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Journal Abstract Search

130 related items for PubMed ID: 29478239

  • 1. A Phase I Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of the Novel Dopamine D1 Receptor Partial Agonist, PF-06669571, in Subjects with Idiopathic Parkinson's Disease.
    Gurrell R, Duvvuri S, Sun P, DeMartinis N.
    Clin Drug Investig; 2018 Jun; 38(6):509-517. PubMed ID: 29478239
    [Abstract] [Full Text] [Related]

  • 2. The D1/D5 Dopamine Partial Agonist PF-06412562 in Advanced-Stage Parkinson's Disease: A Feasibility Study.
    Huang X, Lewis MM, Van Scoy LJ, De Jesus S, Eslinger PJ, Arnold AC, Miller AJ, Fernandez-Mendoza J, Snyder B, Harrington W, Kong L, Wang X, Sun D, Delnomdedieu M, Duvvuri S, Mahoney SE, Gray DL, Mailman RB.
    J Parkinsons Dis; 2020 Jun; 10(4):1515-1527. PubMed ID: 32986682
    [Abstract] [Full Text] [Related]

  • 3. Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study.
    Svenningsson P, Rosenblad C, Af Edholm Arvidsson K, Wictorin K, Keywood C, Shankar B, Lowe DA, Björklund A, Widner H.
    Brain; 2015 Apr; 138(Pt 4):963-73. PubMed ID: 25669730
    [Abstract] [Full Text] [Related]

  • 4. Phase 1 Parkinson's Disease Studies Show the Dopamine D1/D5 Agonist PF-06649751 is Safe and Well Tolerated.
    Sohur US, Gray DL, Duvvuri S, Zhang Y, Thayer K, Feng G.
    Neurol Ther; 2018 Dec; 7(2):307-319. PubMed ID: 30361858
    [Abstract] [Full Text] [Related]

  • 5. Evaluation of D1/D5 Partial Agonist PF-06412562 in Parkinson's Disease following Oral Administration.
    Papapetropoulos S, Liu W, Duvvuri S, Thayer K, Gray DL.
    Neurodegener Dis; 2018 Dec; 18(5-6):262-269. PubMed ID: 30453303
    [Abstract] [Full Text] [Related]

  • 6. A Neurofunctional Domains Approach to Evaluate D1/D5 Dopamine Receptor Partial Agonism on Cognition and Motivation in Healthy Volunteers With Low Working Memory Capacity.
    Balice-Gordon R, Honey GD, Chatham C, Arce E, Duvvuri S, Naylor MG, Liu W, Xie Z, DeMartinis N, Harel BT, Braley GH, Kozak R, Park L, Gray DL.
    Int J Neuropsychopharmacol; 2020 May 27; 23(5):287-299. PubMed ID: 32055822
    [Abstract] [Full Text] [Related]

  • 7. A novel approach to evaluate the pharmacodynamics of a selective dopamine D1/D5 receptor partial agonist (PF-06412562) in patients with stable schizophrenia.
    Arce E, Balice-Gordon R, Duvvuri S, Naylor M, Xie Z, Harel B, Kozak R, Gray DL, DeMartinis N.
    J Psychopharmacol; 2019 Oct 27; 33(10):1237-1247. PubMed ID: 31264510
    [Abstract] [Full Text] [Related]

  • 8. Rotigotine transdermal system as add-on to oral dopamine agonist in advanced Parkinson's disease: an open-label study.
    Kim JM, Chung SJ, Kim JW, Jeon BS, Singh P, Thierfelder S, Ikeda J, Bauer L, Asia Pacific Rotigotine Add-on Study Group.
    BMC Neurol; 2015 Feb 28; 15():17. PubMed ID: 25879416
    [Abstract] [Full Text] [Related]

  • 9. Effects of the full dopamine D1 receptor agonist dihydrexidine in Parkinson's disease.
    Blanchet PJ, Fang J, Gillespie M, Sabounjian L, Locke KW, Gammans R, Mouradian MM, Chase TN.
    Clin Neuropharmacol; 1998 Feb 28; 21(6):339-43. PubMed ID: 9844789
    [Abstract] [Full Text] [Related]

  • 10. The long-acting dopamine receptor agonist cabergoline in early Parkinson's disease: final results of a 5-year, double-blind, levodopa-controlled study.
    Bracco F, Battaglia A, Chouza C, Dupont E, Gershanik O, Marti Masso JF, Montastruc JL, PKDS009 Study Group.
    CNS Drugs; 2004 Feb 28; 18(11):733-46. PubMed ID: 15330687
    [Abstract] [Full Text] [Related]

  • 11. PF-06649751 efficacy and safety in early Parkinson's disease: a randomized, placebo-controlled trial.
    Riesenberg R, Werth J, Zhang Y, Duvvuri S, Gray D.
    Ther Adv Neurol Disord; 2020 Feb 28; 13():1756286420911296. PubMed ID: 32201505
    [Abstract] [Full Text] [Related]

  • 12. Concurrent administration of donepezil HCl and levodopa/carbidopa in patients with Parkinson's disease: assessment of pharmacokinetic changes and safety following multiple oral doses.
    Okereke CS, Kirby L, Kumar D, Cullen EI, Pratt RD, Hahne WA.
    Br J Clin Pharmacol; 2004 Nov 28; 58 Suppl 1(Suppl 1):41-9. PubMed ID: 15496222
    [Abstract] [Full Text] [Related]

  • 13. Pharmacodynamics of levodopa coadministered with apomorphine in parkinsonian patients with end-of-dose motor fluctuations.
    Baas H, Harder S, Bürklin F, Demisch L, Fischer PA.
    Clin Neuropharmacol; 1998 Nov 28; 21(2):86-92. PubMed ID: 9579293
    [Abstract] [Full Text] [Related]

  • 14. AFQ056 in Parkinson patients with levodopa-induced dyskinesia: 13-week, randomized, dose-finding study.
    Stocchi F, Rascol O, Destee A, Hattori N, Hauser RA, Lang AE, Poewe W, Stacy M, Tolosa E, Gao H, Nagel J, Merschhemke M, Graf A, Kenney C, Trenkwalder C.
    Mov Disord; 2013 Nov 28; 28(13):1838-46. PubMed ID: 23853029
    [Abstract] [Full Text] [Related]

  • 15. Effects of rotigotine transdermal patch in patients with Parkinson's disease presenting with non-motor symptoms - results of a double-blind, randomized, placebo-controlled trial.
    Antonini A, Bauer L, Dohin E, Oertel WH, Rascol O, Reichmann H, Schmid M, Singh P, Tolosa E, Chaudhuri KR.
    Eur J Neurol; 2015 Oct 28; 22(10):1400-7. PubMed ID: 26095948
    [Abstract] [Full Text] [Related]

  • 16. Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial.
    Barone P, Poewe W, Albrecht S, Debieuvre C, Massey D, Rascol O, Tolosa E, Weintraub D.
    Lancet Neurol; 2010 Jun 28; 9(6):573-80. PubMed ID: 20452823
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