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202 related items for PubMed ID: 29775410

  • 1. Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition.
    Parikh VN, Liu J, Shang C, Woods C, Chang AC, Zhao M, Charo DN, Grunwald Z, Huang Y, Seo K, Tsao PS, Bernstein D, Ruiz-Lozano P, Quertermous T, Ashley EA.
    Am J Physiol Heart Circ Physiol; 2018 Aug 01; 315(2):H348-H356. PubMed ID: 29775410
    [Abstract] [Full Text] [Related]

  • 2. Gαi-biased apelin analog protects against isoproterenol-induced myocardial dysfunction in rats.
    Coquerel D, Delile E, Dumont L, Chagnon F, Murza A, Sainsily X, Salvail D, Sarret P, Marsault E, Auger-Messier M, Lesur O.
    Am J Physiol Heart Circ Physiol; 2021 Apr 01; 320(4):H1646-H1656. PubMed ID: 33635165
    [Abstract] [Full Text] [Related]

  • 3. ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.
    Sato T, Sato C, Kadowaki A, Watanabe H, Ho L, Ishida J, Yamaguchi T, Kimura A, Fukamizu A, Penninger JM, Reversade B, Ito H, Imai Y, Kuba K.
    Cardiovasc Res; 2017 Jun 01; 113(7):760-769. PubMed ID: 28371822
    [Abstract] [Full Text] [Related]

  • 4. APJ acts as a dual receptor in cardiac hypertrophy.
    Scimia MC, Hurtado C, Ray S, Metzler S, Wei K, Wang J, Woods CE, Purcell NH, Catalucci D, Akasaka T, Bueno OF, Vlasuk GP, Kaliman P, Bodmer R, Smith LH, Ashley E, Mercola M, Brown JH, Ruiz-Lozano P.
    Nature; 2012 Aug 16; 488(7411):394-8. PubMed ID: 22810587
    [Abstract] [Full Text] [Related]

  • 5. Apelin/APJ system: A bifunctional target for cardiac hypertrophy.
    Lu L, Wu D, Li L, Chen L.
    Int J Cardiol; 2017 Mar 01; 230():164-170. PubMed ID: 27979574
    [Abstract] [Full Text] [Related]

  • 6. In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure.
    Gargalovic P, Wong P, Onorato J, Finlay H, Wang T, Yan M, Crain E, St-Onge S, Héroux M, Bouvier M, Xu C, Chen XQ, Generaux C, Lawrence M, Wexler R, Gordon D.
    Circ Heart Fail; 2021 Mar 01; 14(3):e007351. PubMed ID: 33663236
    [Abstract] [Full Text] [Related]

  • 7. Caveolin-1-Autophagy Pathway Mediated Cardiomyocyte Hypertrophy Induced by Apelin-13.
    Wu D, Xie F, Xiao L, Feng F, Huang S, He L, Liu M, Zhou Q, Li L, Chen L.
    DNA Cell Biol; 2017 Aug 01; 36(8):611-618. PubMed ID: 28537760
    [Abstract] [Full Text] [Related]

  • 8. Endogenous regulation of cardiovascular function by apelin-APJ.
    Charo DN, Ho M, Fajardo G, Kawana M, Kundu RK, Sheikh AY, Finsterbach TP, Leeper NJ, Ernst KV, Chen MM, Ho YD, Chun HJ, Bernstein D, Ashley EA, Quertermous T.
    Am J Physiol Heart Circ Physiol; 2009 Nov 01; 297(5):H1904-13. PubMed ID: 19767528
    [Abstract] [Full Text] [Related]

  • 9. Lactation Is a Risk Factor of Postpartum Heart Failure in Mice with Cardiomyocyte-specific Apelin Receptor (APJ) Overexpression.
    Murata K, Ishida J, Ishimaru T, Mizukami H, Hamada J, Saito C, Fukamizu A.
    J Biol Chem; 2016 May 20; 291(21):11241-51. PubMed ID: 27033703
    [Abstract] [Full Text] [Related]

  • 10. [Sacubitril/valsartan attenuates left ventricular remodeling and improve cardiac function by upregulating apelin/APJ pathway in rats with heart failure].
    Liu HZ, Gao CY, Yuan F, Xu Y, Tian H, Wang SQ, Zhang PF, Shi YN, Wei JJ.
    Zhonghua Xin Xue Guan Bing Za Zhi; 2022 Jul 24; 50(7):690-697. PubMed ID: 35856226
    [Abstract] [Full Text] [Related]

