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Journal Abstract Search

269 related items for PubMed ID: 29687639

  • 1. Modification, Biological Evaluation and SAR Studies of Novel 1H-Pyrazol Derivatives Containing N,N'-Disubstituted Urea Moiety as Potential Anti-melanoma Agents.
    Ruan BF, Lin MX, Shao Q, Wang TH, Zhang Q, Dong YL, Bu CN, Xu HJ, Zhou BG, Li QS.
    Chem Biodivers; 2018 Jun; 15(6):e1700504. PubMed ID: 29687639
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis and biological evaluation of novel 5-phenyl-1H-pyrazole derivatives as potential BRAF(V600E) inhibitors.
    Wang SF, Zhu YL, Zhu PT, Makawana JA, Zhang YL, Zhao MY, Lv PC, Zhu HL.
    Bioorg Med Chem; 2014 Nov 01; 22(21):6201-8. PubMed ID: 25267006
    [Abstract] [Full Text] [Related]

  • 3. Synthesis of 1H-pyrazole-1-carboxamide derivatives and their antiproliferative activity against melanoma cell line.
    El-Gamal MI, Sim TB, Hong JH, Cho JH, Yoo KH, Oh CH.
    Arch Pharm (Weinheim); 2011 Mar 01; 344(3):197-204. PubMed ID: 21384419
    [Abstract] [Full Text] [Related]

  • 4. Identification of novel 3,5-diarylpyrazoline derivatives containing salicylamide moiety as potential anti-melanoma agents.
    Li QS, Lv XH, Zhang YB, Dong JJ, Zhou WP, Yang Y, Zhu HL.
    Bioorg Med Chem Lett; 2012 Nov 01; 22(21):6596-601. PubMed ID: 23025996
    [Abstract] [Full Text] [Related]

  • 5. Design and biological evaluation of novel triaryl pyrazoline derivatives with dioxane moiety for selective BRAFV600E inhibition.
    Li HL, Su MM, Xu YJ, Xu C, Yang YS, Zhu HL.
    Eur J Med Chem; 2018 Jul 15; 155():725-735. PubMed ID: 29940463
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  • 7. Synthesis, biological evaluation of novel 4,5-dihydro-2H-pyrazole 2-hydroxyphenyl derivatives as BRAF inhibitors.
    Liu JJ, Zhang H, Sun J, Wang ZC, Yang YS, Li DD, Zhang F, Gong HB, Zhu HL.
    Bioorg Med Chem; 2012 Oct 15; 20(20):6089-96. PubMed ID: 22985957
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  • 9. Design, synthesis, and biological evaluation of pyrazole derivatives containing acetamide bond as potential BRAFV600E inhibitors.
    Wang CR, Wang ZF, Shi L, Wang ZC, Zhu HL.
    Bioorg Med Chem Lett; 2018 Aug 01; 28(14):2382-2390. PubMed ID: 29934244
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, biological evaluation and 3D-QSAR study of novel 4,5-dihydro-1H-pyrazole thiazole derivatives as BRAF(V⁶⁰⁰E) inhibitors.
    Zhao MY, Yin Y, Yu XW, Sangani CB, Wang SF, Lu AM, Yang LF, Lv PC, Jiang MG, Zhu HL.
    Bioorg Med Chem; 2015 Jan 01; 23(1):46-54. PubMed ID: 25496804
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  • 11. Design, synthesis, cytotoxicity, HuTopoIIα inhibitory activity and molecular docking studies of pyrazole derivatives as potential anticancer agents.
    Alam R, Wahi D, Singh R, Sinha D, Tandon V, Grover A, Rahisuddin.
    Bioorg Chem; 2016 Dec 01; 69():77-90. PubMed ID: 27744115
    [Abstract] [Full Text] [Related]

  • 12. Discovery of N-(benzyloxy)-1,3-diphenyl-1H-pyrazole-4-carboxamide derivatives as potential antiproliferative agents by inhibiting MEK.
    Lv XH, Ren ZL, Zhou BG, Li QS, Chu MJ, Liu DH, Mo K, Zhang LS, Yao XK, Cao HQ.
    Bioorg Med Chem; 2016 Oct 01; 24(19):4652-4659. PubMed ID: 27515719
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  • 14. Modification, biological evaluation and 3D QSAR studies of novel 2-(1,3-diaryl- 4,5-dihydro-1H-pyrazol-5-yl)phenol derivatives as inhibitors of B-Raf kinase.
    Yang YS, Zhang F, Tang DJ, Yang YH, Zhu HL.
    PLoS One; 2014 Oct 01; 9(5):e95702. PubMed ID: 24827980
    [Abstract] [Full Text] [Related]

  • 15. Novel pyrazole-5-carboxamide and pyrazole-pyrimidine derivatives: synthesis and anticancer activity.
    Shi JB, Tang WJ, Qi XB, Li R, Liu XH.
    Eur J Med Chem; 2015 Jan 27; 90():889-96. PubMed ID: 25554922
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  • 17. Design, synthesis, biological evaluation and molecular docking studies of novel benzofuran-pyrazole derivatives as anticancer agents.
    Abd El-Karim SS, Anwar MM, Mohamed NA, Nasr T, Elseginy SA.
    Bioorg Chem; 2015 Dec 27; 63():1-12. PubMed ID: 26368040
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  • 20. Design, synthesis, and antiproliferative activity of 3,4-diarylpyrazole-1-carboxamide derivatives against melanoma cell line.
    El-Gamal MI, Choi HS, Cho HG, Hong JH, Yoo KH, Oh CH.
    Arch Pharm (Weinheim); 2011 Nov 27; 344(11):745-54. PubMed ID: 21954060
    [Abstract] [Full Text] [Related]

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