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Journal Abstract Search

356 related items for PubMed ID: 29487132

  • 1. The dopamine D2 receptor can directly recruit and activate GRK2 without G protein activation.
    Pack TF, Orlen MI, Ray C, Peterson SM, Caron MG.
    J Biol Chem; 2018 Apr 20; 293(16):6161-6171. PubMed ID: 29487132
    [Abstract] [Full Text] [Related]

  • 2. Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity.
    Peterson SM, Pack TF, Caron MG.
    PLoS One; 2015 Apr 20; 10(10):e0141637. PubMed ID: 26516769
    [Abstract] [Full Text] [Related]

  • 3. Ubiquitination of GRK2 Is Required for the β-Arrestin-Biased Signaling Pathway of Dopamine D2 Receptors to Activate ERK Kinases.
    Liu H, Ma H, Zeng X, Wu C, Acharya S, Sudan SK, Zhang X.
    Int J Mol Sci; 2023 Jun 12; 24(12):. PubMed ID: 37373182
    [Abstract] [Full Text] [Related]

  • 4. Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor.
    Peterson SM, Pack TF, Wilkins AD, Urs NM, Urban DJ, Bass CE, Lichtarge O, Caron MG.
    Proc Natl Acad Sci U S A; 2015 Jun 02; 112(22):7097-102. PubMed ID: 25964346
    [Abstract] [Full Text] [Related]

  • 5. RalA employs GRK2 and β-arrestins for the filamin A-mediated regulation of trafficking and signaling of dopamine D2 and D3 receptor.
    Zheng M, Zhang X, Sun N, Min C, Zhang X, Kim KM.
    Biochim Biophys Acta; 2016 Aug 02; 1863(8):2072-83. PubMed ID: 27188791
    [Abstract] [Full Text] [Related]

  • 6. G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation.
    Sánchez-Soto M, Boldizsar NM, Schardien KA, Madaras NS, Willette BKA, Inbody LR, Dasaro C, Moritz AE, Drube J, Haider RS, Free RB, Hoffman C, Sibley DR.
    Biomolecules; 2023 Oct 20; 13(10):. PubMed ID: 37892234
    [Abstract] [Full Text] [Related]

  • 7. A novel molecular mechanism responsible for phosphorylation-independent desensitization of G protein-coupled receptors exemplified by the dopamine D3 receptor.
    Zheng M, Zhang X, Sun N, Min X, Acharya S, Kim KM.
    Biochem Biophys Res Commun; 2020 Jul 30; 528(3):432-439. PubMed ID: 32505358
    [Abstract] [Full Text] [Related]

  • 8. GRK2-mediated receptor phosphorylation and Mdm2-mediated β-arrestin2 ubiquitination drive clathrin-mediated endocytosis of G protein-coupled receptors.
    Zhang X, Zheng M, Kim KM.
    Biochem Biophys Res Commun; 2020 Dec 10; 533(3):383-390. PubMed ID: 32962859
    [Abstract] [Full Text] [Related]

  • 9. Selective recruitment of G protein-coupled receptor kinases (GRKs) controls signaling of the insulin-like growth factor 1 receptor.
    Zheng H, Worrall C, Shen H, Issad T, Seregard S, Girnita A, Girnita L.
    Proc Natl Acad Sci U S A; 2012 May 01; 109(18):7055-60. PubMed ID: 22509025
    [Abstract] [Full Text] [Related]

  • 10. Differential Involvement of ACKR3 C-Tail in β-Arrestin Recruitment, Trafficking and Internalization.
    Zarca A, Perez C, van den Bor J, Bebelman JP, Heuninck J, de Jonker RJF, Durroux T, Vischer HF, Siderius M, Smit MJ.
    Cells; 2021 Mar 11; 10(3):. PubMed ID: 33799570
    [Abstract] [Full Text] [Related]

