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Journal Abstract Search

573 related items for PubMed ID: 29548750

  • 21. Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression.
    Wang D, Yang X, Chen Y, Gong K, Yu M, Gao Y, Wu X, Hu H, Liao C, Han J, Duan Y.
    J Biol Chem; 2020 Nov 20; 295(47):15870-15882. PubMed ID: 32913121
    [Abstract] [Full Text] [Related]

  • 22. Proprotein convertase subtilisin/kexin type 9 expression is transiently up-regulated in the acute period of myocardial infarction in rat.
    Zhang Y, Liu J, Li S, Xu RX, Sun J, Tang Y, Li JJ.
    BMC Cardiovasc Disord; 2014 Dec 17; 14():192. PubMed ID: 25519174
    [Abstract] [Full Text] [Related]

  • 23. Kanglexin, a new anthraquinone compound, attenuates lipid accumulation by activating the AMPK/SREBP-2/PCSK9/LDLR signalling pathway.
    Li X, Hu X, Pan T, Dong L, Ding L, Wang Z, Song R, Wang X, Wang N, Zhang Y, Wang J, Yang B.
    Biomed Pharmacother; 2021 Jan 17; 133():110802. PubMed ID: 33202286
    [Abstract] [Full Text] [Related]

  • 24. Hepatic overexpression of idol increases circulating protein convertase subtilisin/kexin type 9 in mice and hamsters via dual mechanisms: sterol regulatory element-binding protein 2 and low-density lipoprotein receptor-dependent pathways.
    Sasaki M, Terao Y, Ayaori M, Uto-Kondo H, Iizuka M, Yogo M, Hagisawa K, Takiguchi S, Yakushiji E, Nakaya K, Ogura M, Komatsu T, Ikewaki K.
    Arterioscler Thromb Vasc Biol; 2014 Jun 17; 34(6):1171-8. PubMed ID: 24675665
    [Abstract] [Full Text] [Related]

  • 25. Human PCSK9 promotes hepatic lipogenesis and atherosclerosis development via apoE- and LDLR-mediated mechanisms.
    Tavori H, Giunzioni I, Predazzi IM, Plubell D, Shivinsky A, Miles J, Devay RM, Liang H, Rashid S, Linton MF, Fazio S.
    Cardiovasc Res; 2016 May 15; 110(2):268-78. PubMed ID: 26980204
    [Abstract] [Full Text] [Related]

  • 26. Peroxisome Proliferator-activated receptor γ activation by ligands and dephosphorylation induces proprotein convertase subtilisin kexin type 9 and low density lipoprotein receptor expression.
    Duan Y, Chen Y, Hu W, Li X, Yang X, Zhou X, Yin Z, Kong D, Yao Z, Hajjar DP, Liu L, Liu Q, Han J.
    J Biol Chem; 2012 Jul 06; 287(28):23667-77. PubMed ID: 22593575
    [Abstract] [Full Text] [Related]

  • 27. Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine.
    Li H, Dong B, Park SW, Lee HS, Chen W, Liu J.
    J Biol Chem; 2009 Oct 16; 284(42):28885-95. PubMed ID: 19687008
    [Abstract] [Full Text] [Related]

  • 28. Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey.
    Jensen KK, Tadin-Strapps M, Wang SP, Hubert J, Kan Y, Ma Y, McLaren DG, Previs SF, Herath KB, Mahsut A, Liaw A, Wang S, Stout SJ, Keohan C, Forrest G, Coelho D, Yendluri S, Williams S, Koser M, Bartz S, Akinsanya KO, Pinto S.
    J Lipid Res; 2016 Dec 16; 57(12):2150-2162. PubMed ID: 27707816
    [Abstract] [Full Text] [Related]

  • 29. Resveratrol downregulates PCSK9 expression and attenuates steatosis through estrogen receptor α-mediated pathway in L02 cells.
    Jing Y, Hu T, Lin C, Xiong Q, Liu F, Yuan J, Zhao X, Wang R.
    Eur J Pharmacol; 2019 Jul 15; 855():216-226. PubMed ID: 31085239
    [Abstract] [Full Text] [Related]

