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Journal Abstract Search

3615 related items for PubMed ID: 29547830

  • 1. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
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  • 2. Novel benzotriazole N-acylarylhydrazone hybrids: Design, synthesis, anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis and FAK inhibition.
    Kassab AE, Hassan RA.
    Bioorg Chem; 2018 Oct 25; 80():531-544. PubMed ID: 30014921
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  • 3. Design, synthesis and mechanistic study of N-4-Piperazinyl Butyryl Thiazolidinedione derivatives of ciprofloxacin with Anticancer Activity via Topoisomerase I/II inhibition.
    Aziz HA, El-Saghier AM, Badr M, Elsadek BEM, Abuo-Rahma GEA, Shoman ME.
    Sci Rep; 2024 Oct 15; 14(1):24101. PubMed ID: 39406816
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  • 6. Novel Mannich bases of ciprofloxacin with improved physicochemical properties, antibacterial, anticancer activities and caspase-3 mediated apoptosis.
    Abdel-Rahman IM, Mustafa M, Mohamed SA, Yahia R, Abdel-Aziz M, Abuo-Rahma GEA, Hayallah AM.
    Bioorg Chem; 2021 Feb 15; 107():104629. PubMed ID: 33482607
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  • 7. Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors.
    Eissa IH, Metwaly AM, Belal A, Mehany ABM, Ayyad RR, El-Adl K, Mahdy HA, Taghour MS, El-Gamal KMA, El-Sawah ME, Elmetwally SA, Elhendawy MA, Radwan MM, ElSohly MA.
    Arch Pharm (Weinheim); 2019 Nov 15; 352(11):e1900123. PubMed ID: 31463953
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  • 9. Biological Activity, Apoptotic Induction and Cell Cycle Arrest of New Hydrazonoyl Halides Derivatives.
    Mohamed MF, Hassaneen HM, Elzayat EM, El-Hallouty SM, El-Manawaty M, Saleh FM, Mohamed Y, El-Zohiry D, Fahmy G, Abdelaal N, Hassanin N, Hossam N.
    Anticancer Agents Med Chem; 2019 Nov 15; 19(9):1141-1149. PubMed ID: 30843494
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  • 10. Design, efficient synthesis, docking studies, and anticancer evaluation of new quinoxalines as potential intercalative Topo II inhibitors and apoptosis inducers.
    Abbass EM, Khalil AK, Mohamed MM, Eissa IH, El-Naggar AM.
    Bioorg Chem; 2020 Nov 15; 104():104255. PubMed ID: 32927130
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  • 12. Design, synthesis and biological evaluation of novel α-acyloxy carboxamides via Passerini reaction as caspase 3/7 activators.
    Salah Ayoup M, Wahby Y, Abdel-Hamid H, Ramadan ES, Teleb M, Abu-Serie MM, Noby A.
    Eur J Med Chem; 2019 Apr 15; 168():340-356. PubMed ID: 30826510
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  • 14. New fused pyrimidine derivatives with anticancer activity: Synthesis, topoisomerase II inhibition, apoptotic inducing activity and molecular modeling study.
    Nemr MTM, AboulMagd AM.
    Bioorg Chem; 2020 Oct 15; 103():104134. PubMed ID: 32750610
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  • 15. Novel nalidixic acid derivatives targeting topoisomerase II enzyme; Design, synthesis, anticancer activity and effect on cell cycle profile.
    Khalil OM, Gedawy EM, El-Malah AA, Adly ME.
    Bioorg Chem; 2019 Mar 15; 83():262-276. PubMed ID: 30391699
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  • 16. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG, Bonam SR, Reddy TS, Akunuri R, Naidu VGM, Nayak VL, Bhargava SK, Kumar HMS, Srihari P, Kamal A.
    Eur J Med Chem; 2018 Jan 20; 144():595-611. PubMed ID: 29289884
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  • 17. Novel coumarin-pyrazole carboxamide derivatives as potential topoisomerase II inhibitors: Design, synthesis and antibacterial activity.
    Liu H, Ren ZL, Wang W, Gong JX, Chu MJ, Ma QW, Wang JC, Lv XH.
    Eur J Med Chem; 2018 Sep 05; 157():81-87. PubMed ID: 30075404
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  • 18. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
    Zhao W, Chen L, Li HM, Wang DJ, Li DS, Chen T, Yuan ZP, Tang YJ.
    Bioorg Med Chem; 2014 Jun 01; 22(11):2998-3007. PubMed ID: 24775914
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