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Journal Abstract Search

476 related items for PubMed ID: 29669855

  • 1. Squalene epoxidase drives NAFLD-induced hepatocellular carcinoma and is a pharmaceutical target.
    Liu D, Wong CC, Fu L, Chen H, Zhao L, Li C, Zhou Y, Zhang Y, Xu W, Yang Y, Wu B, Cheng G, Lai PB, Wong N, Sung JJY, Yu J.
    Sci Transl Med; 2018 Apr 18; 10(437):. PubMed ID: 29669855
    [Abstract] [Full Text] [Related]

  • 2. Squalene epoxidase (SQLE) promotes the growth and migration of the hepatocellular carcinoma cells.
    Sui Z, Zhou J, Cheng Z, Lu P.
    Tumour Biol; 2015 Aug 18; 36(8):6173-9. PubMed ID: 25787749
    [Abstract] [Full Text] [Related]

  • 3. Squalene Epoxidase Induces Nonalcoholic Steatohepatitis Via Binding to Carbonic Anhydrase III and is a Therapeutic Target.
    Liu D, Wong CC, Zhou Y, Li C, Chen H, Ji F, Go MYY, Wang F, Su H, Wei H, Cai Z, Wong N, Wong VWS, Yu J.
    Gastroenterology; 2021 Jun 18; 160(7):2467-2482.e3. PubMed ID: 33647280
    [Abstract] [Full Text] [Related]

  • 4. Squalene epoxidase promotes hepatocellular carcinoma development by activating STRAP transcription and TGF-β/SMAD signalling.
    Zhang Z, Wu W, Jiao H, Chen Y, Ji X, Cao J, Yin F, Yin W.
    Br J Pharmacol; 2023 Jun 18; 180(12):1562-1581. PubMed ID: 36581319
    [Abstract] [Full Text] [Related]

  • 5. Squalene epoxidase-induced cholesteryl ester accumulation promotes nasopharyngeal carcinoma development by activating PI3K/AKT signaling.
    Li L, Zhang Q, Wang X, Li Y, Xie H, Chen X.
    Cancer Sci; 2020 Jul 18; 111(7):2275-2283. PubMed ID: 32314495
    [Abstract] [Full Text] [Related]

  • 6. High Squalene Epoxidase in Tumors Predicts Worse Survival in Patients With Hepatocellular Carcinoma: Integrated Bioinformatic Analysis on NAFLD and HCC.
    Shen T, Lu Y, Zhang Q.
    Cancer Control; 2020 Jul 18; 27(1):1073274820914663. PubMed ID: 32216563
    [Abstract] [Full Text] [Related]

  • 7. Targeting squalene epoxidase restores anti-PD-1 efficacy in metabolic dysfunction-associated steatohepatitis-induced hepatocellular carcinoma.
    Wen J, Zhang X, Wong CC, Zhang Y, Pan Y, Zhou Y, Cheung AH, Liu Y, Ji F, Kang X, Liu D, Yu J.
    Gut; 2024 Nov 11; 73(12):2023-2036. PubMed ID: 38744443
    [Abstract] [Full Text] [Related]

  • 8. Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy.
    Hong Z, Liu T, Wan L, Fa P, Kumar P, Cao Y, Prasad CB, Qiu Z, Liu J, Wang H, Li Z, Wang QE, Guo P, Guo D, Yilmaz AS, Lu L, Papandreou I, Jacob NK, Yan C, Zhang X, She QB, Ma Z, Zhang J.
    Cancer Res; 2022 Apr 01; 82(7):1298-1312. PubMed ID: 35045984
    [Abstract] [Full Text] [Related]

  • 9. Molecular profiling of nonalcoholic fatty liver disease-associated hepatocellular carcinoma using SB transposon mutagenesis.
    Kodama T, Yi J, Newberg JY, Tien JC, Wu H, Finegold MJ, Kodama M, Wei Z, Tamura T, Takehara T, Johnson RL, Jenkins NA, Copeland NG.
    Proc Natl Acad Sci U S A; 2018 Oct 30; 115(44):E10417-E10426. PubMed ID: 30327349
    [Abstract] [Full Text] [Related]

  • 10. Bifidobacterium pseudolongum-generated acetate suppresses non-alcoholic fatty liver disease-associated hepatocellular carcinoma.
    Song Q, Zhang X, Liu W, Wei H, Liang W, Zhou Y, Ding Y, Ji F, Ho-Kwan Cheung A, Wong N, Yu J.
    J Hepatol; 2023 Dec 30; 79(6):1352-1365. PubMed ID: 37459922
    [Abstract] [Full Text] [Related]

