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232 related items for PubMed ID: 29637772

  • 1. The Gelsolin Pathogenic D187N Mutant Exhibits Altered Conformational Stability and Forms Amyloidogenic Oligomers.
    Srivastava A, Singh J, Singh Yadav SP, Arya P, Kalim F, Rose P, Ashish, Kundu B.
    Biochemistry; 2018 Apr 24; 57(16):2359-2372. PubMed ID: 29637772
    [Abstract] [Full Text] [Related]

  • 2. Nanobody interaction unveils structure, dynamics and proteotoxicity of the Finnish-type amyloidogenic gelsolin variant.
    Giorgino T, Mattioni D, Hassan A, Milani M, Mastrangelo E, Barbiroli A, Verhelle A, Gettemans J, Barzago MM, Diomede L, de Rosa M.
    Biochim Biophys Acta Mol Basis Dis; 2019 Mar 01; 1865(3):648-660. PubMed ID: 30625383
    [Abstract] [Full Text] [Related]

  • 3. Effect of position-specific single-point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophy patients.
    Anandalakshmi V, Murugan E, Leng EGT, Ting LW, Chaurasia SS, Yamazaki T, Nagashima T, George BL, Peh GSL, Pervushin K, Lakshminarayanan R, Mehta JS.
    Biochem J; 2017 May 09; 474(10):1705-1725. PubMed ID: 28381645
    [Abstract] [Full Text] [Related]

  • 4. Amyloid fibril formation in gelsolin-derived amyloidosis. Definition of the amyloidogenic region and evidence of accelerated amyloid formation of mutant Asn-187 and Tyr-187 gelsolin peptides.
    Maury CP, Nurmiaho-Lassila EL, Rossi H.
    Lab Invest; 1994 Apr 09; 70(4):558-64. PubMed ID: 8176895
    [Abstract] [Full Text] [Related]

  • 5. The amyloidogenicity of gelsolin is controlled by proteolysis and pH.
    Ratnaswamy G, Koepf E, Bekele H, Yin H, Kelly JW.
    Chem Biol; 1999 May 09; 6(5):293-304. PubMed ID: 10322122
    [Abstract] [Full Text] [Related]

  • 6. Gelsolin amyloidosis: genetics, biochemistry, pathology and possible strategies for therapeutic intervention.
    Solomon JP, Page LJ, Balch WE, Kelly JW.
    Crit Rev Biochem Mol Biol; 2012 May 09; 47(3):282-96. PubMed ID: 22360545
    [Abstract] [Full Text] [Related]

  • 7. The structure of N184K amyloidogenic variant of gelsolin highlights the role of the H-bond network for protein stability and aggregation properties.
    de Rosa M, Barbiroli A, Bonì F, Scalone E, Mattioni D, Vanoni MA, Patrone M, Bollati M, Mastrangelo E, Giorgino T, Milani M.
    Eur Biophys J; 2020 Jan 09; 49(1):11-19. PubMed ID: 31724080
    [Abstract] [Full Text] [Related]

  • 8. Gelsolin pathogenic Gly167Arg mutation promotes domain-swap dimerization of the protein.
    Bonì F, Milani M, Barbiroli A, Diomede L, Mastrangelo E, de Rosa M.
    Hum Mol Genet; 2018 Jan 01; 27(1):53-65. PubMed ID: 29069428
    [Abstract] [Full Text] [Related]

  • 9. The 8 and 5 kDa fragments of plasma gelsolin form amyloid fibrils by a nucleated polymerization mechanism, while the 68 kDa fragment is not amyloidogenic.
    Solomon JP, Yonemoto IT, Murray AN, Price JL, Powers ET, Balch WE, Kelly JW.
    Biochemistry; 2009 Dec 08; 48(48):11370-80. PubMed ID: 19904968
    [Abstract] [Full Text] [Related]

  • 10. Selective interception of gelsolin amyloidogenic stretch results in conformationally distinct aggregates with reduced toxicity.
    Arya P, Srivastava A, Vasaikar SV, Mukherjee G, Mishra P, Kundu B.
    ACS Chem Neurosci; 2014 Oct 15; 5(10):982-92. PubMed ID: 25118567
    [Abstract] [Full Text] [Related]

