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Journal Abstract Search

259 related items for PubMed ID: 2950200

  • 1. Activity of antifolates against Pneumocystis carinii dihydrofolate reductase and identification of a potent new agent.
    Allegra CJ, Kovacs JA, Drake JC, Swan JC, Chabner BA, Masur H.
    J Exp Med; 1987 Mar 01; 165(3):926-31. PubMed ID: 2950200
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  • 2. Evaluation of potent inhibitors of dihydrofolate reductase in a culture model for growth of Pneumocystis carinii.
    Bartlett MS, Shaw M, Navaran P, Smith JW, Queener SF.
    Antimicrob Agents Chemother; 1995 Nov 01; 39(11):2436-41. PubMed ID: 8585722
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  • 3. Inhibition of Pneumocystis dihydrofolate reductase by analogs of pyrimethamine, methotrexate and trimetrexate.
    Queener SF.
    J Protozool; 1991 Nov 01; 38(6):154S-157S. PubMed ID: 1840146
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  • 4. A phenotype conferring selective resistance to lipophilic antifolates in Chinese hamster ovary cells.
    Sharma RC, Assaraf YG, Schimke RT.
    Cancer Res; 1991 Jun 01; 51(11):2949-59. PubMed ID: 1674447
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  • 5. Lipophilic antifolates as agents against opportunistic infections. 1. Agents superior to trimetrexate and piritrexim against Toxoplasma gondii and Pneumocystis carinii in in vitro evaluations.
    Piper JR, Johnson CA, Krauth CA, Carter RL, Hosmer CA, Queener SF, Borotz SE, Pfefferkorn ER.
    J Med Chem; 1996 Mar 15; 39(6):1271-80. PubMed ID: 8632434
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  • 7. Expression and characterization of recombinant human-derived Pneumocystis carinii dihydrofolate reductase.
    Ma L, Kovacs JA.
    Antimicrob Agents Chemother; 2000 Nov 15; 44(11):3092-6. PubMed ID: 11036028
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  • 8. Biochemical pharmacology of the lipophilic antifolate, trimetrexate.
    Jackson RC, Fry DW, Boritzki TJ, Besserer JA, Leopold WR, Sloan BJ, Elslager EF.
    Adv Enzyme Regul; 1984 Nov 15; 22():187-206. PubMed ID: 6236675
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  • 12. Treatment of Pneumocystis carinii pneumonia with trimetrexate in acquired immunodeficiency syndrome (AIDS).
    Allegra CJ, Chabner BA, Tuazon CU, Ogata-Arakaki D, Baird B, Drake JC, Masur H.
    Semin Oncol; 1988 Apr 15; 15(2 Suppl 2):46-9. PubMed ID: 2966985
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  • 13. 2,4-Diamino-5-substituted-quinazolines as inhibitors of a human dihydrofolate reductase with a site-directed mutation at position 22 and of the dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii.
    Rosowsky A, Mota CE, Queener SF, Waltham M, Ercikan-Abali E, Bertino JR.
    J Med Chem; 1995 Mar 03; 38(5):745-52. PubMed ID: 7877140
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  • 14. Effect of direct suppression of thymidylate synthase at the 5,10-methylenetetrahydrofolate binding site on the interconversion of tetrahydrofolate cofactors to dihydrofolate by antifolates. Influence of degree of dihydrofolate reductase inhibition.
    Seither RL, Trent DF, Mikulecky DC, Rape TJ, Goldman ID.
    J Biol Chem; 1991 Mar 05; 266(7):4112-8. PubMed ID: 1825652
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  • 17. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
    Diddens H, Niethammer D, Jackson RC.
    Cancer Res; 1983 Nov 05; 43(11):5286-92. PubMed ID: 6225514
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