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472 related items for PubMed ID: 29614261

  • 1. The novel CaMKII inhibitor GS-680 reduces diastolic SR Ca leak and prevents CaMKII-dependent pro-arrhythmic activity.
    Lebek S, Plößl A, Baier M, Mustroph J, Tarnowski D, Lücht CM, Schopka S, Flörchinger B, Schmid C, Zausig Y, Pagratis N, Marchand B, Koltun DO, Hung WK, Ahmadyar S, Belardinelli L, Maier LS, Wagner S.
    J Mol Cell Cardiol; 2018 May; 118():159-168. PubMed ID: 29614261
    [Abstract] [Full Text] [Related]

  • 2. Calcium/calmodulin-dependent protein kinase II contributes to cardiac arrhythmogenesis in heart failure.
    Sag CM, Wadsack DP, Khabbazzadeh S, Abesser M, Grefe C, Neumann K, Opiela MK, Backs J, Olson EN, Brown JH, Neef S, Maier SK, Maier LS.
    Circ Heart Fail; 2009 Nov; 2(6):664-75. PubMed ID: 19919992
    [Abstract] [Full Text] [Related]

  • 3. Reduction of SR Ca2+ leak and arrhythmogenic cellular correlates by SMP-114, a novel CaMKII inhibitor with oral bioavailability.
    Neef S, Mann C, Zwenger A, Dybkova N, Maier LS.
    Basic Res Cardiol; 2017 Jul; 112(4):45. PubMed ID: 28612156
    [Abstract] [Full Text] [Related]

  • 4. Enhanced late INa induces proarrhythmogenic SR Ca leak in a CaMKII-dependent manner.
    Sag CM, Mallwitz A, Wagner S, Hartmann N, Schotola H, Fischer TH, Ungeheuer N, Herting J, Shah AM, Maier LS, Sossalla S, Unsöld B.
    J Mol Cell Cardiol; 2014 Nov; 76():94-105. PubMed ID: 25173923
    [Abstract] [Full Text] [Related]

  • 5. Improvement of cardiomyocyte function by a novel pyrimidine-based CaMKII-inhibitor.
    Neef S, Steffens A, Pellicena P, Mustroph J, Lebek S, Ort KR, Schulman H, Maier LS.
    J Mol Cell Cardiol; 2018 Feb; 115():73-81. PubMed ID: 29294328
    [Abstract] [Full Text] [Related]

  • 6. CaMKII-dependent diastolic SR Ca2+ leak and elevated diastolic Ca2+ levels in right atrial myocardium of patients with atrial fibrillation.
    Neef S, Dybkova N, Sossalla S, Ort KR, Fluschnik N, Neumann K, Seipelt R, Schöndube FA, Hasenfuss G, Maier LS.
    Circ Res; 2010 Apr 02; 106(6):1134-44. PubMed ID: 20056922
    [Abstract] [Full Text] [Related]

  • 7. Calcium-calmodulin kinase II mediates digitalis-induced arrhythmias.
    Gonano LA, Sepúlveda M, Rico Y, Kaetzel M, Valverde CA, Dedman J, Mattiazzi A, Vila Petroff M.
    Circ Arrhythm Electrophysiol; 2011 Dec 02; 4(6):947-57. PubMed ID: 22009705
    [Abstract] [Full Text] [Related]

  • 8. Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase.
    Curran J, Hinton MJ, Ríos E, Bers DM, Shannon TR.
    Circ Res; 2007 Feb 16; 100(3):391-8. PubMed ID: 17234966
    [Abstract] [Full Text] [Related]

  • 9. Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation.
    Voigt N, Li N, Wang Q, Wang W, Trafford AW, Abu-Taha I, Sun Q, Wieland T, Ravens U, Nattel S, Wehrens XH, Dobrev D.
    Circulation; 2012 May 01; 125(17):2059-70. PubMed ID: 22456474
    [Abstract] [Full Text] [Related]

  • 10. Calmodulin kinase II inhibition limits the pro-arrhythmic Ca2+ waves induced by cAMP-phosphodiesterase inhibitors.
    Bobin P, Varin A, Lefebvre F, Fischmeister R, Vandecasteele G, Leroy J.
    Cardiovasc Res; 2016 May 01; 110(1):151-61. PubMed ID: 26851245
    [Abstract] [Full Text] [Related]

