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Journal Abstract Search

217 related items for PubMed ID: 29543771

  • 21. Synthesis and glycogen phosphorylase inhibitory activity of N-(beta-D-glucopyranosyl)amides possessing 1,4-benzodioxane moiety.
    Czakó Z, Juhász L, Kenéz A, Czifrák K, Somsák L, Docsa T, Gergely P, Antus S.
    Bioorg Med Chem; 2009 Sep 15; 17(18):6738-41. PubMed ID: 19703777
    [Abstract] [Full Text] [Related]

  • 22. N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.
    Nagy V, Felföldi N, Kónya B, Praly JP, Docsa T, Gergely P, Chrysina ED, Tiraidis C, Kosmopoulou MN, Alexacou KM, Konstantakaki M, Leonidas DD, Zographos SE, Oikonomakos NG, Kozmon S, Tvaroška I, Somsák L.
    Bioorg Med Chem; 2012 Mar 01; 20(5):1801-16. PubMed ID: 22325154
    [Abstract] [Full Text] [Related]

  • 23. Synthesis of N-(beta-D-glucopyranosyl)- and N-(2-acetamido-2-deoxy-beta-D-glucopyranosyl) amides as inhibitors of glycogen phosphorylase.
    Györgydeák Z, Hadady Z, Felföldi N, Krakomperger A, Nagy V, Tóth M, Brunyánszki A, Docsa T, Gergely P, Somsák L.
    Bioorg Med Chem; 2004 Sep 15; 12(18):4861-70. PubMed ID: 15336265
    [Abstract] [Full Text] [Related]

  • 24. Synthesis of new glycosyl biuret and urea derivatives as potential glycoenzyme inhibitors.
    Felföldi N, Tóth M, Chrysina ED, Charavgi MD, Alexacou KM, Somsák L.
    Carbohydr Res; 2010 Jan 26; 345(2):208-13. PubMed ID: 20004366
    [Abstract] [Full Text] [Related]

  • 25. Synthesis, Kinetic and Conformational Studies of 2-Substituted-5-(β-d-glucopyranosyl)-pyrimidin-4-ones as Potential Inhibitors of Glycogen Phosphorylase.
    Mavreas KF, Neofytos DD, Chrysina ED, Venturini A, Gimisis T.
    Molecules; 2020 Nov 22; 25(22):. PubMed ID: 33266408
    [Abstract] [Full Text] [Related]

  • 26. Glucopyranosylidene-spiro-iminothiazolidinone, a new bicyclic ring system: synthesis, derivatization, and evaluation for inhibition of glycogen phosphorylase by enzyme kinetic and crystallographic methods.
    Czifrák K, Páhi A, Deák S, Kiss-Szikszai A, Kövér KE, Docsa T, Gergely P, Alexacou KM, Papakonstantinou M, Leonidas DD, Zographos SE, Chrysina ED, Somsák L.
    Bioorg Med Chem; 2014 Aug 01; 22(15):4028-41. PubMed ID: 25009003
    [Abstract] [Full Text] [Related]

  • 27. The binding of β-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors.
    Alexacou KM, Tenchiu Deleanu AC, Chrysina ED, Charavgi MD, Kostas ID, Zographos SE, Oikonomakos NG, Leonidas DD.
    Bioorg Med Chem; 2010 Nov 15; 18(22):7911-22. PubMed ID: 20947361
    [Abstract] [Full Text] [Related]

  • 28. Assessment of synthetic methods for the preparation of N-beta-d-glucopyranosyl-N'-substituted ureas, -thioureas and related compounds.
    Somsák L, Felföldi N, Kónya B, Hüse C, Telepó K, Bokor E, Czifrák K.
    Carbohydr Res; 2008 Aug 11; 343(12):2083-93. PubMed ID: 18299124
    [Abstract] [Full Text] [Related]

  • 29. The architecture of hydrogen and sulfur σ-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design.
    Kyriakis E, Karra AG, Papaioannou O, Solovou T, Skamnaki VT, Liggri PGV, Zographos SE, Szennyes E, Bokor É, Kun S, Psarra AG, Somsák L, Leonidas DD.
    Bioorg Med Chem; 2020 Jan 01; 28(1):115196. PubMed ID: 31767404
    [Abstract] [Full Text] [Related]

  • 30. C-Glucopyranosyl-1,2,4-triazoles As New Potent Inhibitors of Glycogen Phosphorylase.
    Bokor E, Docsa T, Gergely P, Somsák L.
    ACS Med Chem Lett; 2013 Jul 11; 4(7):612-5. PubMed ID: 24900719
    [Abstract] [Full Text] [Related]

