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375 related items for PubMed ID: 29626488

  • 1. Berberine induced modulation of PHLPP2-Akt-MST1 kinase signaling is coupled with mitochondrial impairment and hepatoma cell death.
    Saxena S, Shukla S, Kakkar P.
    Toxicol Appl Pharmacol; 2018 May 15; 347():92-103. PubMed ID: 29626488
    [Abstract] [Full Text] [Related]

  • 2. FoxO proteins' nuclear retention and BH3-only protein Bim induction evoke mitochondrial dysfunction-mediated apoptosis in berberine-treated HepG2 cells.
    Shukla S, Rizvi F, Raisuddin S, Kakkar P.
    Free Radic Biol Med; 2014 Nov 15; 76():185-99. PubMed ID: 25128467
    [Abstract] [Full Text] [Related]

  • 3. Gambogenic acid induced mitochondrial-dependent apoptosis and referred to phospho-Erk1/2 and phospho-p38 MAPK in human hepatoma HepG2 cells.
    Yan F, Wang M, Li J, Cheng H, Su J, Wang X, Wu H, Xia L, Li X, Chang HC, Li Q.
    Environ Toxicol Pharmacol; 2012 Mar 15; 33(2):181-90. PubMed ID: 22222560
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  • 4. BBR induces apoptosis in HepG2 cell through an Akt-ASK1-ROS-p38MAPKs-linked cascade.
    Hyun MS, Hur JM, Mun YJ, Kim D, Woo WH.
    J Cell Biochem; 2010 Feb 01; 109(2):329-38. PubMed ID: 19950206
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  • 5. Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells.
    Liao YJ, Bai HY, Li ZH, Zou J, Chen JW, Zheng F, Zhang JX, Mai SJ, Zeng MS, Sun HD, Pu JX, Xie D.
    Cell Death Dis; 2014 Mar 20; 5(3):e1137. PubMed ID: 24651440
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  • 6. Ergosterol peroxide activates Foxo3-mediated cell death signaling by inhibiting AKT and c-Myc in human hepatocellular carcinoma cells.
    Li X, Wu Q, Bu M, Hu L, Du WW, Jiao C, Pan H, Sdiri M, Wu N, Xie Y, Yang BB.
    Oncotarget; 2016 Jun 07; 7(23):33948-59. PubMed ID: 27058618
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  • 7. Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis.
    Kim K, Ryu D, Dongiovanni P, Ozcan L, Nayak S, Ueberheide B, Valenti L, Auwerx J, Pajvani UB.
    Gastroenterology; 2017 Dec 07; 153(6):1568-1580.e10. PubMed ID: 28859855
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  • 8. Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis.
    Qiao M, Wang Y, Xu X, Lu J, Dong Y, Tao W, Stein J, Stein GS, Iglehart JD, Shi Q, Pardee AB.
    Mol Cell; 2010 May 28; 38(4):512-23. PubMed ID: 20513427
    [Abstract] [Full Text] [Related]

  • 9. Supercritical carbon dioxide extraction of aromatic turmerone from Curcuma longa Linn. induces apoptosis through reactive oxygen species-triggered intrinsic and extrinsic pathways in human hepatocellular carcinoma HepG2 cells.
    Cheng SB, Wu LC, Hsieh YC, Wu CH, Chan YJ, Chang LH, Chang CM, Hsu SL, Teng CL, Wu CC.
    J Agric Food Chem; 2012 Sep 26; 60(38):9620-30. PubMed ID: 22946656
    [Abstract] [Full Text] [Related]

  • 10. Concurrent acetylation of FoxO1/3a and p53 due to sirtuins inhibition elicit Bim/PUMA mediated mitochondrial dysfunction and apoptosis in berberine-treated HepG2 cells.
    Shukla S, Sharma A, Pandey VK, Raisuddin S, Kakkar P.
    Toxicol Appl Pharmacol; 2016 Jan 15; 291():70-83. PubMed ID: 26712469
    [Abstract] [Full Text] [Related]

