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551 related items for PubMed ID: 29510199

  • 1. Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways.
    Rodenak-Kladniew B, Castro A, Stärkel P, De Saeger C, García de Bravo M, Crespo R.
    Life Sci; 2018 Apr 15; 199():48-59. PubMed ID: 29510199
    [Abstract] [Full Text] [Related]

  • 2. 1,8-Cineole promotes G0/G1 cell cycle arrest and oxidative stress-induced senescence in HepG2 cells and sensitizes cells to anti-senescence drugs.
    Rodenak-Kladniew B, Castro A, Stärkel P, Galle M, Crespo R.
    Life Sci; 2020 Feb 15; 243():117271. PubMed ID: 31926243
    [Abstract] [Full Text] [Related]

  • 3. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Feb 15; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

  • 4. The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells.
    Li JP, Yang YX, Liu QL, Pan ST, He ZX, Zhang X, Yang T, Chen XW, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Feb 15; 9():1627-52. PubMed ID: 25834401
    [Abstract] [Full Text] [Related]

  • 5. Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway.
    Wang JR, Li TZ, Wang C, Li SM, Luo YH, Piao XJ, Feng YC, Zhang Y, Xu WT, Zhang Y, Zhang T, Wang SN, Xue H, Wang HX, Cao LK, Jin CH.
    Naunyn Schmiedebergs Arch Pharmacol; 2020 Oct 15; 393(10):1987-1999. PubMed ID: 31956937
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  • 6. Investigation of prunetrin induced G2/M cell cycle arrest and apoptosis via Akt/mTOR/MAPK pathways in hepatocellular carcinoma cells.
    Abusaliya A, Bhosale PB, Kim HH, Park MY, Jeong SH, Lee S, Kim GS.
    Biomed Pharmacother; 2024 May 15; 174():116483. PubMed ID: 38552440
    [Abstract] [Full Text] [Related]

  • 7. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 May 15; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 8. Pentoxifylline induces apoptosis of HepG2 cells by reducing reactive oxygen species production and activating the MAPK signaling.
    Wang Y, Dong L, Li J, Luo M, Shang B.
    Life Sci; 2017 Aug 15; 183():60-68. PubMed ID: 28583366
    [Abstract] [Full Text] [Related]

  • 9. Delicaflavone induces ROS-mediated apoptosis and inhibits PI3K/AKT/mTOR and Ras/MEK/Erk signaling pathways in colorectal cancer cells.
    Yao W, Lin Z, Shi P, Chen B, Wang G, Huang J, Sui Y, Liu Q, Li S, Lin X, Liu Q, Yao H.
    Biochem Pharmacol; 2020 Jan 15; 171():113680. PubMed ID: 31669234
    [Abstract] [Full Text] [Related]

  • 10. Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma.
    Guenther MK, Graab U, Fulda S.
    Cancer Lett; 2013 Sep 01; 337(2):200-9. PubMed ID: 23684925
    [Abstract] [Full Text] [Related]

  • 11. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways.
    Zhang L, Huo X, Liao Y, Yang F, Gao L, Cao L.
    Sci Rep; 2017 May 10; 7(1):1669. PubMed ID: 28490807
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of Autophagy Promotes Salinomycin-Induced Apoptosis via Reactive Oxygen Species-Mediated PI3K/AKT/mTOR and ERK/p38 MAPK-Dependent Signaling in Human Prostate Cancer Cells.
    Kim KY, Park KI, Kim SH, Yu SN, Park SG, Kim YW, Seo YK, Ma JY, Ahn SC.
    Int J Mol Sci; 2017 May 18; 18(5):. PubMed ID: 28524116
    [Abstract] [Full Text] [Related]

  • 13. β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular carcinoma.
    Zhang G, He J, Ye X, Zhu J, Hu X, Shen M, Ma Y, Mao Z, Song H, Chen F.
    Cell Death Dis; 2019 Mar 15; 10(4):255. PubMed ID: 30874538
    [Abstract] [Full Text] [Related]

  • 14. Aspafilioside B induces G2/M cell cycle arrest and apoptosis by up-regulating H-Ras and N-Ras via ERK and p38 MAPK signaling pathways in human hepatoma HepG2 cells.
    Liu W, Ning R, Chen RN, Huang XF, Dai QS, Hu JH, Wang YW, Wu LL, Xiong J, Hu G, Guo QL, Yang J, Wang H.
    Mol Carcinog; 2016 May 15; 55(5):440-57. PubMed ID: 25683703
    [Abstract] [Full Text] [Related]

  • 15. Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways.
    Liu J, Li Q, Liu Z, Lin L, Zhang X, Cao M, Jiang J.
    Oncol Rep; 2016 Jun 15; 35(6):3363-70. PubMed ID: 27004568
    [Abstract] [Full Text] [Related]

  • 16. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Pan SY, Chen XW, Zhou SF.
    Drug Des Devel Ther; 2015 Jun 15; 9():1293-318. PubMed ID: 25767376
    [Abstract] [Full Text] [Related]

  • 17. Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt.
    Deng LJ, Hu LP, Peng QL, Yang XL, Bai LL, Yiu A, Li Y, Tian HY, Ye WC, Zhang DM.
    Chem Biol Interact; 2014 Aug 05; 219():184-94. PubMed ID: 24954031
    [Abstract] [Full Text] [Related]

  • 18. Inhibitory effect of oleanolic acid on hepatocellular carcinoma via ERK-p53-mediated cell cycle arrest and mitochondrial-dependent apoptosis.
    Wang X, Bai H, Zhang X, Liu J, Cao P, Liao N, Zhang W, Wang Z, Hai C.
    Carcinogenesis; 2013 Jun 05; 34(6):1323-30. PubMed ID: 23404993
    [Abstract] [Full Text] [Related]

  • 19. MK-2206 induces cell cycle arrest and apoptosis in HepG2 cells and sensitizes TRAIL-mediated cell death.
    Jiao P, Zhou YS, Yang JX, Zhao YL, Liu QQ, Yuan C, Wang FZ.
    Mol Cell Biochem; 2013 Oct 05; 382(1-2):217-24. PubMed ID: 23797319
    [Abstract] [Full Text] [Related]

  • 20. Equol inhibits proliferation of human gastric carcinoma cells via modulating Akt pathway.
    Yang ZP, Zhao Y, Huang F, Chen J, Yao YH, Li J, Wu XN.
    World J Gastroenterol; 2015 Sep 28; 21(36):10385-99. PubMed ID: 26420965
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