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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

150 related items for PubMed ID: 29602797

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  • 7. Mechanism-based inactivation of CYP2B1 and its F-helix mutant by two tert-butyl acetylenic compounds: covalent modification of prosthetic heme versus apoprotein.
    Lin HL, Zhang H, Noon KR, Hollenberg PF.
    J Pharmacol Exp Ther; 2009 Nov; 331(2):392-403. PubMed ID: 19700628
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  • 8. Identification of 17-alpha-ethynylestradiol-modified active site peptides and glutathione conjugates formed during metabolism and inactivation of P450s 2B1 and 2B6.
    Kent UM, Lin HL, Mills DE, Regal KA, Hollenberg PF.
    Chem Res Toxicol; 2006 Feb; 19(2):279-87. PubMed ID: 16485904
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  • 9. Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).
    He K, Woolf TF, Hollenberg PF.
    J Pharmacol Exp Ther; 1999 Feb; 288(2):791-7. PubMed ID: 9918590
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  • 10. The effect of ritonavir on human CYP2B6 catalytic activity: heme modification contributes to the mechanism-based inactivation of CYP2B6 and CYP3A4 by ritonavir.
    Lin HL, D'Agostino J, Kenaan C, Calinski D, Hollenberg PF.
    Drug Metab Dispos; 2013 Oct; 41(10):1813-24. PubMed ID: 23886699
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  • 15. The functional role of threonine-205 in the mechanism-based inactivation of P450 2B1 by two ethynyl substrates: the importance of the F helix in catalysis.
    Lin HL, Kent UM, Zhang H, Waskell L, Hollenberg PF.
    J Pharmacol Exp Ther; 2004 Dec; 311(3):855-63. PubMed ID: 15302894
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  • 16. Mechanism-based inactivation of cytochrome P450 2B4 by aldehydes: relationship to aldehyde deformylation via a peroxyhemiacetal intermediate.
    Raner GM, Chiang EW, Vaz AD, Coon MJ.
    Biochemistry; 1997 Apr 22; 36(16):4895-902. PubMed ID: 9125510
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  • 17. Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites.
    Kent UM, Mills DE, Rajnarayanan RV, Alworth WL, Hollenberg PF.
    J Pharmacol Exp Ther; 2002 Feb 22; 300(2):549-58. PubMed ID: 11805216
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  • 18. Spectral studies of tert-butyl isothiocyanate-inactivated P450 2E1.
    Kent UM, Roberts-Kirchhoff ES, Moon N, Dunham WR, Hollenberg PF.
    Biochemistry; 2001 Jun 19; 40(24):7253-61. PubMed ID: 11401573
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  • 19. One-electron oxidation of diclofenac by human cytochrome P450s as a potential bioactivation mechanism for formation of 2'-(glutathion-S-yl)-deschloro-diclofenac.
    Boerma JS, Vermeulen NP, Commandeur JN.
    Chem Biol Interact; 2014 Jan 25; 207():32-40. PubMed ID: 24246759
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  • 20. Mechanism-based inactivation of cytochrome P450 2D6 by 1-[(2-ethyl-4-methyl-1H-imidazol-5-yl)methyl]- 4-[4-(trifluoromethyl)-2-pyridinyl]piperazine: kinetic characterization and evidence for apoprotein adduction.
    Hutzler JM, Steenwyk RC, Smith EB, Walker GS, Wienkers LC.
    Chem Res Toxicol; 2004 Feb 25; 17(2):174-84. PubMed ID: 14967005
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