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Journal Abstract Search

213 related items for PubMed ID: 29714141

  • 1. Blocking IL-6/GP130 Signaling Inhibits Cell Viability/Proliferation, Glycolysis, and Colony Forming Activity in Human Pancreatic Cancer Cells.
    Chen X, Tian J, Su GH, Lin J.
    Curr Cancer Drug Targets; 2019; 19(5):417-427. PubMed ID: 29714141
    [Abstract] [Full Text] [Related]

  • 2. Down-regulating IL-6/GP130 targets improved the anti-tumor effects of 5-fluorouracil in colon cancer.
    Li S, Tian J, Zhang H, Zhou S, Wang X, Zhang L, Yang J, Zhang Z, Ji Z.
    Apoptosis; 2018 Jun; 23(5-6):356-374. PubMed ID: 29777330
    [Abstract] [Full Text] [Related]

  • 3. Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy.
    Wu X, Cao Y, Xiao H, Li C, Lin J.
    Mol Cancer Ther; 2016 Nov; 15(11):2609-2619. PubMed ID: 27535971
    [Abstract] [Full Text] [Related]

  • 4. Bazedoxifene as a novel GP130 inhibitor for Colon Cancer therapy.
    Wei J, Ma L, Lai YH, Zhang R, Li H, Li C, Lin J.
    J Exp Clin Cancer Res; 2019 Feb 08; 38(1):63. PubMed ID: 30736824
    [Abstract] [Full Text] [Related]

  • 5. Bazedoxifene is a novel IL-6/GP130 inhibitor for treating triple-negative breast cancer.
    Tian J, Chen X, Fu S, Zhang R, Pan L, Cao Y, Wu X, Xiao H, Lin HJ, Lo HW, Zhang Y, Lin J.
    Breast Cancer Res Treat; 2019 Jun 08; 175(3):553-566. PubMed ID: 30852762
    [Abstract] [Full Text] [Related]

  • 6. Repositioning Bazedoxifene as a novel IL-6/GP130 signaling antagonist for human rhabdomyosarcoma therapy.
    Xiao H, Bid HK, Chen X, Wu X, Wei J, Bian Y, Zhao C, Li H, Li C, Lin J.
    PLoS One; 2017 Jun 08; 12(7):e0180297. PubMed ID: 28672024
    [Abstract] [Full Text] [Related]

  • 7. Bazedoxifene exhibits growth suppressive activity by targeting interleukin-6/glycoprotein 130/signal transducer and activator of transcription 3 signaling in hepatocellular carcinoma.
    Ma H, Yan D, Wang Y, Shi W, Liu T, Zhao C, Huo S, Duan J, Tao J, Zhai M, Luo P, Guo J, Tian L, Mageta L, Jou D, Zhang C, Li C, Lin J, Lv J, Li S, Lin L.
    Cancer Sci; 2019 Mar 08; 110(3):950-961. PubMed ID: 30648776
    [Abstract] [Full Text] [Related]

  • 8. Growth-suppressive activity of raloxifene on liver cancer cells by targeting IL-6/GP130 signaling.
    Wang Y, Ma H, Zhao C, Liu T, Yan D, Jou D, Li H, Zhang C, Lü J, Li C, Lin J, Li S, Lin L.
    Oncotarget; 2017 May 16; 8(20):33683-33693. PubMed ID: 28430601
    [Abstract] [Full Text] [Related]

  • 9. Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.
    Thilakasiri P, Huynh J, Poh AR, Tan CW, Nero TL, Tran K, Parslow AC, Afshar-Sterle S, Baloyan D, Hannan NJ, Buchert M, Scott AM, Griffin MD, Hollande F, Parker MW, Putoczki TL, Ernst M, Chand AL.
    EMBO Mol Med; 2019 Apr 16; 11(4):. PubMed ID: 30885958
    [Abstract] [Full Text] [Related]

  • 10. Raloxifene inhibits pancreatic adenocarcinoma growth by interfering with ERβ and IL-6/gp130/STAT3 signaling.
    Pozios I, Seel NN, Hering NA, Hartmann L, Liu V, Camaj P, Müller MH, Lee LD, Bruns CJ, Kreis ME, Seeliger H.
    Cell Oncol (Dordr); 2021 Feb 16; 44(1):167-177. PubMed ID: 32940862
    [Abstract] [Full Text] [Related]

