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194 related items for PubMed ID: 29649119

  • 1. Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding.
    Gustafsson R, Zhang S, Masuyer G, Dong M, Stenmark P.
    Toxins (Basel); 2018 Apr 12; 10(4):. PubMed ID: 29649119
    [Abstract] [Full Text] [Related]

  • 2. Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C.
    Benoit RM, Schärer MA, Wieser MM, Li X, Frey D, Kammerer RA.
    Sci Rep; 2017 Mar 02; 7():43588. PubMed ID: 28252640
    [Abstract] [Full Text] [Related]

  • 3. Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A.
    Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, McMillan D, Ceska T, Lebon F, Jaussi R, Steinmetz MO, Schertler GF, Hoogenraad CC, Capitani G, Kammerer RA.
    Nature; 2014 Jan 02; 505(7481):108-11. PubMed ID: 24240280
    [Abstract] [Full Text] [Related]

  • 4. Botulinum Neurotoxin Serotype A Recognizes Its Protein Receptor SV2 by a Different Mechanism than Botulinum Neurotoxin B Synaptotagmin.
    Weisemann J, Stern D, Mahrhold S, Dorner BG, Rummel A.
    Toxins (Basel); 2016 May 17; 8(5):. PubMed ID: 27196927
    [Abstract] [Full Text] [Related]

  • 5. Understanding peptide competitive inhibition of botulinum neurotoxin A binding to SV2 protein via molecular dynamics simulations.
    Chang S, He HQ, Shen L, Wan H.
    Biopolymers; 2015 Oct 17; 103(10):597-608. PubMed ID: 26178648
    [Abstract] [Full Text] [Related]

  • 6. Structural insights into the interaction of botulinum neurotoxin a with its neuronal receptor SV2C.
    Li X, Brunner C, Wu Y, Leka O, Schneider G, Kammerer RA.
    Toxicon; 2020 Feb 17; 175():36-43. PubMed ID: 31783045
    [Abstract] [Full Text] [Related]

  • 7. Structural basis of botulinum neurotoxin serotype A1 binding to human SV2A or SV2C receptors.
    Azzaz F, Hilaire D, Fantini J.
    Chem Biol Interact; 2023 Mar 01; 373():110384. PubMed ID: 36754227
    [Abstract] [Full Text] [Related]

  • 8. N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A.
    Yao G, Zhang S, Mahrhold S, Lam KH, Stern D, Bagramyan K, Perry K, Kalkum M, Rummel A, Dong M, Jin R.
    Nat Struct Mol Biol; 2016 Jul 01; 23(7):656-62. PubMed ID: 27294781
    [Abstract] [Full Text] [Related]

  • 9. Only the complex N559-glycan in the synaptic vesicle glycoprotein 2C mediates high affinity binding to botulinum neurotoxin serotype A1.
    Mahrhold S, Bergström T, Stern D, Dorner BG, Åstot C, Rummel A.
    Biochem J; 2016 Sep 01; 473(17):2645-54. PubMed ID: 27313224
    [Abstract] [Full Text] [Related]

  • 10. Molecular dynamics simulations of wild type and mutants of botulinum neurotoxin A complexed with synaptic vesicle protein 2C.
    Wang F, Wan H, Hu JP, Chang S.
    Mol Biosyst; 2015 Jan 01; 11(1):223-31. PubMed ID: 25358067
    [Abstract] [Full Text] [Related]

  • 11. SV2 is the protein receptor for botulinum neurotoxin A.
    Dong M, Yeh F, Tepp WH, Dean C, Johnson EA, Janz R, Chapman ER.
    Science; 2006 Apr 28; 312(5773):592-6. PubMed ID: 16543415
    [Abstract] [Full Text] [Related]

  • 12. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F.
    Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR.
    Biochemistry; 2009 Jun 23; 48(24):5631-41. PubMed ID: 19476346
    [Abstract] [Full Text] [Related]

  • 13. Botulinum neurotoxins: new questions arising from structural biology.
    Kammerer RA, Benoit RM.
    Trends Biochem Sci; 2014 Nov 23; 39(11):517-26. PubMed ID: 25282537
    [Abstract] [Full Text] [Related]

  • 14. Structure of the BoNT/A1--receptor complex.
    Benoit RM, Frey D, Wieser MM, Thieltges KM, Jaussi R, Capitani G, Kammerer RA.
    Toxicon; 2015 Dec 01; 107(Pt A):25-31. PubMed ID: 26260692
    [Abstract] [Full Text] [Related]

  • 15. A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding.
    Yao G, Lam KH, Weisemann J, Peng L, Krez N, Perry K, Shoemaker CB, Dong M, Rummel A, Jin R.
    Sci Rep; 2017 Aug 07; 7(1):7438. PubMed ID: 28785006
    [Abstract] [Full Text] [Related]

  • 16. Botulinum neurotoxin D uses synaptic vesicle protein SV2 and gangliosides as receptors.
    Peng L, Tepp WH, Johnson EA, Dong M.
    PLoS Pathog; 2011 Mar 07; 7(3):e1002008. PubMed ID: 21483489
    [Abstract] [Full Text] [Related]

  • 17. The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves.
    Mahrhold S, Rummel A, Bigalke H, Davletov B, Binz T.
    FEBS Lett; 2006 Apr 03; 580(8):2011-4. PubMed ID: 16545378
    [Abstract] [Full Text] [Related]

  • 18. Structural basis for botulinum neurotoxin E recognition of synaptic vesicle protein 2.
    Liu Z, Lee PG, Krez N, Lam KH, Liu H, Przykopanski A, Chen P, Yao G, Zhang S, Tremblay JM, Perry K, Shoemaker CB, Rummel A, Dong M, Jin R.
    Nat Commun; 2023 Apr 24; 14(1):2338. PubMed ID: 37095076
    [Abstract] [Full Text] [Related]

  • 19. Association of botulinum neurotoxin serotypes a and B with synaptic vesicle protein complexes.
    Baldwin MR, Barbieri JT.
    Biochemistry; 2007 Mar 20; 46(11):3200-10. PubMed ID: 17311420
    [Abstract] [Full Text] [Related]

  • 20. A Comprehensive Structural Analysis of Clostridium botulinum Neurotoxin A Cell-Binding Domain from Different Subtypes.
    Gregory KS, Acharya KR.
    Toxins (Basel); 2023 Jan 18; 15(2):. PubMed ID: 36828407
    [Abstract] [Full Text] [Related]


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