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202 related items for PubMed ID: 29607466

  • 1. Autophagy inhibition improves the chemotherapeutic efficacy of cruciferous vegetable-derived diindolymethane in a murine prostate cancer xenograft model.
    Draz H, Goldberg AA, Tomlinson Guns ES, Fazli L, Safe S, Sanderson JT.
    Invest New Drugs; 2018 Aug; 36(4):718-725. PubMed ID: 29607466
    [Abstract] [Full Text] [Related]

  • 2. Diindolylmethane and its halogenated derivatives induce protective autophagy in human prostate cancer cells via induction of the oncogenic protein AEG-1 and activation of AMP-activated protein kinase (AMPK).
    Draz H, Goldberg AA, Titorenko VI, Tomlinson Guns ES, Safe SH, Sanderson JT.
    Cell Signal; 2017 Dec; 40():172-182. PubMed ID: 28923415
    [Abstract] [Full Text] [Related]

  • 3. Ring-substituted analogs of 3,3'-diindolylmethane (DIM) induce apoptosis and necrosis in androgen-dependent and -independent prostate cancer cells.
    Goldberg AA, Titorenko VI, Beach A, Abdelbaqi K, Safe S, Sanderson JT.
    Invest New Drugs; 2014 Feb; 32(1):25-36. PubMed ID: 23709189
    [Abstract] [Full Text] [Related]

  • 4. Antiandrogenic and growth inhibitory effects of ring-substituted analogs of 3,3'-diindolylmethane (ring-DIMs) in hormone-responsive LNCaP human prostate cancer cells.
    Abdelbaqi K, Lack N, Guns ET, Kotha L, Safe S, Sanderson JT.
    Prostate; 2011 Sep 15; 71(13):1401-12. PubMed ID: 21321979
    [Abstract] [Full Text] [Related]

  • 5. B-DIM impairs radiation-induced survival pathways independently of androgen receptor expression and augments radiation efficacy in prostate cancer.
    Singh-Gupta V, Banerjee S, Yunker CK, Rakowski JT, Joiner MC, Konski AA, Sarkar FH, Hillman GG.
    Cancer Lett; 2012 May 01; 318(1):86-92. PubMed ID: 22155105
    [Abstract] [Full Text] [Related]

  • 6. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induce autophagic cell death in estrogen receptor negative breast cancer.
    Vanderlaag K, Su Y, Frankel AE, Burghardt RC, Barhoumi R, Chadalapaka G, Jutooru I, Safe S.
    BMC Cancer; 2010 Dec 03; 10():669. PubMed ID: 21129193
    [Abstract] [Full Text] [Related]

  • 7. 3,3'-Diindolylmethane induces anti-human gastric cancer cells by the miR-30e-ATG5 modulating autophagy.
    Ye Y, Fang Y, Xu W, Wang Q, Zhou J, Lu R.
    Biochem Pharmacol; 2016 Sep 01; 115():77-84. PubMed ID: 27372603
    [Abstract] [Full Text] [Related]

  • 8. Down-regulation of androgen receptor by 3,3'-diindolylmethane contributes to inhibition of cell proliferation and induction of apoptosis in both hormone-sensitive LNCaP and insensitive C4-2B prostate cancer cells.
    Bhuiyan MM, Li Y, Banerjee S, Ahmed F, Wang Z, Ali S, Sarkar FH.
    Cancer Res; 2006 Oct 15; 66(20):10064-72. PubMed ID: 17047070
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of Autophagy Promotes Hemistepsin A-Induced Apoptosis via Reactive Oxygen Species-Mediated AMPK-Dependent Signaling in Human Prostate Cancer Cells.
    Kim KY, Yun UJ, Yeom SH, Kim SC, Lee HJ, Ahn SC, Park KI, Kim YW.
    Biomolecules; 2021 Dec 01; 11(12):. PubMed ID: 34944451
    [Abstract] [Full Text] [Related]