  • 11. Heparin binds 8 kDa gelsolin cross-β-sheet oligomers and accelerates amyloidogenesis by hastening fibril extension.
    Solomon JP, Bourgault S, Powers ET, Kelly JW.
    Biochemistry; 2011 Apr 05; 50(13):2486-98. PubMed ID: 21348501
    [Abstract] [Full Text] [Related]

  • 12. Aggregation of gelsolin wild-type and G167K/R, N184K, and D187N/Y mutant peptides and inhibition.
    Ahmad M, Esposto J, Golec C, Wu C, Martic-Milne S.
    Mol Cell Biochem; 2021 Jun 05; 476(6):2393-2408. PubMed ID: 33598831
    [Abstract] [Full Text] [Related]

  • 13. Gelsolin domain 2 Ca2+ affinity determines susceptibility to furin proteolysis and familial amyloidosis of finnish type.
    Huff ME, Page LJ, Balch WE, Kelly JW.
    J Mol Biol; 2003 Nov 14; 334(1):119-27. PubMed ID: 14596804
    [Abstract] [Full Text] [Related]

  • 14. Fibrillogenesis in gelsolin-related familial amyloidosis.
    Maury CP, Nurmiaho-Lassila EL, Boysen G, Liljeström M.
    Amyloid; 2003 Aug 14; 10 Suppl 1():21-5. PubMed ID: 14640038
    [Abstract] [Full Text] [Related]

  • 15. Elucidating the mechanism of familial amyloidosis- Finnish type: NMR studies of human gelsolin domain 2.
    Kazmirski SL, Howard MJ, Isaacson RL, Fersht AR.
    Proc Natl Acad Sci U S A; 2000 Sep 26; 97(20):10706-11. PubMed ID: 10995458
    [Abstract] [Full Text] [Related]

  • 16. 1-Palmitoyl-2-(9'-oxononanoyl)-sn-glycero-3-phosphocholine, an oxidized phospholipid, accelerates Finnish type familial gelsolin amyloidosis in vitro.
    Mahalka AK, Maury CP, Kinnunen PK.
    Biochemistry; 2011 Jun 07; 50(22):4877-89. PubMed ID: 21545139
    [Abstract] [Full Text] [Related]

  • 17. pH Induced Conformational Transitions in the Transforming Growth Factor β-Induced Protein (TGFβIp) Associated Corneal Dystrophy Mutants.
    Murugan E, Venkatraman A, Lei Z, Mouvet V, Rui Yi Lim R, Muruganantham N, Goh E, Swee Lim Peh G, Beuerman RW, Chaurasia SS, Rajamani L, Mehta JS.
    Sci Rep; 2016 Mar 31; 6():23836. PubMed ID: 27030015
    [Abstract] [Full Text] [Related]

  • 18. Destabilization of Ca2+-free gelsolin may not be responsible for proteolysis in Familial Amyloidosis of Finnish Type.
    Ratnaswamy G, Huff ME, Su AI, Rion S, Kelly JW.
    Proc Natl Acad Sci U S A; 2001 Feb 27; 98(5):2334-9. PubMed ID: 11226240
    [Abstract] [Full Text] [Related]

  • 19. Preparation of Crystalline Samples of Amyloid Fibrils and Oligomers.
    Moshe A, Landau M, Eisenberg D.
    Methods Mol Biol; 2016 Feb 27; 1345():201-10. PubMed ID: 26453214
    [Abstract] [Full Text] [Related]

  • 20. Identification of a novel human islet amyloid polypeptide beta-sheet domain and factors influencing fibrillogenesis.
    Jaikaran ET, Higham CE, Serpell LC, Zurdo J, Gross M, Clark A, Fraser PE.
    J Mol Biol; 2001 May 04; 308(3):515-25. PubMed ID: 11327784
    [Abstract] [Full Text] [Related]

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