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PUBMED FOR HANDHELDS

Journal Abstract Search


674 related items for PubMed ID: 29550533

  • 1. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
    El-Nagar MKS, Abdu-Allah HHM, Salem OIA, Kafafy AN, Farghaly HSM.
    Bioorg Chem; 2018 Aug; 78():80-93. PubMed ID: 29550533
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, anti-inflammatory screening, molecular docking, and COX-1,2/-5-LOX inhibition profile of some novel quinoline derivatives.
    Chaaban I, Rizk OH, Ibrahim TM, Henen SS, El-Khawass EM, Bayad AE, El-Ashmawy IM, Nematalla HA.
    Bioorg Chem; 2018 Aug; 78():220-235. PubMed ID: 29602046
    [Abstract] [Full Text] [Related]

  • 3. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SAM.
    Bioorg Chem; 2017 Jun; 72():102-115. PubMed ID: 28390993
    [Abstract] [Full Text] [Related]

  • 4. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA, Labib MB, Abdel-Latif M.
    Bioorg Chem; 2017 Oct; 74():212-220. PubMed ID: 28865292
    [Abstract] [Full Text] [Related]

  • 5. New benzothiophene derivatives as dual COX-1/2 and 5-LOX inhibitors: synthesis, biological evaluation and docking study.
    El-Miligy MM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SA.
    Future Med Chem; 2017 Apr; 9(5):443-468. PubMed ID: 28362117
    [Abstract] [Full Text] [Related]

  • 6. Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases.
    Rao PN, Chen QH, Knaus EE.
    J Med Chem; 2006 Mar 09; 49(5):1668-83. PubMed ID: 16509583
    [Abstract] [Full Text] [Related]

  • 7. Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.
    Abdu-Allah HHM, Abdelmoez AAB, Tarazi H, El-Shorbagi AA, El-Awady R.
    Bioorg Chem; 2020 Jan 09; 94():103378. PubMed ID: 31677858
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis, analgesic, anti-inflammatory activity of novel pyrazolones possessing aminosulfonyl pharmacophore as inhibitors of COX-2/5-LOX enzymes: Histopathological and docking studies.
    Abdelgawad MA, Labib MB, Ali WAM, Kamel G, Azouz AA, El-Nahass ES.
    Bioorg Chem; 2018 Aug 09; 78():103-114. PubMed ID: 29550530
    [Abstract] [Full Text] [Related]

  • 9. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.
    Maghraby MT, Abou-Ghadir OMF, Abdel-Moty SG, Ali AY, Salem OIA.
    Bioorg Med Chem; 2020 Apr 01; 28(7):115403. PubMed ID: 32127262
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, and biological evaluation of some novel indolizine derivatives as dual cyclooxygenase and lipoxygenase inhibitor for anti-inflammatory activity.
    Shrivastava SK, Srivastava P, Bandresh R, Tripathi PN, Tripathi A.
    Bioorg Med Chem; 2017 Aug 15; 25(16):4424-4432. PubMed ID: 28669741
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis, and biological evaluation of novel 1,2-diaryl-4-substituted-benzylidene-5(4H)-imidazolone derivatives as cytotoxic agents and COX-2/LOX inhibitors.
    Lamie PF, Philoppes JN, Rárová L.
    Arch Pharm (Weinheim); 2018 Apr 15; 351(3-4):e1700311. PubMed ID: 29400411
    [Abstract] [Full Text] [Related]

  • 12. New indomethacin analogs as selective COX-2 inhibitors: Synthesis, COX-1/2 inhibitory activity, anti-inflammatory, ulcerogenicity, histopathological, and docking studies.
    Abdellatif KRA, Abdelall EKA, Elshemy HAH, El-Nahass ES, Abdel-Fattah MM, Abdelgawad YYM.
    Arch Pharm (Weinheim); 2021 Apr 15; 354(4):e2000328. PubMed ID: 33314237
    [Abstract] [Full Text] [Related]

  • 13. Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory activity.
    Abdelrahman MH, Youssif BGM, Abdelgawad MA, Abdelazeem AH, Ibrahim HM, Moustafa AEGA, Treamblu L, Bukhari SNA.
    Eur J Med Chem; 2017 Feb 15; 127():972-985. PubMed ID: 27837994
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, biological evaluation and docking study of novel indole-2-amide as anti-inflammatory agents with dual inhibition of COX and 5-LOX.
    Huang Y, Zhang B, Li J, Liu H, Zhang Y, Yang Z, Liu W.
    Eur J Med Chem; 2019 Oct 15; 180():41-50. PubMed ID: 31299586
    [Abstract] [Full Text] [Related]

  • 15. Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase.
    Shabaan MA, Kamal AM, Faggal SI, Elsahar AE, Mohamed KO.
    Arch Pharm (Weinheim); 2020 Apr 15; 353(4):e1900308. PubMed ID: 32031284
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX.
    Omar YM, Abdu-Allah HHM, Abdel-Moty SG.
    Bioorg Chem; 2018 Oct 15; 80():461-471. PubMed ID: 29986191
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and biological evaluation of novel pyrazole sulfonamide derivatives as dual COX-2/5-LOX inhibitors.
    Gedawy EM, Kassab AE, El Kerdawy AM.
    Eur J Med Chem; 2020 Mar 01; 189():112066. PubMed ID: 31982653
    [Abstract] [Full Text] [Related]

  • 18. Novel click modifiable thioquinazolinones as anti-inflammatory agents: Design, synthesis, biological evaluation and docking study.
    Moussa G, Alaaeddine R, Alaeddine LM, Nassra R, Belal ASF, Ismail A, El-Yazbi AF, Abdel-Ghany YS, Hazzaa A.
    Eur J Med Chem; 2018 Jan 20; 144():635-650. PubMed ID: 29289887
    [Abstract] [Full Text] [Related]

  • 19. Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study.
    Lamie PF, Ali WAM, Bazgier V, Rárová L.
    Eur J Med Chem; 2016 Nov 10; 123():803-813. PubMed ID: 27541263
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors.
    Shaaban MA, Kamal AM, Faggal SI, Farag NA, Aborehab NM, Elsahar AE, Mohamed KO.
    Arch Pharm (Weinheim); 2020 Nov 10; 353(11):e2000027. PubMed ID: 32696514
    [Abstract] [Full Text] [Related]


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