  • 11. In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure.
    Sheikh AY, Chun HJ, Glassford AJ, Kundu RK, Kutschka I, Ardigo D, Hendry SL, Wagner RA, Chen MM, Ali ZA, Yue P, Huynh DT, Connolly AJ, Pelletier MP, Tsao PS, Robbins RC, Quertermous T.
    Am J Physiol Heart Circ Physiol; 2008 Jan 24; 294(1):H88-98. PubMed ID: 17906101
    [Abstract] [Full Text] [Related]

  • 12. Possible involvement of downregulation of the apelin-APJ system in doxorubicin-induced cardiotoxicity.
    Hamada J, Baasanjav A, Ono N, Murata K, Kako K, Ishida J, Fukamizu A.
    Am J Physiol Heart Circ Physiol; 2015 Apr 15; 308(8):H931-41. PubMed ID: 25681427
    [Abstract] [Full Text] [Related]

  • 13. Disruption of actin dynamics regulated by Rho effector mDia1 attenuates pressure overload-induced cardiac hypertrophic responses and exacerbates dysfunction.
    Abe I, Terabayashi T, Hanada K, Kondo H, Teshima Y, Ishii Y, Miyoshi M, Kira S, Saito S, Tsuchimochi H, Shirai M, Yufu K, Arakane M, Daa T, Thumkeo D, Narumiya S, Takahashi N, Ishizaki T.
    Cardiovasc Res; 2021 Mar 21; 117(4):1103-1117. PubMed ID: 32647865
    [Abstract] [Full Text] [Related]

  • 14. Direct effects of apelin on cardiomyocyte contractility and electrophysiology.
    Farkasfalvi K, Stagg MA, Coppen SR, Siedlecka U, Lee J, Soppa GK, Marczin N, Szokodi I, Yacoub MH, Terracciano CM.
    Biochem Biophys Res Commun; 2007 Jun 15; 357(4):889-95. PubMed ID: 17466269
    [Abstract] [Full Text] [Related]

  • 15. Identification of serine 348 on the apelin receptor as a novel regulatory phosphorylation site in apelin-13-induced G protein-independent biased signaling.
    Chen X, Bai B, Tian Y, Du H, Chen J.
    J Biol Chem; 2014 Nov 07; 289(45):31173-87. PubMed ID: 25271156
    [Abstract] [Full Text] [Related]

  • 16. The microRNA-204-5p inhibits APJ signalling and confers resistance to cardiac hypertrophy and dysfunction.
    Gaddam RR, Kim YR, Jacobs JS, Yoon JY, Li Q, Cai A, Shankaiahgari H, London B, Irani K, Vikram A.
    Clin Transl Med; 2022 Jan 07; 12(1):e693. PubMed ID: 35060347
    [Abstract] [Full Text] [Related]

  • 17. Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling.
    Sato T, Kadowaki A, Suzuki T, Ito H, Watanabe H, Imai Y, Kuba K.
    Int J Mol Sci; 2019 Jan 09; 20(2):. PubMed ID: 30634441
    [Abstract] [Full Text] [Related]

  • 18. (3R)‑5,6,7‑trihydroxy‑3‑isopropyl‑3‑methylisochroman‑1‑one attenuates cardiac dysfunction via the apelin/APJ signaling pathway.
    Ding M, Guan L, Zhang C, Yang P, Yang H.
    Mol Med Rep; 2019 Jun 09; 19(6):5007-5014. PubMed ID: 30942406
    [Abstract] [Full Text] [Related]

  • 19. The complex regulation of tanshinone IIA in rats with hypertension-induced left ventricular hypertrophy.
    Pang H, Han B, Yu T, Peng Z.
    PLoS One; 2014 Jun 09; 9(3):e92216. PubMed ID: 24647357
    [Abstract] [Full Text] [Related]

  • 20. Apelin/ELABELA-APJ system in cardiac hypertrophy: Regulatory mechanisms and therapeutic potential.
    Pang B, Jiang YR, Xu JY, Shao DX, Hao LY.
    Eur J Pharmacol; 2023 Jun 15; 949():175727. PubMed ID: 37062502
    [Abstract] [Full Text] [Related]

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