  • 11. SR Ca2+-leak and disordered excitation-contraction coupling as the basis for arrhythmogenic and negative inotropic effects of acute ethanol exposure.
    Mustroph J, Wagemann O, Lebek S, Tarnowski D, Ackermann J, Drzymalski M, Pabel S, Schmid C, Wagner S, Sossalla S, Maier LS, Neef S.
    J Mol Cell Cardiol; 2018 Mar 01; 116():81-90. PubMed ID: 29410242
    [Abstract] [Full Text] [Related]

  • 12. Ca(2+) /calmodulin-dependent protein kinase II equally induces sarcoplasmic reticulum Ca(2+) leak in human ischaemic and dilated cardiomyopathy.
    Fischer TH, Eiringhaus J, Dybkova N, Förster A, Herting J, Kleinwächter A, Ljubojevic S, Schmitto JD, Streckfuß-Bömeke K, Renner A, Gummert J, Hasenfuss G, Maier LS, Sossalla S.
    Eur J Heart Fail; 2014 Dec 01; 16(12):1292-300. PubMed ID: 25201344
    [Abstract] [Full Text] [Related]

  • 13. Calcium/calmodulin-dependent kinase II and nitric oxide synthase 1-dependent modulation of ryanodine receptors during β-adrenergic stimulation is restricted to the dyadic cleft.
    Dries E, Santiago DJ, Johnson DM, Gilbert G, Holemans P, Korte SM, Roderick HL, Sipido KR.
    J Physiol; 2016 Oct 15; 594(20):5923-5939. PubMed ID: 27121757
    [Abstract] [Full Text] [Related]

  • 14. CaMKII-dependent SR Ca leak contributes to doxorubicin-induced impaired Ca handling in isolated cardiac myocytes.
    Sag CM, Köhler AC, Anderson ME, Backs J, Maier LS.
    J Mol Cell Cardiol; 2011 Nov 15; 51(5):749-59. PubMed ID: 21819992
    [Abstract] [Full Text] [Related]

  • 15. Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation.
    Curran J, Tang L, Roof SR, Velmurugan S, Millard A, Shonts S, Wang H, Santiago D, Ahmad U, Perryman M, Bers DM, Mohler PJ, Ziolo MT, Shannon TR.
    PLoS One; 2014 Nov 15; 9(2):e87495. PubMed ID: 24498331
    [Abstract] [Full Text] [Related]

  • 16. Late INa increases diastolic SR-Ca2+-leak in atrial myocardium by activating PKA and CaMKII.
    Fischer TH, Herting J, Mason FE, Hartmann N, Watanabe S, Nikolaev VO, Sprenger JU, Fan P, Yao L, Popov AF, Danner BC, Schöndube F, Belardinelli L, Hasenfuss G, Maier LS, Sossalla S.
    Cardiovasc Res; 2015 Jul 01; 107(1):184-96. PubMed ID: 25990311
    [Abstract] [Full Text] [Related]

  • 17. Oxidation- and CaMKII-mediated sarcoplasmic reticulum Ca(2+) leak triggers atrial fibrillation in aging.
    Guo X, Yuan S, Liu Z, Fang Q.
    J Cardiovasc Electrophysiol; 2014 Jun 01; 25(6):645-52. PubMed ID: 24576293
    [Abstract] [Full Text] [Related]

  • 18. Autonomous activation of CaMKII exacerbates diastolic calcium leak during beta-adrenergic stimulation in cardiomyocytes of metabolic syndrome rats.
    Romero-García T, Landa-Galvan HV, Pavón N, Mercado-Morales M, Valdivia HH, Rueda A.
    Cell Calcium; 2020 Nov 01; 91():102267. PubMed ID: 32920522
    [Abstract] [Full Text] [Related]

  • 19. Calcium-calmodulin-dependent protein kinase mediates the intracellular signalling pathways of cardiac apoptosis in mice with impaired glucose tolerance.
    Federico M, Portiansky EL, Sommese L, Alvarado FJ, Blanco PG, Zanuzzi CN, Dedman J, Kaetzel M, Wehrens XHT, Mattiazzi A, Palomeque J.
    J Physiol; 2017 Jun 15; 595(12):4089-4108. PubMed ID: 28105734
    [Abstract] [Full Text] [Related]

  • 20. Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure.
    Ai X, Curran JW, Shannon TR, Bers DM, Pogwizd SM.
    Circ Res; 2005 Dec 09; 97(12):1314-22. PubMed ID: 16269653
    [Abstract] [Full Text] [Related]

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