These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

159 related items for PubMed ID: 29615437

  • 1. Refinement of In Vitro Methods for Identification of Aldehyde Oxidase Substrates Reveals Metabolites of Kinase Inhibitors.
    Dick RA.
    Drug Metab Dispos; 2018 Jun; 46(6):846-859. PubMed ID: 29615437
    [Abstract] [Full Text] [Related]

  • 2. Metabolism of c-Met Kinase Inhibitors Containing Quinoline by Aldehyde Oxidase, Electron Donating, and Steric Hindrance Effect.
    Zhang JW, Xiao W, Gao ZT, Yu ZT, Zhang JYJ.
    Drug Metab Dispos; 2018 Dec; 46(12):1847-1855. PubMed ID: 30209037
    [Abstract] [Full Text] [Related]

  • 3. Hydralazine as a selective probe inactivator of aldehyde oxidase in human hepatocytes: estimation of the contribution of aldehyde oxidase to metabolic clearance.
    Strelevitz TJ, Orozco CC, Obach RS.
    Drug Metab Dispos; 2012 Jul; 40(7):1441-8. PubMed ID: 22522748
    [Abstract] [Full Text] [Related]

  • 4. Cynomolgus monkey as a surrogate for human aldehyde oxidase metabolism of the EGFR inhibitor BIBX1382.
    Hutzler JM, Cerny MA, Yang YS, Asher C, Wong D, Frederick K, Gilpin K.
    Drug Metab Dispos; 2014 Oct; 42(10):1751-60. PubMed ID: 25035284
    [Abstract] [Full Text] [Related]

  • 5. Characterization of aldehyde oxidase enzyme activity in cryopreserved human hepatocytes.
    Hutzler JM, Yang YS, Albaugh D, Fullenwider CL, Schmenk J, Fisher MB.
    Drug Metab Dispos; 2012 Feb; 40(2):267-75. PubMed ID: 22031625
    [Abstract] [Full Text] [Related]

  • 6. In Vitro Metabolism by Aldehyde Oxidase Leads to Poor Pharmacokinetic Profile in Rats for c-Met Inhibitor MET401.
    Zhang JW, Deng HB, Zhang CY, Dai JQ, Li Q, Zheng QG, Wan HX, Yu HP, He F, Xu YC, Zhao S, Zhang JYJ.
    Eur J Drug Metab Pharmacokinet; 2019 Oct; 44(5):669-680. PubMed ID: 31030415
    [Abstract] [Full Text] [Related]

  • 7. Species-Specific Involvement of Aldehyde Oxidase and Xanthine Oxidase in the Metabolism of the Pyrimidine-Containing mGlu5-Negative Allosteric Modulator VU0424238 (Auglurant).
    Crouch RD, Blobaum AL, Felts AS, Conn PJ, Lindsley CW.
    Drug Metab Dispos; 2017 Dec; 45(12):1245-1259. PubMed ID: 28939686
    [Abstract] [Full Text] [Related]

  • 8. Aldehyde oxidase activity and inhibition in hepatocytes and cytosolic fractions from mouse, rat, monkey and human.
    Sahi J, Khan KK, Black CB.
    Drug Metab Lett; 2008 Aug; 2(3):176-83. PubMed ID: 19356090
    [Abstract] [Full Text] [Related]

  • 9. A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834.
    Sodhi JK, Wong S, Kirkpatrick DS, Liu L, Khojasteh SC, Hop CE, Barr JT, Jones JP, Halladay JS.
    Drug Metab Dispos; 2015 Jun; 43(6):908-15. PubMed ID: 25845827
    [Abstract] [Full Text] [Related]

  • 10. Evaluation of Cytochrome P450 Selectivity for Hydralazine as an Aldehyde Oxidase Inhibitor for Reaction Phenotyping.
    Yang X, Johnson N, Di L.
    J Pharm Sci; 2019 Apr; 108(4):1627-1630. PubMed ID: 30448524
    [Abstract] [Full Text] [Related]

  • 11. Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach.
    Adusumalli S, Jamwal R, Obach RS, Ryder TF, Leggio L, Akhlaghi F.
    Drug Metab Dispos; 2019 Aug; 47(8):874-882. PubMed ID: 31182423
    [Abstract] [Full Text] [Related]

  • 12. Oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase.
    Inoue K, Mizuo H, Kawaguchi S, Fukuda K, Kusano K, Yoshimura T.
    Drug Metab Dispos; 2014 Aug; 42(8):1326-33. PubMed ID: 24914245
    [Abstract] [Full Text] [Related]

  • 13. Metabolism of xenobiotics by aldehyde oxidase.
    Dalvie D, Zientek M.
    Curr Protoc Toxicol; 2015 Feb 02; 63():4.41.1-4.41.13. PubMed ID: 25645247
    [Abstract] [Full Text] [Related]

  • 14. Monoamine oxidase B oxidizes a novel multikinase inhibitor KW-2449 to its iminium ion and aldehyde oxidase further converts it to the oxo-piperazine form in human.
    Hosogi J, Ohashi R, Maeda H, Tashiro S, Fuse E, Yamamoto Y, Kuwabara T.
    Drug Metab Pharmacokinet; 2017 Oct 02; 32(5):255-264. PubMed ID: 28751116
    [Abstract] [Full Text] [Related]

  • 15. Species-specific metabolism of SGX523 by aldehyde oxidase and the toxicological implications.
    Diamond S, Boer J, Maduskuie TP, Falahatpisheh N, Li Y, Yeleswaram S.
    Drug Metab Dispos; 2010 Aug 02; 38(8):1277-85. PubMed ID: 20421447
    [Abstract] [Full Text] [Related]

  • 16. Aldehyde oxidase-dependent species difference in hepatic metabolism of fasudil to hydroxyfasudil.
    Mao Z, Wu Y, Li Q, Wang X, Liu Y, Di X.
    Xenobiotica; 2018 Feb 02; 48(2):170-177. PubMed ID: 28166443
    [Abstract] [Full Text] [Related]

  • 17. Lack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro Methods.
    Jensen KG, Jacobsen AM, Bundgaard C, Nilausen DØ, Thale Z, Chandrasena G, Jørgensen M.
    Drug Metab Dispos; 2017 Jan 02; 45(1):68-75. PubMed ID: 27737930
    [Abstract] [Full Text] [Related]

  • 18. The Drug-Drug Interaction between Erlotinib and OSI-930 Is Mediated through Aldehyde Oxidase Inhibition.
    Tang LWT, Shi Y, Sharma R, Obach RS.
    Drug Metab Dispos; 2024 Aug 14; 52(9):1020-1028. PubMed ID: 38889967
    [Abstract] [Full Text] [Related]

  • 19. A novel in vitro allometric scaling methodology for aldehyde oxidase substrates to enable selection of appropriate species for traditional allometry.
    Crouch RD, Hutzler JM, Daniels JS.
    Xenobiotica; 2018 Mar 14; 48(3):219-231. PubMed ID: 28281401
    [Abstract] [Full Text] [Related]

  • 20. Zebularine metabolism by aldehyde oxidase in hepatic cytosol from humans, monkeys, dogs, rats, and mice: influence of sex and inhibitors.
    Klecker RW, Cysyk RL, Collins JM.
    Bioorg Med Chem; 2006 Jan 01; 14(1):62-6. PubMed ID: 16143537
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 8.