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173 related items for PubMed ID: 29772386

  • 1. Novel anticancer hybrids from diazen-1-ium-1,2-diolate nitric oxide donor and ROS inducer plumbagin: Design, synthesis and biological evaluations.
    Bao N, Ou J, Li N, Zou P, Sun J, Chen L.
    Eur J Med Chem; 2018 Jun 25; 154():1-8. PubMed ID: 29772386
    [Abstract] [Full Text] [Related]

  • 2. Novel NO-releasing plumbagin derivatives: Design, synthesis and evaluation of antiproliferative activity.
    Bao N, Ou J, Xu M, Guan F, Shi W, Sun J, Chen L.
    Eur J Med Chem; 2017 Sep 08; 137():88-95. PubMed ID: 28558333
    [Abstract] [Full Text] [Related]

  • 3. Novel anticancer oridonin derivatives possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: Design, synthesis, biological evaluation and nitric oxide release studies.
    Xu S, Wang G, Lin Y, Zhang Y, Pei L, Yao H, Hu M, Qiu Y, Huang Z, Zhang Y, Xu J.
    Bioorg Med Chem Lett; 2016 Jun 15; 26(12):2795-2800. PubMed ID: 27158140
    [Abstract] [Full Text] [Related]

  • 4. Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction.
    Tripathi SK, Rengasamy KRR, Biswal BK.
    Arch Pharm Res; 2020 Feb 15; 43(2):242-256. PubMed ID: 32034669
    [Abstract] [Full Text] [Related]

  • 5. Anticancer phytochemical analogs 37: synthesis, characterization, molecular docking and cytotoxicity of novel plumbagin hydrazones against breast cancer cells.
    Dandawate P, Ahmad A, Deshpande J, Swamy KV, Khan EM, Khetmalas M, Padhye S, Sarkar F.
    Bioorg Med Chem Lett; 2014 Jul 01; 24(13):2900-4. PubMed ID: 24835626
    [Abstract] [Full Text] [Related]

  • 6. Target ROS to induce apoptosis and cell cycle arrest by 5,7-dimethoxy-1,4-naphthoquinone derivative.
    Li K, Wang B, Zheng L, Yang K, Li Y, Hu M, He D.
    Bioorg Med Chem Lett; 2018 Feb 01; 28(3):273-277. PubMed ID: 29305189
    [Abstract] [Full Text] [Related]

  • 7. The natural anticancer agent plumbagin induces potent cytotoxicity in MCF-7 human breast cancer cells by inhibiting a PI-5 kinase for ROS generation.
    Lee JH, Yeon JH, Kim H, Roh W, Chae J, Park HO, Kim DM.
    PLoS One; 2012 Feb 01; 7(9):e45023. PubMed ID: 23028742
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of novel plumbagin derivatives as potent antitumor agents with STAT3 inhibition.
    Li N, Ou J, Bao N, Chen C, Shi Z, Chen L, Sun J.
    Bioorg Chem; 2020 Nov 01; 104():104208. PubMed ID: 32919131
    [Abstract] [Full Text] [Related]

  • 9. Novel juglone and plumbagin 5-O derivatives and their in vitro growth inhibitory activity against apoptosis-resistant cancer cells.
    Fiorito S, Genovese S, Taddeo VA, Mathieu V, Kiss R, Epifano F.
    Bioorg Med Chem Lett; 2016 Jan 15; 26(2):334-337. PubMed ID: 26706169
    [Abstract] [Full Text] [Related]

  • 10. The role of thioredoxin reductase and glutathione reductase in plumbagin-induced, reactive oxygen species-mediated apoptosis in cancer cell lines.
    Hwang GH, Ryu JM, Jeon YJ, Choi J, Han HJ, Lee YM, Lee S, Bae JS, Jung JW, Chang W, Kim LK, Jee JG, Lee MY.
    Eur J Pharmacol; 2015 Oct 15; 765():384-93. PubMed ID: 26341012
    [Abstract] [Full Text] [Related]

  • 11. NG as a novel nitric oxide donor induces apoptosis by increasing reactive oxygen species and inhibiting mitochondrial function in MGC803 cells.
    Liu L, Li T, Tan J, Fu J, Guo Q, Ji H, Zhang Y.
    Int Immunopharmacol; 2014 Nov 15; 23(1):27-36. PubMed ID: 25135879
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of sulfur-containing shikonin oxime derivatives as potential antineoplastic agents.
    Huang G, Zhao HR, Meng QQ, Zhang QJ, Dong JY, Zhu BQ, Li SS.
    Eur J Med Chem; 2018 Jan 01; 143():166-181. PubMed ID: 29174813
    [Abstract] [Full Text] [Related]

  • 13. Cytotoxicity and apoptosis induced by a plumbagin derivative in estrogen positive MCF-7 breast cancer cells.
    Sagar S, Esau L, Moosa B, Khashab NM, Bajic VB, Kaur M.
    Anticancer Agents Med Chem; 2014 Jan 01; 14(1):170-80. PubMed ID: 24164046
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and anticancer activity of some novel 5,6-fused hybrids of juglone based 1,4-naphthoquinones.
    Mallavadhani UV, Prasad CV, Shrivastava S, Naidu VG.
    Eur J Med Chem; 2014 Aug 18; 83():84-91. PubMed ID: 24953027
    [Abstract] [Full Text] [Related]

  • 15. Cytotoxicity of Synthesized 1,4-Naphthoquinone Oxime Derivatives on Selected Human Cancer Cell Lines.
    Zhang Q, Dong J, Cui J, Huang G, Meng Q, Li S.
    Chem Pharm Bull (Tokyo); 2018 Aug 18; 66(6):612-619. PubMed ID: 29863062
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and Investigation of the Role of Benzopyran Dihydropyrimidinone Hybrids in Cell Proliferation, Migration and Tumor Growth.
    Dash AK, Nayak D, Hussain N, Mintoo MJ, Bano S, Katoch A, Mondhe DM, Goswami A, Mukherjee D.
    Anticancer Agents Med Chem; 2019 Aug 18; 19(2):276-288. PubMed ID: 30179143
    [Abstract] [Full Text] [Related]

  • 17. Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells.
    Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL.
    Cancer Lett; 2008 Jan 18; 259(1):82-98. PubMed ID: 18023967
    [Abstract] [Full Text] [Related]

  • 18. Hybrid molecule from O2-(2,4-dinitrophenyl)diazeniumdiolate and oleanolic acid: a glutathione S-transferase π-activated nitric oxide prodrug with selective anti-human hepatocellular carcinoma activity and improved stability.
    Fu J, Liu L, Huang Z, Lai Y, Ji H, Peng S, Tian J, Zhang Y.
    J Med Chem; 2013 Jun 13; 56(11):4641-55. PubMed ID: 23617697
    [Abstract] [Full Text] [Related]

  • 19. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
    [Abstract] [Full Text] [Related]

  • 20. NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS/MAPK-dependent mitochondrial pathway.
    Liu L, Fu J, Li T, Cui R, Ling J, Yu X, Ji H, Zhang Y.
    Eur J Pharmacol; 2012 Sep 15; 691(1-3):61-8. PubMed ID: 22824464
    [Abstract] [Full Text] [Related]

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