  • 11. Blocking interleukin-6 signaling inhibits cell viability/proliferation, glycolysis, and colony forming activity of human medulloblastoma cells.
    Chen X, Wei J, Li C, Pierson CR, Finlay JL, Lin J.
    Int J Oncol; 2018 Feb 16; 52(2):571-578. PubMed ID: 29207075
    [Abstract] [Full Text] [Related]

  • 12. Discovery of bazedoxifene analogues targeting glycoprotein 130.
    Song D, Yu W, Ren Y, Zhu J, Wan C, Cai G, Guo J, Zhang W, Kong L.
    Eur J Med Chem; 2020 Aug 01; 199():112375. PubMed ID: 32388278
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of GP130/STAT3 and EMT by combined bazedoxifene and paclitaxel treatment in ovarian cancer.
    Park SA, Kim LK, Park HM, Kim HJ, Heo TH.
    Oncol Rep; 2022 Mar 01; 47(3):. PubMed ID: 35029286
    [Abstract] [Full Text] [Related]

  • 14. Gp130 is expressed in pancreatic cancer and can be targeted by the small inhibitor molecule SC144.
    Pozios I, Hering NA, Guenzler E, Arndt M, Elezkurtaj S, Knösel T, Bruns CJ, Margonis GA, Beyer K, Seeliger H.
    J Cancer Res Clin Oncol; 2023 Jan 01; 149(1):271-280. PubMed ID: 36495330
    [Abstract] [Full Text] [Related]

  • 15. Bazedoxifene Inhibits Cell Viability, Colony-Forming Activity, and Cell Migration in Human Non-Small Cell Lung Cancer Cells and Improves the Treatment Efficacy of Paclitaxel and Gemcitabine.
    Huang Y, Lin J, Fu X, Li L, Fu S.
    Clin Respir J; 2024 Aug 01; 18(8):e13822. PubMed ID: 39152779
    [Abstract] [Full Text] [Related]

  • 16. Bazedoxifene, a GP130 Inhibitor, Modulates EMT Signaling and Exhibits Antitumor Effects in HPV-Positive Cervical Cancer.
    Kim L, Park SA, Park H, Kim H, Heo TH.
    Int J Mol Sci; 2021 Aug 13; 22(16):. PubMed ID: 34445405
    [Abstract] [Full Text] [Related]

  • 17. Sonic hedgehog inhibitors prevent colitis-associated cancer via orchestrated mechanisms of IL-6/gp130 inhibition, 15-PGDH induction, Bcl-2 abrogation, and tumorsphere inhibition.
    Kangwan N, Kim YJ, Han YM, Jeong M, Park JM, Go EJ, Hahm KB.
    Oncotarget; 2016 Feb 16; 7(7):7667-82. PubMed ID: 26716648
    [Abstract] [Full Text] [Related]

  • 18. Blocking Interleukin-6 and Interleukin-8 Signaling Inhibits Cell Viability, Colony-forming Activity, and Cell Migration in Human Triple-negative Breast Cancer and Pancreatic Cancer Cells.
    Fu S, Lin J.
    Anticancer Res; 2018 Nov 16; 38(11):6271-6279. PubMed ID: 30396947
    [Abstract] [Full Text] [Related]

  • 19. Drug design targeting protein-protein interactions (PPIs) using multiple ligand simultaneous docking (MLSD) and drug repositioning: discovery of raloxifene and bazedoxifene as novel inhibitors of IL-6/GP130 interface.
    Li H, Xiao H, Lin L, Jou D, Kumari V, Lin J, Li C.
    J Med Chem; 2014 Feb 13; 57(3):632-41. PubMed ID: 24456369
    [Abstract] [Full Text] [Related]

  • 20. Inhibition of interleukin-6-transsignaling via gp130-Fc in hemorrhagic shock and sepsis.
    Mees ST, Toellner S, Marx K, Faendrich F, Kallen KJ, Schroeder J, Haier J, Kahlke V.
    J Surg Res; 2009 Dec 13; 157(2):235-42. PubMed ID: 19589542
    [Abstract] [Full Text] [Related]

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