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219 related items for PubMed ID: 2965704

  • 1. Biochemical and thrombolytic properties of a low molecular weight form (comprising Leu144 through Leu411) of recombinant single-chain urokinase-type plasminogen activator.
    Lijnen HR, Nelles L, Holmes WE, Collen D.
    J Biol Chem; 1988 Apr 25; 263(12):5594-8. PubMed ID: 2965704
    [Abstract] [Full Text] [Related]

  • 2. Characterization of a recombinant chimeric plasminogen activator with enhanced fibrin binding.
    Jiao J, Yu M, Ru B.
    Biochim Biophys Acta; 2001 Apr 07; 1546(2):399-405. PubMed ID: 11295444
    [Abstract] [Full Text] [Related]

  • 3. Characterization of a recombinant chimeric plasminogen activator composed of a fibrin fragment-D-dimer-specific humanized monoclonal antibody and a truncated single-chain urokinase.
    Vandamme AM, Dewerchin M, Lijnen HR, Bernar H, Bulens F, Nelles L, Collen D.
    Eur J Biochem; 1992 Apr 01; 205(1):139-46. PubMed ID: 1313361
    [Abstract] [Full Text] [Related]

  • 4. Characterization of a chimeric plasminogen activator consisting of a single-chain Fv fragment derived from a fibrin fragment D-dimer-specific antibody and a truncated single-chain urokinase.
    Holvoet P, Laroche Y, Lijnen HR, Van Cauwenberge R, Demarsin E, Brouwers E, Matthyssens G, Collen D.
    J Biol Chem; 1991 Oct 15; 266(29):19717-24. PubMed ID: 1918077
    [Abstract] [Full Text] [Related]

  • 5. Characterization of a fusion protein consisting of amino acids 1 to 263 of tissue-type plasminogen activator and amino acids 144 to 411 of urokinase-type plasminogen activator.
    Nelles L, Lijnen HR, Collen D, Holmes WE.
    J Biol Chem; 1987 Aug 05; 262(22):10855-62. PubMed ID: 2956260
    [Abstract] [Full Text] [Related]

  • 6. Biochemical properties of recombinant single-chain urokinase-type plasminogen activator mutants with deletion of Asn2 through Phe157 and/or substitution of Cys279 with Ala.
    Lijnen HR, Li XK, Nelles L, Hu MH, Collen D.
    Eur J Biochem; 1992 Apr 15; 205(2):701-9. PubMed ID: 1533368
    [Abstract] [Full Text] [Related]

  • 7. Characterization of recombinant human single chain urokinase-type plasminogen activator mutants produced by site-specific mutagenesis of lysine 158.
    Nelles L, Lijnen HR, Collen D, Holmes WE.
    J Biol Chem; 1987 Apr 25; 262(12):5682-9. PubMed ID: 3106341
    [Abstract] [Full Text] [Related]

  • 8. Thrombolytic and pharmacokinetic properties of a recombinant chimeric plasminogen activator consisting of a fibrin fragment D-dimer specific humanized monoclonal antibody and a truncated single-chain urokinase.
    Dewerchin M, Vandamme AM, Holvoet P, De Cock F, Lemmens G, Lijnen HR, Stassen JM, Collen D.
    Thromb Haemost; 1992 Aug 03; 68(2):170-9. PubMed ID: 1412163
    [Abstract] [Full Text] [Related]

  • 9. Structural and functional characterization of mutants of recombinant single-chain urokinase-type plasminogen activator obtained by site-specific mutagenesis of Lys158, Ile159 and Ile160.
    Lijnen HR, Nelles L, Van Hoef B, Demarsin E, Collen D.
    Eur J Biochem; 1988 Nov 15; 177(3):575-82. PubMed ID: 2973984
    [Abstract] [Full Text] [Related]

  • 10. Enhancement of clot lysis in vitro and in vivo with a bispecific monoclonal antibody directed against human fibrin and against urokinase-type plasminogen activator.
    Kurokawa T, Iwasa S, Kakinuma A, Stassen JM, Lijnen HR, Collen D.
    Thromb Haemost; 1991 Dec 02; 66(6):684-93. PubMed ID: 1796414
    [Abstract] [Full Text] [Related]