  • 30. Deferoxamine stimulates LDLR expression and LDL uptake in HepG2 cells.
    Guillemot J, Asselin MC, Susan-Resiga D, Essalmani R, Seidah NG.
    Mol Nutr Food Res; 2016 Mar 15; 60(3):600-8. PubMed ID: 26577249
    [Abstract] [Full Text] [Related]

  • 31. Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism.
    Lebeau P, Al-Hashimi A, Sood S, Lhoták Š, Yu P, Gyulay G, Paré G, Chen SR, Trigatti B, Prat A, Seidah NG, Austin RC.
    J Biol Chem; 2017 Jan 27; 292(4):1510-1523. PubMed ID: 27909053
    [Abstract] [Full Text] [Related]

  • 32. Aloe-emodin exerts cholesterol-lowering effects by inhibiting proprotein convertase subtilisin/kexin type 9 in hyperlipidemic rats.
    Su ZL, Hang PZ, Hu J, Zheng YY, Sun HQ, Guo J, Liu KY, Du ZM.
    Acta Pharmacol Sin; 2020 Aug 27; 41(8):1085-1092. PubMed ID: 32203084
    [Abstract] [Full Text] [Related]

  • 33. Black Raspberry Extract Enhances LDL Uptake in HepG2 Cells by Suppressing PCSK9 Expression to Upregulate LDLR Expression.
    Song KH, Kim YH, Im AR, Kim YH.
    J Med Food; 2018 Jun 27; 21(6):560-567. PubMed ID: 29569973
    [Abstract] [Full Text] [Related]

  • 34. Identification of neolignans with PCSK9 downregulatory and LDLR upregulatory activities from Penthorum chinense and the potential in cholesterol uptake by transcriptional regulation of LDLR via SREBP2.
    Chae HS, Pel P, Cho J, Kim YM, An CY, Huh J, Choi YH, Kim J, Chin YW.
    J Ethnopharmacol; 2021 Oct 05; 278():114265. PubMed ID: 34111537
    [Abstract] [Full Text] [Related]

  • 35. Reduction of circulating PCSK9 and LDL-C levels by liver-specific knockdown of HNF1α in normolipidemic mice.
    Shende VR, Wu M, Singh AB, Dong B, Kan CF, Liu J.
    J Lipid Res; 2015 Apr 05; 56(4):801-9. PubMed ID: 25652089
    [Abstract] [Full Text] [Related]

  • 36. Inflammation Induces Lipid Deposition in Kidneys by Downregulating Renal PCSK9 in Mice with Adriamycin-Induced Nephropathy.
    Zhang G, Li Q.
    Med Sci Monit; 2019 Jul 18; 25():5327-5335. PubMed ID: 31317882
    [Abstract] [Full Text] [Related]

  • 37. Strong induction of PCSK9 gene expression through HNF1alpha and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters.
    Dong B, Wu M, Li H, Kraemer FB, Adeli K, Seidah NG, Park SW, Liu J.
    J Lipid Res; 2010 Jun 18; 51(6):1486-95. PubMed ID: 20048381
    [Abstract] [Full Text] [Related]

  • 38. [Electroacupuncture mitigates hyperlipidemia via improving cholesterol metabolism mediated by SCAP/SREBP-2 signaling in liver tissue in rats].
    Wu H, Zhang ZQ, Chen L, Liao S, Wang XF, Lin W.
    Zhen Ci Yan Jiu; 2023 Apr 25; 48(4):325-30. PubMed ID: 37186195
    [Abstract] [Full Text] [Related]

  • 39.
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  • 40. A small-molecule inhibitor of PCSK9 transcription ameliorates atherosclerosis through the modulation of FoxO1/3 and HNF1α.
    Wang X, Chen X, Zhang X, Su C, Yang M, He W, Du Y, Si S, Wang L, Hong B.
    EBioMedicine; 2020 Feb 25; 52():102650. PubMed ID: 32058941
    [Abstract] [Full Text] [Related]

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