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576 related items for PubMed ID: 29548889

  • 1. Comparison of the hepatic and thyroid gland effects of sodium phenobarbital in wild type and constitutive androstane receptor (CAR) knockout rats and pregnenolone-16α-carbonitrile in wild type and pregnane X receptor (PXR) knockout rats.
    Haines C, Chatham LR, Vardy A, Elcombe CR, Foster JR, Lake BG.
    Toxicology; 2018 May 01; 400-401():20-27. PubMed ID: 29548889
    [Abstract] [Full Text] [Related]

  • 2. Comparison of the hepatic and thyroid gland effects of sodium phenobarbital and pregnenolone-16α-carbonitrile in wild-type and constitutive androstane receptor (CAR)/pregnane X receptor (PXR) knockout rats.
    Haines C, Chatham LR, Vardy A, Elcombe CR, Foster JR, Lake BG.
    Xenobiotica; 2019 Feb 01; 49(2):227-238. PubMed ID: 29424600
    [Abstract] [Full Text] [Related]

  • 3. Comparison of the effects of sodium phenobarbital in wild type and humanized constitutive androstane receptor (CAR)/pregnane X receptor (PXR) mice and in cultured mouse, rat and human hepatocytes.
    Haines C, Elcombe BM, Chatham LR, Vardy A, Higgins LG, Elcombe CR, Lake BG.
    Toxicology; 2018 Mar 01; 396-397():23-32. PubMed ID: 29425889
    [Abstract] [Full Text] [Related]

  • 4. Mode of action analysis for fluxapyroxad-induced rat liver tumour formation: evidence for activation of the constitutive androstane receptor and assessment of human relevance.
    Goettel M, Werner C, Honarvar N, Gröters S, Fegert I, Haines C, Chatham LR, Vardy A, Lake BG.
    Toxicology; 2024 Jun 01; 505():153828. PubMed ID: 38740169
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  • 5. Comparative studies on the effects of sodium phenobarbital and two other constitutive androstane receptor (CAR) activators on induction of cytochrome P450 enzymes and replicative DNA synthesis in cultured hepatocytes from wild type and CAR knockout rats.
    Goettel M, Fegert I, Honarvar N, Vardy A, Haines C, Chatham LR, Lake BG.
    Toxicology; 2020 Mar 30; 433-434():152394. PubMed ID: 32027962
    [Abstract] [Full Text] [Related]

  • 6. Metazachlor: Mode of action analysis for rat liver tumour formation and human relevance.
    Wiemann C, Goettel M, Vardy A, Elcombe BM, Elcombe CR, Chatham LR, Wang H, Li L, Buesen R, Honarvar N, Treumann S, Marxfeld H, Groeters S, Lake BG.
    Toxicology; 2019 Oct 01; 426():152282. PubMed ID: 31465819
    [Abstract] [Full Text] [Related]

  • 7. Piperonyl butoxide: Mode of action analysis for mouse liver tumour formation and human relevance.
    Lake BG, Price RJ, Scott MP, Chatham LR, Vardy A, Osimitz TG.
    Toxicology; 2020 Jun 01; 439():152465. PubMed ID: 32320717
    [Abstract] [Full Text] [Related]

  • 8. Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
    Shizu R, Benoki S, Numakura Y, Kodama S, Miyata M, Yamazoe Y, Yoshinari K.
    PLoS One; 2013 Jun 01; 8(4):e61802. PubMed ID: 23626729
    [Abstract] [Full Text] [Related]

  • 9. The influence of the long-term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice.
    Shizu R, Ishimura M, Nobusawa S, Hosaka T, Sasaki T, Kakizaki S, Yoshinari K.
    Arch Toxicol; 2021 Mar 01; 95(3):1089-1102. PubMed ID: 33398415
    [Abstract] [Full Text] [Related]

  • 10. The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.
    Roques BB, Leghait J, Lacroix MZ, Lasserre F, Pineau T, Viguié C, Martin PG.
    Biochem Pharmacol; 2013 Oct 01; 86(7):997-1039. PubMed ID: 23962444
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  • 14. Studies on the induction of rat hepatic CYP1A, CYP2B, CYP3A and CYP4A subfamily form mRNAs in vivo and in vitro using precision-cut rat liver slices.
    Meredith C, Scott MP, Renwick AB, Price RJ, Lake BG.
    Xenobiotica; 2003 May 01; 33(5):511-27. PubMed ID: 12746107
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  • 16. Constitutive androstane receptor and pregnane X receptor cooperatively ameliorate DSS-induced colitis.
    Uehara D, Tojima H, Kakizaki S, Yamazaki Y, Horiguchi N, Takizawa D, Sato K, Yamada M, Uraoka T.
    Dig Liver Dis; 2019 Feb 01; 51(2):226-235. PubMed ID: 30442521
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  • 18. The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver.
    Konno Y, Kamino H, Moore R, Lih F, Tomer KB, Zeldin DC, Goldstein JA, Negishi M.
    Drug Metab Dispos; 2010 Jul 01; 38(7):1177-82. PubMed ID: 20371638
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  • 19. Use of dominant negative nuclear receptors to study xenobiotic-inducible gene expression in primary cultured hepatocytes.
    Kocarek TA, Shenoy SD, Mercer-Haines NA, Runge-Morris M.
    J Pharmacol Toxicol Methods; 2002 Jul 01; 47(3):177-87. PubMed ID: 12628309
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  • 20. Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
    Luisier R, Lempiäinen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, Müller A, Scheer N, Chibout SD, Hara H, Picard F, Theil D, Couttet P, Vitobello A, Grenet O, Grasl-Kraupp B, Ellinger-Ziegelbauer H, Thomson JP, Meehan RR, Elcombe CR, Henderson CJ, Wolf CR, Schwarz M, Moulin P, Terranova R, Moggs JG.
    Toxicol Sci; 2014 Jun 01; 139(2):501-11. PubMed ID: 24690595
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