  • 31. Synthesis of some derivatives of C-(1-deoxy-1-N-substituted-D-glucopyranosyl)formic acid (D-gluco-hept-2-ulopyranosonic acid) as potential inhibitors of glycogen phosphorylase.
    Czifrák K, Kovács L, Kövér KE, Somsák L.
    Carbohydr Res; 2005 Oct 17; 340(14):2328-34. PubMed ID: 16098956
    [Abstract] [Full Text] [Related]

  • 32. Identification of C-β-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies.
    Barr D, Szennyes E, Bokor É, Al-Oanzi ZH, Moffatt C, Kun S, Docsa T, Sipos Á, Davies MP, Mathomes RT, Snape TJ, Agius L, Somsák L, Hayes JM.
    ACS Chem Biol; 2019 Jul 19; 14(7):1460-1470. PubMed ID: 31243960
    [Abstract] [Full Text] [Related]

  • 33. Nanomolar Inhibitors of Glycogen Phosphorylase Based on β-d-Glucosaminyl Heterocycles: A Combined Synthetic, Enzyme Kinetic, and Protein Crystallography Study.
    Bokor É, Kyriakis E, Solovou TGA, Koppány C, Kantsadi AL, Szabó KE, Szakács A, Stravodimos GA, Docsa T, Skamnaki VT, Zographos SE, Gergely P, Leonidas DD, Somsák L.
    J Med Chem; 2017 Nov 22; 60(22):9251-9262. PubMed ID: 28925695
    [Abstract] [Full Text] [Related]

  • 34. van der Waals interactions govern C-β-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
    Kantsadi AL, Stravodimos GA, Kyriakis E, Chatzileontiadou DSM, Solovou TGA, Kun S, Bokor É, Somsák L, Leonidas DD.
    J Struct Biol; 2017 Jul 22; 199(1):57-67. PubMed ID: 28483603
    [Abstract] [Full Text] [Related]

  • 35. Synthesis of alpha- and beta-D-glucopyranosyl triazoles by CuAAC 'click chemistry': reactant tolerance, reaction rate, product structure and glucosidase inhibitory properties.
    Dedola S, Hughes DL, Nepogodiev SA, Rejzek M, Field RA.
    Carbohydr Res; 2010 Jun 16; 345(9):1123-34. PubMed ID: 20427038
    [Abstract] [Full Text] [Related]

  • 36. Dual-Target Compounds against Type 2 Diabetes Mellitus: Proof of Concept for Sodium Dependent Glucose Transporter (SGLT) and Glycogen Phosphorylase (GP) Inhibitors.
    Sipos Á, Szennyes E, Hajnal NÉ, Kun S, Szabó KE, Uray K, Somsák L, Docsa T, Bokor É.
    Pharmaceuticals (Basel); 2021 Apr 15; 14(4):. PubMed ID: 33920838
    [Abstract] [Full Text] [Related]

  • 37. Synthesis of anomeric sulfonamides and their behaviour under radical-mediated bromination conditions.
    Czifrák K, Somsák L.
    Carbohydr Res; 2009 Feb 17; 344(3):269-77. PubMed ID: 19084827
    [Abstract] [Full Text] [Related]

  • 38. Synthesis of oleanolic acid dimers as inhibitors of glycogen phosphorylase.
    Cheng K, Liu J, Sun H, Xie J.
    Chem Biodivers; 2010 Mar 17; 7(3):690-7. PubMed ID: 20232331
    [Abstract] [Full Text] [Related]

  • 39. Novel glucopyranoside C2-derived 1,2,3-triazoles displaying selective inhibition of O-GlcNAcase (OGA).
    Igual MO, Nunes PSG, da Costa RM, Mantoani SP, Tostes RC, Carvalho I.
    Carbohydr Res; 2019 Jan 01; 471():43-55. PubMed ID: 30412832
    [Abstract] [Full Text] [Related]

  • 40. Synthesis of 1,2,3-triazoles from xylosyl and 5-thioxylosyl azides: evaluation of the xylose scaffold for the design of potential glycogen phosphorylase inhibitors.
    Goyard D, Baron M, Skourti PV, Chajistamatiou AS, Docsa T, Gergely P, Chrysina ED, Praly JP, Vidal S.
    Carbohydr Res; 2012 Dec 15; 364():28-40. PubMed ID: 23147043
    [Abstract] [Full Text] [Related]

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