  • 11. Biochemical characterization of single-chain chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody and single-chain urokinase.
    Holvoet P, Laroche Y, Lijnen HR, Van Hoef B, Brouwers E, De Cock F, Lauwereys M, Gansemans Y, Collen D.
    Eur J Biochem; 1992 Dec 15; 210(3):945-52. PubMed ID: 1483477
    [Abstract] [Full Text] [Related]

  • 12. Effect of fibrin-targeting on clot lysis with urokinase-type plasminogen activator.
    Lijnen HR, Dewerchin M, De Cock F, Collen D.
    Thromb Res; 1990 Feb 01; 57(3):333-42. PubMed ID: 2107593
    [Abstract] [Full Text] [Related]

  • 13. A monoclonal antibody specific for two-chain urokinase-type plasminogen activator. Application to the study of the mechanism of clot lysis with single-chain urokinase-type plasminogen activator in plasma.
    Declerck PJ, Lijnen HR, Verstreken M, Moreau H, Collen D.
    Blood; 1990 May 01; 75(9):1794-800. PubMed ID: 1691934
    [Abstract] [Full Text] [Related]

  • 14. Purification and characterization of a novel low molecular weight form of single-chain urokinase-type plasminogen activator.
    Stump DC, Lijnen HR, Collen D.
    J Biol Chem; 1986 Dec 25; 261(36):17120-6. PubMed ID: 3097021
    [Abstract] [Full Text] [Related]

  • 15. Biochemical properties of recombinant mutants of nonglycosylated single chain urokinase-type plasminogen activator.
    Li XK, Lijnen HR, Nelles L, Hu MH, Collen D.
    Biochim Biophys Acta; 1992 Sep 04; 1159(1):37-43. PubMed ID: 1390910
    [Abstract] [Full Text] [Related]

  • 16. Effect of chemical conjugation of recombinant single-chain urokinase-type plasminogen activator with monoclonal antiplatelet antibodies on platelet aggregation and on plasma clot lysis in vitro and in vivo.
    Dewerchin M, Lijnen HR, Stassen JM, De Cock F, Quertermous T, Ginsberg MH, Plow EF, Collen D.
    Blood; 1991 Aug 15; 78(4):1005-18. PubMed ID: 1831057
    [Abstract] [Full Text] [Related]

  • 17. Functional properties of a recombinant chimeric protein with combined thrombin inhibitory and plasminogen-activating potential.
    Lijnen HR, Wnendt S, Schneider J, Janocha E, Van Hoef B, Collen D, Steffens GJ.
    Eur J Biochem; 1995 Nov 15; 234(1):350-7. PubMed ID: 8529664
    [Abstract] [Full Text] [Related]

  • 18. Biochemical properties of conjugates of urokinase-type plasminogen activator with a monoclonal antibody specific for cross-linked fibrin.
    Dewerchin M, Lijnen HR, Van Hoef B, De Cock F, Collen D.
    Eur J Biochem; 1989 Oct 20; 185(1):141-9. PubMed ID: 2530085
    [Abstract] [Full Text] [Related]

  • 19. Pharmacokinetic and thrombolytic properties of chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody fused to single-chain urokinase.
    Holvoet P, Laroche Y, Stassen JM, Lijnen HR, Van Hoef B, De Cock F, Van Houtven A, Gansemans Y, Matthyssens G, Collen D.
    Blood; 1993 Feb 01; 81(3):696-703. PubMed ID: 8427962
    [Abstract] [Full Text] [Related]

  • 20. Comparative thrombolytic properties of single-chain forms of urokinase-type plasminogen activator.
    Stump DC, Stassen JM, Demarsin E, Collen D.
    Blood; 1987 Feb 01; 69(2):592-6. PubMed ID: 3099862
    [Abstract] [Full Text] [Related]

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