorska A, Kolaczkowski M, Bucki A, Gryzlo B, Rychtyk J, Pawlowsk M, Siwek A, Satala G, Bojarski A, Kubacka M, Filipek B.
    Acta Pol Pharm; 2016 Nov 16; 73(6):1545-1554. PubMed ID: 29634109
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  • 11. Novel spirohydantoin derivative as a potent multireceptor-active antipsychotic and antidepressant agent.
    Czopek A, Kołaczkowski M, Bucki A, Byrtus H, Pawłowski M, Kazek G, Bojarski AJ, Piaskowska A, Kalinowska-Tłuścik J, Partyka A, Wesołowska A.
    Bioorg Med Chem; 2015 Jul 01; 23(13):3436-47. PubMed ID: 25936259
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  • 12. Synthesis and structure-activity relationships of new carbonyl guanidine derivatives as novel dual 5-HT2B and 5-HT7 receptor antagonists.
    Moritomo A, Yamada H, Watanabe T, Itahana H, Akuzawa S, Okada M, Ohta M.
    Bioorg Med Chem; 2013 Dec 15; 21(24):7841-52. PubMed ID: 24189186
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  • 13. Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain.
    Shimoda Y, Yui J, Xie L, Fujinaga M, Yamasaki T, Ogawa M, Nengaki N, Kumata K, Hatori A, Kawamura K, Zhang MR.
    Bioorg Med Chem; 2013 Sep 01; 21(17):5316-22. PubMed ID: 23830697
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  • 14. Aminoalkyl Derivatives of 8-Alkoxypurine-2,6-diones: Multifunctional 5-HT1A /5-HT7 Receptor Ligands and PDE Inhibitors with Antidepressant Activity.
    Chłoń-Rzepa G, Zagórska A, Żmudzki P, Bucki A, Kołaczkowski M, Partyka A, Wesołowska A, Kazek G, Głuch-Lutwin M, Siwek A, Starowicz G, Pawłowski M.
    Arch Pharm (Weinheim); 2016 Dec 01; 349(12):889-903. PubMed ID: 27869315
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  • 15. The impact of the halogen bonding on D2 and 5-HT1A/5-HT7 receptor activity of azinesulfonamides of 4-[(2-ethyl)piperidinyl-1-yl]phenylpiperazines with antipsychotic and antidepressant properties.
    Partyka A, Kurczab R, Canale V, Satała G, Marciniec K, Pasierb A, Jastrzębska-Więsek M, Pawłowski M, Wesołowska A, Bojarski AJ, Zajdel P.
    Bioorg Med Chem; 2017 Jul 15; 25(14):3638-3648. PubMed ID: 28529043
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  • 16. Single Administration of HBK-15-a Triple 5-HT1A, 5-HT7, and 5-HT3 Receptor Antagonist-Reverses Depressive-Like Behaviors in Mouse Model of Depression Induced by Corticosterone.
    Pytka K, Głuch-Lutwin M, Kotańska M, Waszkielewicz A, Kij A, Walczak M.
    Mol Neurobiol; 2018 May 15; 55(5):3931-3945. PubMed ID: 28550529
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  • 18. Novel anilide and benzylamide derivatives of arylpiperazinylalkanoic acids as 5-HT1A/5-HT7 receptor antagonists and phosphodiesterase 4/7 inhibitors with procognitive and antidepressant activity.
    Jankowska A, Satała G, Kołaczkowski M, Bucki A, Głuch-Lutwin M, Świerczek A, Pociecha K, Partyka A, Jastrzębska-Więsek M, Lubelska A, Latacz G, Gawalska A, Bojarski AJ, Wyska E, Chłoń-Rzepa G.
    Eur J Med Chem; 2020 Sep 01; 201():112437. PubMed ID: 32673902
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