  • 11. Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis.
    Li C, Wang Y, Liu D, Wong CC, Coker OO, Zhang X, Liu C, Zhou Y, Liu Y, Kang W, To KF, Sung JJ, Yu J.
    Gut; 2022 Nov 30; 71(11):2253-2265. PubMed ID: 35232776
    [Abstract] [Full Text] [Related]

  • 12. Inhibition of squalene epoxidase linking with PI3K/AKT signaling pathway suppresses endometrial cancer.
    Ma L, Huang W, Liang X, Bai G, Wang X, Jiang H, Xin Y, Hu L, Chen X, Liu C.
    Cancer Sci; 2023 Sep 30; 114(9):3595-3607. PubMed ID: 37438885
    [Abstract] [Full Text] [Related]

  • 13. Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1-mediated MAPK signaling.
    He L, Li H, Pan C, Hua Y, Peng J, Zhou Z, Zhao Y, Lin M.
    Cancer Commun (Lond); 2021 Aug 30; 41(8):726-746. PubMed ID: 34268906
    [Abstract] [Full Text] [Related]

  • 14. O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress.
    Xu W, Zhang X, Wu JL, Fu L, Liu K, Liu D, Chen GG, Lai PB, Wong N, Yu J.
    J Hepatol; 2017 Aug 30; 67(2):310-320. PubMed ID: 28347804
    [Abstract] [Full Text] [Related]

  • 15. Identifying squalene epoxidase as a metabolic vulnerability in high-risk osteosarcoma using an artificial intelligence-derived prognostic index.
    Wang Y, Ma X, Xu E, Huang Z, Yang C, Zhu K, Dong Y, Zhang C.
    Clin Transl Med; 2024 Feb 30; 14(2):e1586. PubMed ID: 38372422
    [Abstract] [Full Text] [Related]

  • 16. TUBB4B is a novel therapeutic target in non-alcoholic fatty liver disease-associated hepatocellular carcinoma.
    Yang Z, Gao S, Wong CC, Liu W, Chen H, Shang H, Wu ZY, Xu L, Zhang X, Wong N, Kuang M, Yu J.
    J Pathol; 2023 May 30; 260(1):71-83. PubMed ID: 36787097
    [Abstract] [Full Text] [Related]

  • 17. Squalene epoxidase promotes the chemoresistance of colorectal cancer via (S)-2,3-epoxysqualene-activated NF-κB.
    Liu Q, Zhang Y, Li H, Gao H, Zhou Y, Luo D, Shan Z, Yang Y, Weng J, Li Q, Yang W, Li X.
    Cell Commun Signal; 2024 May 18; 22(1):278. PubMed ID: 38762737
    [Abstract] [Full Text] [Related]

  • 18. MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer.
    Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson MT, Schmitz W, Wach S, Krebs M, Hartmann E, Puhr M, Müller A, Spahn M, Seitz AK, Frank T, Marouf H, Büchel G, Eckstein M, Kübler H, Eilers M, Saar M, Junker K, Röhrig F, Kneitz B, Rosenfeldt MT, Schulze A.
    Nat Commun; 2021 Aug 20; 12(1):5066. PubMed ID: 34417456
    [Abstract] [Full Text] [Related]

  • 19. Reduction of Squalene Epoxidase by Cholesterol Accumulation Accelerates Colorectal Cancer Progression and Metastasis.
    Jun SY, Brown AJ, Chua NK, Yoon JY, Lee JJ, Yang JO, Jang I, Jeon SJ, Choi TI, Kim CH, Kim NS.
    Gastroenterology; 2021 Mar 20; 160(4):1194-1207.e28. PubMed ID: 32946903
    [Abstract] [Full Text] [Related]

  • 20. Antifungal agent Terbinafine restrains tumor growth in preclinical models of hepatocellular carcinoma via AMPK-mTOR axis.
    Zhang EB, Zhang X, Wang K, Zhang F, Chen TW, Ma N, Ni QZ, Wang YK, Zheng QW, Cao HJ, Xia J, Zhu B, Xu S, Ding X, Wang X, Li Z, Cheng S, Xie D, Li JJ.
    Oncogene; 2021 Aug 20; 40(34):5302-5313. PubMed ID: 34247189
    [Abstract] [Full Text] [Related]

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