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Journal Abstract Search

244 related items for PubMed ID: 29751233

  • 1. New developments in non-quinolone-based antibiotics for the inhibiton of bacterial gyrase and topoisomerase IV.
    Badshah SL, Ullah A.
    Eur J Med Chem; 2018 May 25; 152():393-400. PubMed ID: 29751233
    [Abstract] [Full Text] [Related]

  • 2. Novel 3-fluoro-6-methoxyquinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV.
    Mitton-Fry MJ, Brickner SJ, Hamel JC, Barham R, Brennan L, Casavant JM, Ding X, Finegan S, Hardink J, Hoang T, Huband MD, Maloney M, Marfat A, McCurdy SP, McLeod D, Subramanyam C, Plotkin M, Reilly U, Schafer J, Stone GG, Uccello DP, Wisialowski T, Yoon K, Zaniewski R, Zook C.
    Bioorg Med Chem Lett; 2017 Aug 01; 27(15):3353-3358. PubMed ID: 28610977
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  • 3. Discovery of aminopiperidine based potent & novel topoisomerase inhibitor with broad spectrum anti-bacterial activity.
    Desai J, Patel B, Panchal N, Gite A, Darji B, Viswanathan K, Trivedi J, Vyas P, Pawar V, Giri P, S S, Sharma R, Jain M, Iyer P, Kumar S.
    Bioorg Med Chem Lett; 2024 Oct 01; 111():129911. PubMed ID: 39067715
    [Abstract] [Full Text] [Related]

  • 4. Discovery of dual GyrB/ParE inhibitors active against Gram-negative bacteria.
    Ho SY, Wang W, Ng FM, Wong YX, Poh ZY, Tan SWE, Ang SH, Liew SS, Joyner Wong YS, Tan Y, Poulsen A, Pendharkar V, Sangthongpitag K, Manchester J, Basarab G, Hill J, Keller TH, Cherian J.
    Eur J Med Chem; 2018 Sep 05; 157():610-621. PubMed ID: 30125722
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  • 5. 1,3-Dioxane-Linked Bacterial Topoisomerase Inhibitors with Enhanced Antibacterial Activity and Reduced hERG Inhibition.
    Li L, Okumu AA, Nolan S, English A, Vibhute S, Lu Y, Hervert-Thomas K, Seffernick JT, Azap L, Cole SL, Shinabarger D, Koeth LM, Lindert S, Yalowich JC, Wozniak DJ, Mitton-Fry MJ.
    ACS Infect Dis; 2019 Jul 12; 5(7):1115-1128. PubMed ID: 31041863
    [Abstract] [Full Text] [Related]

  • 6. Design, green one-pot synthesis and molecular docking study of novel N,N-bis(cyanoacetyl)hydrazines and bis-coumarins as effective inhibitors of DNA gyrase and topoisomerase IV.
    Metwally NH, Abdallah SO, Mohsen MMA.
    Bioorg Chem; 2020 Apr 12; 97():103672. PubMed ID: 32145481
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of novel 2-aminobenzothiazole derivatives as potential antimicrobial agents with dual DNA gyrase/topoisomerase IV inhibition.
    Ismail MMF, Abdulwahab HG, Nossier ES, El Menofy NG, Abdelkhalek BA.
    Bioorg Chem; 2020 Jan 12; 94():103437. PubMed ID: 31812260
    [Abstract] [Full Text] [Related]

  • 8. New dual ATP-competitive inhibitors of bacterial DNA gyrase and topoisomerase IV active against ESKAPE pathogens.
    Durcik M, Nyerges Á, Skok Ž, Skledar DG, Trontelj J, Zidar N, Ilaš J, Zega A, Cruz CD, Tammela P, Welin M, Kimbung YR, Focht D, Benek O, Révész T, Draskovits G, Szili PÉ, Daruka L, Pál C, Kikelj D, Mašič LP, Tomašič T.
    Eur J Med Chem; 2021 Mar 05; 213():113200. PubMed ID: 33524686
    [Abstract] [Full Text] [Related]

  • 9. DNA Topoisomerases as Targets for Antibacterial Agents.
    Hiasa H.
    Methods Mol Biol; 2018 Mar 05; 1703():47-62. PubMed ID: 29177732
    [Abstract] [Full Text] [Related]

  • 10. Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics.
    Alt S, Mitchenall LA, Maxwell A, Heide L.
    J Antimicrob Chemother; 2011 Sep 05; 66(9):2061-9. PubMed ID: 21693461
    [Abstract] [Full Text] [Related]

  • 11. Design and synthesis of ciprofloxacin-sulfonamide hybrids to manipulate ciprofloxacin pharmacological qualities: Potency and side effects.
    Ibrahim NM, Fahim SH, Hassan M, Farag AE, Georgey HH.
    Eur J Med Chem; 2022 Jan 15; 228():114021. PubMed ID: 34871841
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and antibacterial evaluation of new quinoline-1,3,4-oxadiazole and quinoline-1,2,4-triazole hybrids as potential inhibitors of DNA gyrase and topoisomerase IV.
    Hofny HA, Mohamed MFA, Gomaa HAM, Abdel-Aziz SA, Youssif BGM, El-Koussi NA, Aboraia AS.
    Bioorg Chem; 2021 Jul 15; 112():104920. PubMed ID: 33910078
    [Abstract] [Full Text] [Related]

  • 13. Virtual Screening Approach and Investigation of Structure-Activity Relationships To Discover Novel Bacterial Topoisomerase Inhibitors Targeting Gram-Positive and Gram-Negative Pathogens.
    Magarò G, Prati F, Garofalo B, Corso G, Furlotti G, Apicella C, Mangano G, D'Atanasio N, Robinson D, Di Giorgio FP, Ombrato R.
    J Med Chem; 2019 Aug 22; 62(16):7445-7472. PubMed ID: 31276392
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  • 19. Synthesis and structure-activity relationship studies of 4-arylthiosemicarbazides as topoisomerase IV inhibitors with Gram-positive antibacterial activity. Search for molecular basis of antibacterial activity of thiosemicarbazides.
    Siwek A, Stączek P, Stefańska J.
    Eur J Med Chem; 2011 Nov 22; 46(11):5717-26. PubMed ID: 21978836
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