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436 related items for PubMed ID: 2973984

  • 1. Structural and functional characterization of mutants of recombinant single-chain urokinase-type plasminogen activator obtained by site-specific mutagenesis of Lys158, Ile159 and Ile160.
    Lijnen HR, Nelles L, Van Hoef B, Demarsin E, Collen D.
    Eur J Biochem; 1988 Nov 15; 177(3):575-82. PubMed ID: 2973984
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  • 2. Characterization of recombinant human single chain urokinase-type plasminogen activator mutants produced by site-specific mutagenesis of lysine 158.
    Nelles L, Lijnen HR, Collen D, Holmes WE.
    J Biol Chem; 1987 Apr 25; 262(12):5682-9. PubMed ID: 3106341
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  • 3. Plasminogen activation with single-chain urokinase-type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser740----Ala) and plasmin-resistant scu-PA (Lys158----Glu).
    Lijnen HR, Van Hoef B, Nelles L, Collen D.
    J Biol Chem; 1990 Mar 25; 265(9):5232-6. PubMed ID: 1969415
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  • 4. Biochemical properties of recombinant single-chain urokinase-type plasminogen activator mutants with deletion of Asn2 through Phe157 and/or substitution of Cys279 with Ala.
    Lijnen HR, Li XK, Nelles L, Hu MH, Collen D.
    Eur J Biochem; 1992 Apr 15; 205(2):701-9. PubMed ID: 1533368
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  • 5. Enzymatic properties of single-chain and two-chain forms of a Lys158----Glu158 mutant of urokinase-type plasminogen activator.
    Lijnen HR, Van Hoef B, Nelles L, Holmes WE, Collen D.
    Eur J Biochem; 1988 Feb 15; 172(1):185-8. PubMed ID: 2894309
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  • 10. Characterization of the intrinsic fibrinolytic properties of pro-urokinase through a study of plasmin-resistant mutant forms produced by site-specific mutagenesis of lysine(158).
    Gurewich V, Pannell R, Broeze RJ, Mao J.
    J Clin Invest; 1988 Dec 15; 82(6):1956-62. PubMed ID: 2974047
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  • 13. Biochemical properties of conjugates of urokinase-type plasminogen activator with a monoclonal antibody specific for cross-linked fibrin.
    Dewerchin M, Lijnen HR, Van Hoef B, De Cock F, Collen D.
    Eur J Biochem; 1989 Oct 20; 185(1):141-9. PubMed ID: 2530085
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  • 14. Mechanism of the enhanced intrinsic activity of single-chain urokinase-type plasminogen activator during ongoing fibrinolysis.
    Fleury V, Lijnen HR, Anglés-Cano E.
    J Biol Chem; 1993 Sep 05; 268(25):18554-9. PubMed ID: 8103046
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  • 16. Properties of chimeric (tissue-type/urokinase-type) plasminogen activators obtained by fusion at the plasmin cleavage site.
    Colucci M, Cavallo LG, Agnelli G, Mele A, Bürgi R, Heim J, Semeraro N.
    Thromb Haemost; 1993 May 03; 69(5):466-72. PubMed ID: 8391727
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  • 18. Expression and characterization of clustered charge-to-alanine mutants of low M(r) single-chain urokinase-type plasminogen activator.
    Ueshima S, Holvoet P, Lijnen HR, Nelles L, Seghers V, Collen D.
    Thromb Haemost; 1994 Jan 03; 71(1):134-40. PubMed ID: 8165632
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  • 19. Characterization of thrombin- and plasmin-resistant mutants of recombinant human single chain urokinase-type plasminogen activator.
    Eguchi Y, Sakata Y, Matsuda M, Osada H, Numao N, Ohmori M, Kondo K.
    J Biochem; 1990 Jul 03; 108(1):72-9. PubMed ID: 2146258
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