  • 11. A novel molecular mechanism involved in the crosstalks between homologous and PKC-mediated heterologous regulatory pathway of dopamine D2 receptor.
    Zhang X, Min X, Zhu A, Kim KM.
    Biochem Pharmacol; 2020 Apr 11; 174():113791. PubMed ID: 31917245
    [Abstract] [Full Text] [Related]

  • 12. Antipsychotic-Like Efficacy of Dopamine D2 Receptor-Biased Ligands is Dependent on Adenosine A2A Receptor Expression.
    Sahlholm K, Gómez-Soler M, Valle-León M, López-Cano M, Taura JJ, Ciruela F, Fernández-Dueñas V.
    Mol Neurobiol; 2018 Jun 11; 55(6):4952-4958. PubMed ID: 28779351
    [Abstract] [Full Text] [Related]

  • 13. Anaplastic Lymphoma Kinase Regulates Internalization of the Dopamine D2 Receptor.
    He D, Lasek AW.
    Mol Pharmacol; 2020 Feb 11; 97(2):123-131. PubMed ID: 31734646
    [Abstract] [Full Text] [Related]

  • 14. Beta-arrestin2 as a competitor for GRK2 interaction with the GLP-1 receptor upon receptor activation.
    Jorgensen R, Norklit Roed S, Heding A, Elling CE.
    Pharmacology; 2011 Feb 11; 88(3-4):174-81. PubMed ID: 21952200
    [Abstract] [Full Text] [Related]

  • 15. Distinct cortical and striatal actions of a β-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties.
    Urs NM, Gee SM, Pack TF, McCorvy JD, Evron T, Snyder JC, Yang X, Rodriguiz RM, Borrelli E, Wetsel WC, Jin J, Roth BL, O'Donnell P, Caron MG.
    Proc Natl Acad Sci U S A; 2016 Dec 13; 113(50):E8178-E8186. PubMed ID: 27911814
    [Abstract] [Full Text] [Related]

  • 16. G protein-coupled receptor kinases (GRKs) orchestrate biased agonism at the β2-adrenergic receptor.
    Choi M, Staus DP, Wingler LM, Ahn S, Pani B, Capel WD, Lefkowitz RJ.
    Sci Signal; 2018 Aug 21; 11(544):. PubMed ID: 30131371
    [Abstract] [Full Text] [Related]

  • 17. Engineered D2R Variants Reveal the Balanced and Biased Contributions of G-Protein and β-Arrestin to Dopamine-Dependent Functions.
    Rose SJ, Pack TF, Peterson SM, Payne K, Borrelli E, Caron MG.
    Neuropsychopharmacology; 2018 Apr 21; 43(5):1164-1173. PubMed ID: 29068002
    [Abstract] [Full Text] [Related]

  • 18. GRK2-dependent desensitization downstream of G proteins.
    Jurado-Pueyo M, Campos PM, Mayor F, Murga C.
    J Recept Signal Transduct Res; 2008 Apr 21; 28(1-2):59-70. PubMed ID: 18437630
    [Abstract] [Full Text] [Related]

  • 19. Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D2 Receptor (D2R) Biased Agonism.
    Bonifazi A, Yano H, Ellenberger MP, Muller L, Kumar V, Zou MF, Cai NS, Guerrero AM, Woods AS, Shi L, Newman AH.
    J Med Chem; 2017 Apr 13; 60(7):2890-2907. PubMed ID: 28300398
    [Abstract] [Full Text] [Related]

  • 20. Mapping the putative G protein-coupled receptor (GPCR) docking site on GPCR kinase 2: insights from intact cell phosphorylation and recruitment assays.
    Beautrait A, Michalski KR, Lopez TS, Mannix KM, McDonald DJ, Cutter AR, Medina CB, Hebert AM, Francis CJ, Bouvier M, Tesmer JJ, Sterne-Marr R.
    J Biol Chem; 2014 Sep 05; 289(36):25262-75. PubMed ID: 25049229
    [Abstract] [Full Text] [Related]

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