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Journal Abstract Search

186 related items for PubMed ID: 29477480

  • 1. Dehydroevodiamine and hortiamine, alkaloids from the traditional Chinese herbal drug Evodia rutaecarpa, are IKr blockers with proarrhythmic effects in vitro and in vivo.
    Baburin I, Varkevisser R, Schramm A, Saxena P, Beyl S, Szkokan P, Linder T, Stary-Weinzinger A, van der Heyden MAG, Houtman M, Takanari H, Jonsson M, Beekman JHD, Hamburger M, Vos MA, Hering S.
    Pharmacol Res; 2018 May; 131():150-163. PubMed ID: 29477480
    [Abstract] [Full Text] [Related]

  • 2. Assay for evaluation of proarrhythmic effects of herbal products: Case study with 12 Evodia preparations.
    Baltov B, Beyl S, Baburin I, Reinhardt J, Szkokan P, Garifulina A, Timin E, Kraushaar U, Potterat O, Hamburger M, Kügler P, Hering S.
    Toxicol Rep; 2023 May; 10():589-599. PubMed ID: 37213814
    [Abstract] [Full Text] [Related]

  • 3. Gram-scale purification of dehydroevodiamine from Evodia rutaecarpa fruits, and a procedure for selective removal of quaternary indoloquinazoline alkaloids from Evodia extracts.
    Schramm A, Hamburger M.
    Fitoterapia; 2014 Apr; 94():127-33. PubMed ID: 24561006
    [Abstract] [Full Text] [Related]

  • 4. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C, Pierre-Valentin J, Pollard C, Standen N, Mitcheson J, Alexander P, Thong B.
    J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
    [Abstract] [Full Text] [Related]

  • 5. Does terfenadine-induced ventricular tachycardia/fibrillation directly relate to its QT prolongation and Torsades de Pointes?
    Lu HR, Hermans AN, Gallacher DJ.
    Br J Pharmacol; 2012 Jun; 166(4):1490-502. PubMed ID: 22300168
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  • 7. Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel.
    Park MH, Lee SH, Chu DH, Won KH, Choi BH, Choe H, Jo SH.
    J Pharmacol Sci; 2013 Sep 20; 123(1):67-77. PubMed ID: 24005046
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  • 8. Istaroxime, a positive inotropic agent devoid of proarrhythmic properties in sensitive chronic atrioventricular block dogs.
    Bossu A, Kostense A, Beekman HDM, Houtman MJC, van der Heyden MAG, Vos MA.
    Pharmacol Res; 2018 Jul 20; 133():132-140. PubMed ID: 29753687
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  • 10. Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Mirams GR, Cui Y, Sher A, Fink M, Cooper J, Heath BM, McMahon NC, Gavaghan DJ, Noble D.
    Cardiovasc Res; 2011 Jul 01; 91(1):53-61. PubMed ID: 21300721
    [Abstract] [Full Text] [Related]

  • 11. Chronic amiodarone evokes no torsade de pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome.
    van Opstal JM, Schoenmakers M, Verduyn SC, de Groot SH, Leunissen JD, van Der Hulst FF, Molenschot MM, Wellens HJ, Vos MA.
    Circulation; 2001 Nov 27; 104(22):2722-7. PubMed ID: 11723026
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  • 13. A new biomarker--index of cardiac electrophysiological balance (iCEB)--plays an important role in drug-induced cardiac arrhythmias: beyond QT-prolongation and Torsades de Pointes (TdPs).
    Lu HR, Yan GX, Gallacher DJ.
    J Pharmacol Toxicol Methods; 2013 Nov 27; 68(2):250-259. PubMed ID: 23337247
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  • 15. Vernakalant is devoid of proarrhythmic effects in the complete AV block dog model.
    Varkevisser R, van der Heyden MA, Tieland RG, Beekman JD, Vos MA.
    Eur J Pharmacol; 2013 Nov 15; 720(1-3):49-54. PubMed ID: 24211677
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  • 17. Transmural dispersion of repolarization as a preclinical marker of drug-induced proarrhythmia.
    Said TH, Wilson LD, Jeyaraj D, Fossa AA, Rosenbaum DS.
    J Cardiovasc Pharmacol; 2012 Aug 15; 60(2):165-71. PubMed ID: 22561361
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  • 19. Selective late sodium current inhibitor GS-458967 suppresses Torsades de Pointes by mostly affecting perpetuation but not initiation of the arrhythmia.
    Bossu A, Houtman MJC, Meijborg VMF, Varkevisser R, Beekman HDM, Dunnink A, de Bakker JMT, Mollova N, Rajamani S, Belardinelli L, van der Heyden MAG, Vos MA.
    Br J Pharmacol; 2018 Jun 15; 175(12):2470-2482. PubMed ID: 29582428
    [Abstract] [Full Text] [Related]

  • 20. Intracellular Mechanism of Rosuvastatin-Induced Decrease in Mature hERG Protein Expression on Membrane.
    Feng PF, Zhang B, Zhao L, Fang Q, Liu Y, Wang JN, Xu XQ, Xue H, Li Y, Yan CC, Zhao X, Li BX.
    Mol Pharm; 2019 Apr 01; 16(4):1477-1488. PubMed ID: 30807184
    [Abstract] [Full Text] [Related]

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