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124 related items for PubMed ID: 2967076

  • 1. Inhibition of thymidylate synthase in intact L1210 cells by ara-C, daunomycin, hydroxyurea and 3,4-dihydroxybenzylamine.
    FitzGerald GB, Ratliff J, Wick MM.
    Anticancer Drug Des; 1987 Apr; 1(4):281-9. PubMed ID: 2967076
    [Abstract] [Full Text] [Related]

  • 2. Comparison of the inhibitory effects of hydroxyurea, 5-fluorodeoxyuridine, 3,4-dihydroxybenzylamine, and methotrexate on human squamous cell carcinoma.
    FitzGerald GB, Wick MM.
    J Invest Dermatol; 1987 Jan; 88(1):66-70. PubMed ID: 2947954
    [Abstract] [Full Text] [Related]

  • 3. Sequential inhibitory effects of antitumor agents related to levodopa and dopamine upon DNA synthetic enzymes.
    Fitzgerald GB, Wick MM.
    Biochem Pharmacol; 1986 Jan 15; 35(2):271-5. PubMed ID: 3510622
    [Abstract] [Full Text] [Related]

  • 4. Increased activation of 1-beta-D-arabinofuranosylcytosine by hydroxyurea in L1210 cells.
    Walsh CT, Craig RW, Agarwal RP.
    Cancer Res; 1980 Sep 15; 40(9):3286-92. PubMed ID: 7427943
    [Abstract] [Full Text] [Related]

  • 5. The effects of inhibitors of DNA biosynthesis on the cytotoxicity of 6-thioguanine.
    Lee SH, Sartorelli AC.
    Cancer Biochem Biophys; 1981 Sep 15; 5(3):189-94. PubMed ID: 6455192
    [Abstract] [Full Text] [Related]

  • 6. Role of methylenetetrahydrofolate depletion in methotrexate-mediated intracellular thymidylate synthesis inhibition in cultured L1210 cells.
    Bunni M, Doig MT, Donato H, Kesavan V, Priest DG.
    Cancer Res; 1988 Jun 15; 48(12):3398-404. PubMed ID: 3370638
    [Abstract] [Full Text] [Related]

  • 7. Rapid determination of thymidylate synthase activity and its inhibition in intact L1210 leukemia cells in vitro.
    Yalowich JC, Kalman TI.
    Biochem Pharmacol; 1985 Jul 01; 34(13):2319-24. PubMed ID: 3160352
    [Abstract] [Full Text] [Related]

  • 8. Morphologic differences in leukemic cells (L1210) exposed to 1-beta-D-arabinofuranosylcytosine and daunorubicin.
    Iwasaki H, Aoyama H, Ueda T, Uchida M, Nakamura T.
    Anticancer Res; 1992 Jul 01; 12(3):941-7. PubMed ID: 1622152
    [Abstract] [Full Text] [Related]

  • 9. Cytotoxicity of 5-fluoro-5'-O-nitro-2'-deoxyuridine, a new fluorinated pyrimidine derivative, in L1210 cultures.
    Roberts D, Franklin P, Odom G, Peck C, Chwang TL.
    Mol Pharmacol; 1982 Nov 01; 22(3):760-5. PubMed ID: 6218391
    [Abstract] [Full Text] [Related]

  • 10. Regulation of thymidylate synthetase in mouse leukemia cells (L1210).
    Rode W, Scanlon KJ, Moroson BA, Bertino JR.
    J Biol Chem; 1980 Feb 25; 255(4):1305-11. PubMed ID: 6965493
    [Abstract] [Full Text] [Related]

  • 11. Enhancement by hemin of the sensitivity of K562 human leukemic cells to 1-beta-D-arabinofuranosylcytosine.
    Okabe-Kado J, Hayashi M, Honma Y, Hozumi M.
    Cancer Res; 1986 Mar 25; 46(3):1239-43. PubMed ID: 3455882
    [Abstract] [Full Text] [Related]

  • 12. bcl-2 modulation of apoptosis induced by anticancer drugs: resistance to thymidylate stress is independent of classical resistance pathways.
    Fisher TC, Milner AE, Gregory CD, Jackman AL, Aherne GW, Hartley JA, Dive C, Hickman JA.
    Cancer Res; 1993 Jul 15; 53(14):3321-6. PubMed ID: 8324744
    [Abstract] [Full Text] [Related]

  • 13. Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells.
    Minford J, Kerrigan D, Nichols M, Shackney S, Zwelling LA.
    Cancer Res; 1984 Dec 15; 44(12 Pt 1):5583-93. PubMed ID: 6208999
    [Abstract] [Full Text] [Related]

  • 14. Biochemical and cytokinetic modulation of L1210 and HL-60 cells by hydroxyurea and effect on 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity.
    Rauscher F, Cadman E.
    Cancer Res; 1983 Jun 15; 43(6):2688-93. PubMed ID: 6189585
    [Abstract] [Full Text] [Related]

  • 15. Combination effects of Ara-C and 5-fluorodeoxyuridine against leukemia cells in vitro and in mice.
    Rauko P, Bauer W, Horvath Z, Höchtl T, Saiko P, Karl D, Schott H, Fritzer-Szekeres M, Novotny L, Szekeres T.
    Anticancer Res; 2003 Jun 15; 23(5A):3841-6. PubMed ID: 14666686
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of ribonucleotide reductase by a new class of isoindole derivatives: drug synergism with cytarabine (Ara-C) and induction of cellular apoptosis.
    Nandy P, Lien EJ, Avramis VI.
    Anticancer Res; 1999 Jun 15; 19(3A):1625-33. PubMed ID: 10470093
    [Abstract] [Full Text] [Related]

  • 17. Interconversion of tetrahydrofolate cofactors to dihydrofolate induced by trimetrexate after suppression of thymidylate synthase by fluorodeoxyuridine in L1210 leukemia cells.
    Seither RL, Rape TJ, Goldman ID.
    Biochem Pharmacol; 1992 Jun 23; 43(12):2647-54. PubMed ID: 1385949
    [Abstract] [Full Text] [Related]

  • 18. BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.
    Gibbs DD, Theti DS, Wood N, Green M, Raynaud F, Valenti M, Forster MD, Mitchell F, Bavetsias V, Henderson E, Jackman AL.
    Cancer Res; 2005 Dec 15; 65(24):11721-8. PubMed ID: 16357184
    [Abstract] [Full Text] [Related]

  • 19. Allosteric interaction of components of the replitase complex is responsible for enzyme cross-inhibition.
    Plucinski TM, Fager RS, Reddy GP.
    Mol Pharmacol; 1990 Jul 15; 38(1):114-20. PubMed ID: 1695315
    [Abstract] [Full Text] [Related]

  • 20. Thymidylate synthetase as target enzyme for the inhibitory activity of 5-substituted 2'-deoxyuridines on mouse leukemia L1210 cell growth.
    De Clercq E, Balzarini J, Torrence PF, Mertes MP, Schmidt CL, Shugar D, Barr PJ, Jones AS, Verhelst G, Walker RT.
    Mol Pharmacol; 1981 Mar 15; 19(2):321-30. PubMed ID: 7231392
    [No Abstract] [Full Text] [Related]

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