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Journal Abstract Search

831 related items for PubMed ID: 29673981

  • 1. Synthesis and evaluation of new 2-chloro-4-aminopyrimidine and 2,6-dimethyl-4-aminopyrimidine derivatives as tubulin polymerization inhibitors.
    Xu S, An B, Li Y, Luo X, Li X, Jia X.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1769-1775. PubMed ID: 29673981
    [Abstract] [Full Text] [Related]

  • 2. Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines.
    Huo XS, Jian XE, Ou-Yang J, Chen L, Yang F, Lv DX, You WW, Rao JJ, Zhao PL.
    Eur J Med Chem; 2021 Aug 05; 220():113449. PubMed ID: 33895499
    [Abstract] [Full Text] [Related]

  • 3. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 4. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F, Yu LZ, Diao PC, Jian XE, Zhou MF, Jiang CS, You WW, Ma WF, Zhao PL.
    Bioorg Chem; 2019 Nov 01; 92():103260. PubMed ID: 31525523
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT, Shi TQ, Zhu HL, Liu CH.
    Bioorg Med Chem; 2019 Feb 01; 27(3):502-515. PubMed ID: 30606674
    [Abstract] [Full Text] [Related]

  • 7. Anti-proliferative potential of triphenyl substituted pyrimidines against MDA-MB-231, HCT-116 and HT-29 cancer cell lines.
    Ranjan Dwivedi A, Kumar V, Kaur H, Kumar N, Prakash Yadav R, Poduri R, Baranwal S, Kumar V.
    Bioorg Med Chem Lett; 2020 Oct 15; 30(20):127468. PubMed ID: 32768647
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R, Zhang S, Huang M, Guo Z, Li L, Li M, Wu L, Guan Q, Zhang W.
    Bioorg Chem; 2021 Oct 15; 115():105220. PubMed ID: 34352709
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
    [Abstract] [Full Text] [Related]

  • 10. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Jan 20; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and biological evaluation of novel benzodiazepine derivatives as anticancer agents through inhibition of tubulin polymerization in vitro and in vivo.
    Pang Y, Lin H, Ou C, Cao Y, An B, Yan J, Li X.
    Eur J Med Chem; 2019 Nov 15; 182():111670. PubMed ID: 31499359
    [Abstract] [Full Text] [Related]

  • 13. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 15; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 14. Design and synthesis of novel imidazole-chalcone derivatives as microtubule protein polymerization inhibitors to treat cervical cancer and reverse cisplatin resistance.
    Liu Z, Yang Z, Ablise M.
    Bioorg Chem; 2024 Jun 15; 147():107310. PubMed ID: 38583249
    [Abstract] [Full Text] [Related]

  • 15. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F, He CP, Diao PC, Hong KH, Rao JJ, Zhao PL.
    Bioorg Med Chem Lett; 2019 Jan 01; 29(1):22-27. PubMed ID: 30448234
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties.
    Diao PC, Li Q, Hu MJ, Ma YF, You WW, Hong KH, Zhao PL.
    Eur J Med Chem; 2017 Jul 07; 134():110-118. PubMed ID: 28410492
    [Abstract] [Full Text] [Related]

  • 17. Design and synthesis of pyrazole-oxindole conjugates targeting tubulin polymerization as new anticancer agents.
    Kamal A, Shaik AB, Jain N, Kishor C, Nagabhushana A, Supriya B, Bharath Kumar G, Chourasiya SS, Suresh Y, Mishra RK, Addlagatta A.
    Eur J Med Chem; 2015 Mar 06; 92():501-13. PubMed ID: 25599948
    [Abstract] [Full Text] [Related]

  • 18. Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor.
    Ameri A, Khodarahmi G, Forootanfar H, Hassanzadeh F, Hakimelahi GH.
    Chem Biodivers; 2018 Mar 06; 15(3):e1700518. PubMed ID: 29292595
    [Abstract] [Full Text] [Related]

  • 19. Structure-activity relationships and antiproliferative effects of 1,2,3,4-4H-quinoxaline derivatives as tubulin polymerization inhibitors.
    Liang T, Zhou X, Lu L, Dong H, Zhang Y, Xu Y, Qi J, Zhang Y, Wang J.
    Bioorg Chem; 2021 May 06; 110():104793. PubMed ID: 33770673
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis, biological evaluation and molecular docking studies of new chalcone derivatives containing diaryl ether moiety as potential anticancer agents and tubulin polymerization inhibitors.
    Wang G, Liu W, Gong Z, Huang Y, Li Y, Peng Z.
    Bioorg Chem; 2020 Jan 06; 95():103565. PubMed ID: 31927336
    [Abstract] [Full Text] [Related]

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