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Journal Abstract Search

131 related items for PubMed ID: 2974022

  • 1. Different pathways for deoxyguanosine toxicity in T-lymphocytes of various developmental stages.
    Scharenberg JG, Rijkers GT, Spaapen LJ, Toebes EA, Rijksen G, Duran M, Staal GE, Zegers BJ.
    Int J Immunopharmacol; 1988; 10(6):675-86. PubMed ID: 2974022
    [Abstract] [Full Text] [Related]

  • 2. Mechanisms of deoxyguanosine lymphotoxicity. Human thymocytes, but not peripheral blood lymphocytes accumulate deoxy-GTP in conditions simulating purine nucleoside phosphorylase deficiency.
    Fairbanks LD, Taddeo A, Duley JA, Simmonds HA.
    J Immunol; 1990 Jan 15; 144(2):485-91. PubMed ID: 2104895
    [Abstract] [Full Text] [Related]

  • 3. Functional and mechanistic studies on the toxicity of deoxyguanosine for the in vitro proliferation and differentiation of human peripheral blood B lymphocytes.
    Scharenberg JG, Spaapen LJ, Rijkers GT, Duran M, Staal GE, Zegers BJ.
    Eur J Immunol; 1986 Apr 15; 16(4):381-7. PubMed ID: 3084280
    [Abstract] [Full Text] [Related]

  • 4. The effect of deoxyguanosine on human lymphocyte function. II. Analysis of the interference with B lymphocyte differentiation in vitro.
    Spaapen LJ, Rijkers GT, Staal GE, Rijksen G, Duran M, Stoop JW, Zegers BJ.
    J Immunol; 1984 May 15; 132(5):2318-23. PubMed ID: 6425400
    [Abstract] [Full Text] [Related]

  • 5. The effect of deoxyguanosine on human lymphocyte function. I. Analysis of the interference with lymphocyte proliferation in vitro.
    Spaapen LJ, Rijkers GT, Staal GE, Rijksen G, Wadman SK, Stoop JW, Zegers BJ.
    J Immunol; 1984 May 15; 132(5):2311-7. PubMed ID: 6425399
    [Abstract] [Full Text] [Related]

  • 6. Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP.
    Duan DS, Nagashima T, Hoshino T, Waldman F, Pawlak K, Sadee W.
    Biochem J; 1990 Jun 15; 268(3):725-31. PubMed ID: 2114100
    [Abstract] [Full Text] [Related]

  • 7. 2'-deoxyguanosine toxicity for B and mature T lymphoid cell lines is mediated by guanine ribonucleotide accumulation.
    Sidi Y, Mitchell BS.
    J Clin Invest; 1984 Nov 15; 74(5):1640-8. PubMed ID: 6334099
    [Abstract] [Full Text] [Related]

  • 8.
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  • 9. Effects of purine nucleoside phosphorylase deficiency on thymocyte development.
    Papinazath T, Min W, Sujiththa S, Cohen A, Ackerley C, Roifman CM, Grunebaum E.
    J Allergy Clin Immunol; 2011 Oct 15; 128(4):854-863.e1. PubMed ID: 21868080
    [Abstract] [Full Text] [Related]

  • 10. Mechanisms of deoxyguanosine toxicity for human T and B lymphocytes.
    Scharenberg JG, Spaapen LJ, Rijkers GT, Wadman SK, Staal GE, Zegers BJ.
    Adv Exp Med Biol; 1986 Oct 15; 195 Pt B():191-9. PubMed ID: 3094325
    [No Abstract] [Full Text] [Related]

  • 11. Potent orally bioavailable purine nucleoside phosphorylase inhibitor BCX-4208 induces apoptosis in B- and T-lymphocytes--a novel treatment approach for autoimmune diseases, organ transplantation and hematologic malignancies.
    Bantia S, Parker C, Upshaw R, Cunningham A, Kotian P, Kilpatrick JM, Morris P, Chand P, Babu YS.
    Int Immunopharmacol; 2010 Jul 15; 10(7):784-90. PubMed ID: 20399911
    [Abstract] [Full Text] [Related]

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  • 13. Effect of 9-benzyl-9-deazaguanine, a potent inhibitor of purine nucleoside phosphorylase, on the cytotoxicity and metabolism of 6-thio-2'-deoxyguanosine.
    Parker WB, Allan PW, Niwas S, Montgomery JA, Bennett LL.
    Cancer Res; 1994 Apr 01; 54(7):1742-5. PubMed ID: 8137289
    [Abstract] [Full Text] [Related]

  • 14. Expression of deoxyadenosine and deoxyguanosine toxicity at different stages of lymphocyte activation.
    Scharenberg JG, Rijkers GT, Toebes EA, Staal GE, Zegers BJ.
    Scand J Immunol; 1988 Jul 01; 28(1):87-93. PubMed ID: 3135585
    [Abstract] [Full Text] [Related]

  • 15. Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)--a novel potent and orally active immunosuppressive agent.
    Bantia S, Miller PJ, Parker CD, Ananth SL, Horn LL, Kilpatrick JM, Morris PE, Hutchison TL, Montgomery JA, Sandhu JS.
    Int Immunopharmacol; 2001 Jun 01; 1(6):1199-210. PubMed ID: 11407314
    [Abstract] [Full Text] [Related]

  • 16. A purine nucleoside phosphorylase (PNP) inhibitor induces apoptosis via caspase-3-like protease activity in MOLT-4 T cells.
    Posmantur R, Wang KK, Nath R, Gilbertsen RB.
    Immunopharmacology; 1997 Oct 01; 37(2-3):231-44. PubMed ID: 9403342
    [Abstract] [Full Text] [Related]

  • 17. Deoxyadenosine triphosphate as a mediator of deoxyguanosine toxicity in cultured T lymphoblasts.
    Mann GJ, Fox RM.
    J Clin Invest; 1986 Nov 01; 78(5):1261-9. PubMed ID: 3490493
    [Abstract] [Full Text] [Related]

  • 18. Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor--BCX-1777.
    Bantia S, Ananth SL, Parker CD, Horn LL, Upshaw R.
    Int Immunopharmacol; 2003 Jun 01; 3(6):879-87. PubMed ID: 12781704
    [Abstract] [Full Text] [Related]

  • 19. Metabolism of deoxynucleosides by lymphocytes in long-term culture deficient in different purine enzymes.
    Simmonds HA, Goday A, Morris GS, Brolsma MF.
    Biochem Pharmacol; 1984 Mar 01; 33(5):763-70. PubMed ID: 6424679
    [Abstract] [Full Text] [Related]

  • 20. Analysis of purine nucleoside phosphorylase from human T and non-T lymphocytes of different maturation stages.
    Spaapen LJ, Rijksen G, Staal GE, Zegers BJ.
    Clin Biochem; 1983 Feb 01; 16(1):54-6. PubMed ID: 6407781
    [Abstract] [Full Text] [Related]

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