  • 11. Inhibitory effects of interferon-β on hepatocellular carcinoma HepG2 via Akt/STAT phosphorylation.
    Ethiraj P, Veerappan K, Samuel S, Sivapatham S.
    Fundam Clin Pharmacol; 2015 Jun 15; 29(3):278-85. PubMed ID: 25773664
    [Abstract] [Full Text] [Related]

  • 12. Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells.
    Burgeiro A, Gajate C, Dakir el H, Villa-Pulgarín JA, Oliveira PJ, Mollinedo F.
    Anticancer Drugs; 2011 Jul 15; 22(6):507-18. PubMed ID: 21527846
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  • 13. Coumestrol induces mitochondrial dysfunction by stimulating ROS production and calcium ion influx into mitochondria in human placental choriocarcinoma cells.
    Lim W, Yang C, Jeong M, Bazer FW, Song G.
    Mol Hum Reprod; 2017 Nov 01; 23(11):786-802. PubMed ID: 29040664
    [Abstract] [Full Text] [Related]

  • 14. Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.
    Hsu WH, Hsieh YS, Kuo HC, Teng CY, Huang HI, Wang CJ, Yang SF, Liou YS, Kuo WH.
    Arch Toxicol; 2007 Oct 01; 81(10):719-28. PubMed ID: 17673978
    [Abstract] [Full Text] [Related]

  • 15. Liquiritin inhibits proliferation and induces apoptosis in HepG2 hepatocellular carcinoma cells via the ROS-mediated MAPK/AKT/NF-κB signaling pathway.
    Wang JR, Li TZ, Wang C, Li SM, Luo YH, Piao XJ, Feng YC, Zhang Y, Xu WT, Zhang Y, Zhang T, Wang SN, Xue H, Wang HX, Cao LK, Jin CH.
    Naunyn Schmiedebergs Arch Pharmacol; 2020 Oct 01; 393(10):1987-1999. PubMed ID: 31956937
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  • 16. Berberine induces selective apoptosis through the AMPK‑mediated mitochondrial/caspase pathway in hepatocellular carcinoma.
    Yang X, Huang N.
    Mol Med Rep; 2013 Aug 01; 8(2):505-10. PubMed ID: 23732865
    [Abstract] [Full Text] [Related]

  • 17. Induction of Apoptosis by Coptisine in Hep3B Hepatocellular Carcinoma Cells through Activation of the ROS-Mediated JNK Signaling Pathway.
    Kim SY, Hwangbo H, Lee H, Park C, Kim GY, Moon SK, Yun SJ, Kim WJ, Cheong J, Choi YH.
    Int J Mol Sci; 2020 Jul 31; 21(15):. PubMed ID: 32752099
    [Abstract] [Full Text] [Related]

  • 18. Reactive oxygen species-mitochondria pathway involved in FV-429-induced apoptosis in human hepatocellular carcinoma HepG2 cells.
    Yang Z, Qiang L, Wu T, Chen FH, Yang HY, Zhao Q, Zou MJ, Sun YJ, Li ZY, Guo QL.
    Anticancer Drugs; 2011 Oct 31; 22(9):886-95. PubMed ID: 21730822
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  • 19. DMFC (3,5-dimethyl-7H-furo[3,2-g]chromen-7-one) regulates Bim to trigger Bax and Bak activation to suppress drug-resistant human hepatoma.
    Xiang J, Wang Z, Liu Q, Li X, Sun J, Fung KP, Liu F.
    Apoptosis; 2017 Mar 31; 22(3):381-392. PubMed ID: 27873035
    [Abstract] [Full Text] [Related]

  • 20. β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular carcinoma.
    Zhang G, He J, Ye X, Zhu J, Hu X, Shen M, Ma Y, Mao Z, Song H, Chen F.
    Cell Death Dis; 2019 Mar 15; 10(4):255. PubMed ID: 30874538
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