  • 10. Therapeutic activity of 3,3'-diindolylmethane on prostate cancer in an in vivo model.
    Nachshon-Kedmi M, Fares FA, Yannai S.
    Prostate; 2004 Oct 01; 61(2):153-60. PubMed ID: 15305338
    [Abstract] [Full Text] [Related]

  • 11. Chloroquine enhances the efficacy of cisplatin by suppressing autophagy in human adrenocortical carcinoma treatment.
    Qin L, Xu T, Xia L, Wang X, Zhang X, Zhang X, Zhu Z, Zhong S, Wang C, Shen Z.
    Drug Des Devel Ther; 2016 Oct 01; 10():1035-45. PubMed ID: 27022243
    [Abstract] [Full Text] [Related]

  • 12. Honokiol exhibits enhanced antitumor effects with chloroquine by inducing cell death and inhibiting autophagy in human non-small cell lung cancer cells.
    Lv X, Liu F, Shang Y, Chen SZ.
    Oncol Rep; 2015 Sep 01; 34(3):1289-300. PubMed ID: 26136140
    [Abstract] [Full Text] [Related]

  • 13. 3,3'-Diindolylmethane potentiates paclitaxel-induced antitumor effects on gastric cancer cells through the Akt/FOXM1 signaling cascade.
    Jin H, Park MH, Kim SM.
    Oncol Rep; 2015 Apr 01; 33(4):2031-6. PubMed ID: 25633416
    [Abstract] [Full Text] [Related]

  • 14. Chloroquine enhances temozolomide cytotoxicity in malignant gliomas by blocking autophagy.
    Golden EB, Cho HY, Jahanian A, Hofman FM, Louie SG, Schönthal AH, Chen TC.
    Neurosurg Focus; 2014 Dec 01; 37(6):E12. PubMed ID: 25434381
    [Abstract] [Full Text] [Related]

  • 15. Abrogation of Autophagy by Chloroquine Alone or in Combination with mTOR Inhibitors Induces Apoptosis in Neuroendocrine Tumor Cells.
    Avniel-Polak S, Leibowitz G, Riahi Y, Glaser B, Gross DJ, Grozinsky-Glasberg S.
    Neuroendocrinology; 2016 Dec 01; 103(6):724-37. PubMed ID: 26619207
    [Abstract] [Full Text] [Related]

  • 16. 3,3'-diindolylmethane induction of p75NTR-dependent cell death via the p38 mitogen-activated protein kinase pathway in prostate cancer cells.
    Khwaja FS, Wynne S, Posey I, Djakiew D.
    Cancer Prev Res (Phila); 2009 Jun 01; 2(6):566-71. PubMed ID: 19470787
    [Abstract] [Full Text] [Related]

  • 17. 3,3'-Diindolylmethane enhances taxotere-induced apoptosis in hormone-refractory prostate cancer cells through survivin down-regulation.
    Rahman KM, Banerjee S, Ali S, Ahmad A, Wang Z, Kong D, Sakr WA.
    Cancer Res; 2009 May 15; 69(10):4468-75. PubMed ID: 19435906
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of autophagy by chloroquine induces apoptosis in primary effusion lymphoma in vitro and in vivo through induction of endoplasmic reticulum stress.
    Masud Alam M, Kariya R, Kawaguchi A, Matsuda K, Kudo E, Okada S.
    Apoptosis; 2016 Oct 15; 21(10):1191-201. PubMed ID: 27484211
    [Abstract] [Full Text] [Related]

  • 19. Ubenimex inhibits cell proliferation, migration and invasion by inhibiting the expression of APN and inducing autophagic cell death in prostate cancer cells.
    Wang X, Niu Z, Jia Y, Cui M, Han L, Zhang Y, Liu Z, Bi D, Liu S.
    Oncol Rep; 2016 Apr 15; 35(4):2121-30. PubMed ID: 26846372
    [Abstract] [Full Text] [Related]

  • 20. Activation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivo.
    Chen D, Banerjee S, Cui QC, Kong D, Sarkar FH, Dou QP.
    PLoS One; 2012 Apr 15; 7(10):e47186. PubMed ID: 23056607
    [Abstract] [Full Text] [Related]

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