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Journal Abstract Search


480 related items for PubMed ID: 29649743

  • 1. Recent advances in trimethoxyphenyl (TMP) based tubulin inhibitors targeting the colchicine binding site.
    Li L, Jiang S, Li X, Liu Y, Su J, Chen J.
    Eur J Med Chem; 2018 May 10; 151():482-494. PubMed ID: 29649743
    [Abstract] [Full Text] [Related]

  • 2. Recent Advances in Heterocyclic Tubulin Inhibitors Targeting the Colchicine Binding Site.
    Wu X, Wang Q, Li W.
    Anticancer Agents Med Chem; 2016 May 10; 16(10):1325-38. PubMed ID: 26899186
    [Abstract] [Full Text] [Related]

  • 3. Structural insights into the design of indole derivatives as tubulin polymerization inhibitors.
    Li Y, Yang J, Niu L, Hu D, Li H, Chen L, Yu Y, Chen Q.
    FEBS Lett; 2020 Jan 10; 594(1):199-204. PubMed ID: 31369682
    [Abstract] [Full Text] [Related]

  • 4. Discovery of small molecule inhibitors that interact with γ-tubulin.
    Friesen DE, Barakat KH, Semenchenko V, Perez-Pineiro R, Fenske BW, Mane J, Wishart DS, Tuszynski JA.
    Chem Biol Drug Des; 2012 May 10; 79(5):639-52. PubMed ID: 22268380
    [Abstract] [Full Text] [Related]

  • 5. Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the Colchicine Binding Site in Tubulin.
    Wang Q, Arnst KE, Wang Y, Kumar G, Ma D, White SW, Miller DD, Li W, Li W.
    J Med Chem; 2019 Jul 25; 62(14):6734-6750. PubMed ID: 31251599
    [Abstract] [Full Text] [Related]

  • 6. The compound millepachine and its derivatives inhibit tubulin polymerization by irreversibly binding to the colchicine-binding site in β-tubulin.
    Yang J, Yan W, Yu Y, Wang Y, Yang T, Xue L, Yuan X, Long C, Liu Z, Chen X, Hu M, Zheng L, Qiu Q, Pei H, Li D, Wang F, Bai P, Wen J, Ye H, Chen L.
    J Biol Chem; 2018 Jun 15; 293(24):9461-9472. PubMed ID: 29691282
    [Abstract] [Full Text] [Related]

  • 7. Butterfly Structure: A Privileged Scaffold Targeting Tubulin-Colchicine Binding Site.
    Wang Y, Yao Y, Zhu HL, Duan Y.
    Curr Top Med Chem; 2020 Jun 15; 20(17):1505-1508. PubMed ID: 32543362
    [Abstract] [Full Text] [Related]

  • 8. Targeting Tubulin-colchicine Site for Cancer Therapy: Inhibitors, Antibody- Drug Conjugates and Degradation Agents.
    Duan Y, Liu W, Tian L, Mao Y, Song C.
    Curr Top Med Chem; 2019 Jun 15; 19(15):1289-1304. PubMed ID: 31210108
    [Abstract] [Full Text] [Related]

  • 9. Novel Natural Product- and Privileged Scaffold-Based Tubulin Inhibitors Targeting the Colchicine Binding Site.
    Dong M, Liu F, Zhou H, Zhai S, Yan B.
    Molecules; 2016 Oct 15; 21(10):. PubMed ID: 27754459
    [Abstract] [Full Text] [Related]

  • 10. New ligands of the tubulin colchicine site based on X-ray structures.
    Álvarez R, Medarde M, Peláez R.
    Curr Top Med Chem; 2014 Oct 15; 14(20):2231-52. PubMed ID: 25434358
    [Abstract] [Full Text] [Related]

  • 11. Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
    Wang Y, Zhang H, Gigant B, Yu Y, Wu Y, Chen X, Lai Q, Yang Z, Chen Q, Yang J.
    FEBS J; 2016 Jan 15; 283(1):102-11. PubMed ID: 26462166
    [Abstract] [Full Text] [Related]

  • 12. Tubulin inhibitors targeting the colchicine binding site: a perspective of privileged structures.
    Li W, Sun H, Xu S, Zhu Z, Xu J.
    Future Med Chem; 2017 Oct 15; 9(15):1765-1794. PubMed ID: 28929799
    [Abstract] [Full Text] [Related]

  • 13. New indole-based chalconoids as tubulin-targeting antiproliferative agents.
    Mirzaei H, Shokrzadeh M, Modanloo M, Ziar A, Riazi GH, Emami S.
    Bioorg Chem; 2017 Dec 15; 75():86-98. PubMed ID: 28922629
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
    Lai Q, Wang Y, Wang R, Lai W, Tang L, Tao Y, Liu Y, Zhang R, Huang L, Xiang H, Zeng S, Gou L, Chen H, Yao Y, Yang J.
    Eur J Med Chem; 2018 Aug 05; 156():162-179. PubMed ID: 30006162
    [Abstract] [Full Text] [Related]

  • 15. Tubulin Inhibitors Binding to Colchicine-Site: A Review from 2015 to 2019.
    Xia LY, Zhang YL, Yang R, Wang ZC, Lu YD, Wang BZ, Zhu HL.
    Curr Med Chem; 2020 Aug 05; 27(40):6787-6814. PubMed ID: 31580244
    [Abstract] [Full Text] [Related]

  • 16. Structure of a benzylidene derivative of 9(10H)-anthracenone in complex with tubulin provides a rationale for drug design.
    Cheng J, Wu Y, Wang Y, Wang C, Wang Y, Wu C, Zeng S, Yu Y, Chen Q.
    Biochem Biophys Res Commun; 2018 Jan 01; 495(1):185-188. PubMed ID: 29102632
    [Abstract] [Full Text] [Related]

  • 17. Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin.
    Sun K, Sun Z, Zhao F, Shan G, Meng Q.
    Future Med Chem; 2021 May 01; 13(9):839-858. PubMed ID: 33821673
    [Abstract] [Full Text] [Related]

  • 18. Fragment based group QSAR and molecular dynamics mechanistic studies on arylthioindole derivatives targeting the α-β interfacial site of human tubulin.
    Tyagi C, Gupta A, Goyal S, Dhanjal J, Grover A.
    BMC Genomics; 2014 May 01; 15 Suppl 9(Suppl 9):S3. PubMed ID: 25521775
    [Abstract] [Full Text] [Related]

  • 19. Anti-tubulin agents of natural origin: Targeting taxol, vinca, and colchicine binding domains.
    Naaz F, Haider MR, Shafi S, Yar MS.
    Eur J Med Chem; 2019 Jun 01; 171():310-331. PubMed ID: 30953881
    [Abstract] [Full Text] [Related]

  • 20. The interaction of the B-ring of colchicine with alpha-tubulin: a novel footprinting approach.
    Chaudhuri AR, Seetharamalu P, Schwarz PM, Hausheer FH, Ludueña RF.
    J Mol Biol; 2000 Nov 10; 303(5):679-92. PubMed ID: 11061968
    [Abstract] [Full Text] [Related]


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