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Journal Abstract Search

477 related items for PubMed ID: 29699922

  • 1. Hit discovery of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase, GuaB2, inhibitors.
    Sahu NU, Singh V, Ferraris DM, Rizzi M, Kharkar PS.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1714-1718. PubMed ID: 29699922
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  • 3. Synthesis and Structure-Activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH.
    Singh V, Pacitto A, Donini S, Ferraris DM, Boros S, Illyés E, Szokol B, Rizzi M, Blundell TL, Ascher DB, Pato J, Mizrahi V.
    Eur J Med Chem; 2019 Jul 15; 174():309-329. PubMed ID: 31055147
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  • 5. Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis.
    Park Y, Pacitto A, Bayliss T, Cleghorn LA, Wang Z, Hartman T, Arora K, Ioerger TR, Sacchettini J, Rizzi M, Donini S, Blundell TL, Ascher DB, Rhee K, Breda A, Zhou N, Dartois V, Jonnala SR, Via LE, Mizrahi V, Epemolu O, Stojanovski L, Simeons F, Osuna-Cabello M, Ellis L, MacKenzie CJ, Smith AR, Davis SH, Murugesan D, Buchanan KI, Turner PA, Huggett M, Zuccotto F, Rebollo-Lopez MJ, Lafuente-Monasterio MJ, Sanz O, Diaz GS, Lelièvre J, Ballell L, Selenski C, Axtman M, Ghidelli-Disse S, Pflaumer H, Bösche M, Drewes G, Freiberg GM, Kurnick MD, Srikumaran M, Kempf DJ, Green SR, Ray PC, Read K, Wyatt P, Barry CE, Boshoff HI.
    ACS Infect Dis; 2017 Jan 13; 3(1):18-33. PubMed ID: 27704782
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  • 6. Fragment-Based Approach to Targeting Inosine-5'-monophosphate Dehydrogenase (IMPDH) from Mycobacterium tuberculosis.
    Trapero A, Pacitto A, Singh V, Sabbah M, Coyne AG, Mizrahi V, Blundell TL, Ascher DB, Abell C.
    J Med Chem; 2018 Apr 12; 61(7):2806-2822. PubMed ID: 29547284
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  • 8. Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents.
    Chacko S, Boshoff HIM, Singh V, Ferraris DM, Gollapalli DR, Zhang M, Lawson AP, Pepi MJ, Joachimiak A, Rizzi M, Mizrahi V, Cuny GD, Hedstrom L.
    J Med Chem; 2018 Jun 14; 61(11):4739-4756. PubMed ID: 29746130
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  • 9. Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen.
    Cox JA, Mugumbate G, Del Peral LV, Jankute M, Abrahams KA, Jervis P, Jackenkroll S, Perez A, Alemparte C, Esquivias J, Lelièvre J, Ramon F, Barros D, Ballell L, Besra GS.
    Sci Rep; 2016 Dec 16; 6():38986. PubMed ID: 27982051
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  • 12. Covalent inactivation of Mycobacterium thermoresistibile inosine-5'-monophosphate dehydrogenase (IMPDH).
    Trapero A, Pacitto A, Chan DS, Abell C, Blundell TL, Ascher DB, Coyne AG.
    Bioorg Med Chem Lett; 2020 Jan 15; 30(2):126792. PubMed ID: 31757668
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  • 18. Inosine monophosphate dehydrogenase (IMPDH) as a target in drug discovery.
    Shu Q, Nair V.
    Med Res Rev; 2008 Mar 15; 28(2):219-32. PubMed ID: 17480004
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