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Journal Abstract Search
329 related items for PubMed ID: 29849119
1. mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy. Seo SU, Woo SM, Lee HS, Kim SH, Min KJ, Kwon TK. Oncogene; 2018 Sep; 37(38):5205-5220. PubMed ID: 29849119 [Abstract] [Full Text] [Related]
2. HSP70 Acetylation Prevents Combined mTORC1/2 Inhibitor and Curcumin Treatment-Induced Apoptosis. Seo SU, Min KJ, Woo SM, Seo JH, Kwon TK. Molecules; 2018 Oct 24; 23(11):. PubMed ID: 30356017 [Abstract] [Full Text] [Related]
4. An mTORC1/2 kinase inhibitor enhances the cytotoxicity of gemtuzumab ozogamicin by activation of lysosomal function. Maimaitili Y, Inase A, Miyata Y, Kitao A, Mizutani Y, Kakiuchi S, Shimono Y, Saito Y, Sonoki T, Minami H, Matsuoka H. Leuk Res; 2018 Nov 24; 74():68-74. PubMed ID: 30300823 [Abstract] [Full Text] [Related]
5. mTOR kinase inhibitor pp242 causes mitophagy terminated by apoptotic cell death in E1A-Ras transformed cells. Gordeev SA, Bykova TV, Zubova SG, Bystrova OA, Martynova MG, Pospelov VA, Pospelova TV. Oncotarget; 2015 Dec 29; 6(42):44905-26. PubMed ID: 26636543 [Abstract] [Full Text] [Related]
6. Pharmacological inhibition of mTORC1 but not mTORC2 protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism through Akt and autophagy induction. Kakiuchi Y, Yurube T, Kakutani K, Takada T, Ito M, Takeoka Y, Kanda Y, Miyazaki S, Kuroda R, Nishida K. Osteoarthritis Cartilage; 2019 Jun 29; 27(6):965-976. PubMed ID: 30716534 [Abstract] [Full Text] [Related]
7. mTOR complex 2 is involved in regulation of Cbl-dependent c-FLIP degradation and sensitivity of TRAIL-induced apoptosis. Zhao L, Yue P, Khuri FR, Sun SY. Cancer Res; 2013 Mar 15; 73(6):1946-57. PubMed ID: 23319802 [Abstract] [Full Text] [Related]
8. PDK1 inhibitor GSK2334470 exerts antitumor activity in multiple myeloma and forms a novel multitargeted combination with dual mTORC1/C2 inhibitor PP242. Yang C, Huang X, Liu H, Xiao F, Wei J, You L, Qian W. Oncotarget; 2017 Jun 13; 8(24):39185-39197. PubMed ID: 28402933 [Abstract] [Full Text] [Related]
11. The dual mTORC1 and mTORC2 inhibitor PP242 shows strong antitumor activity in a pheochromocytoma PC12 cell tumor model. Zhang X, Wang X, Qin L, Xu T, Zhu Z, Zhong S, Zhang M, Shen Z. Urology; 2015 Jan 13; 85(1):273.e1-7. PubMed ID: 25440763 [Abstract] [Full Text] [Related]
12. Therapeutic potential of a dual mTORC1/2 inhibitor for the prevention of posterior capsule opacification: An in vitro study. Feng H, Yang Z, Bai X, Yang M, Fang Y, Zhang X, Guo Q, Ning H. Int J Mol Med; 2018 Apr 13; 41(4):2099-2107. PubMed ID: 29344639 [Abstract] [Full Text] [Related]
13. Selective interference of mTORC1/RAPTOR protects against human disc cellular apoptosis, senescence, and extracellular matrix catabolism with Akt and autophagy induction. Ito M, Yurube T, Kakutani K, Maeno K, Takada T, Terashima Y, Kakiuchi Y, Takeoka Y, Miyazaki S, Kuroda R, Nishida K. Osteoarthritis Cartilage; 2017 Dec 13; 25(12):2134-2146. PubMed ID: 28888905 [Abstract] [Full Text] [Related]
14. Inhibition of JNK-mediated autophagy enhances NSCLC cell sensitivity to mTORC1/2 inhibitors. Jin HO, Hong SE, Park JA, Chang YH, Hong YJ, Park IC, Lee JK. Sci Rep; 2016 Jun 30; 6():28945. PubMed ID: 27358039 [Abstract] [Full Text] [Related]
15. The mTOR Kinase Inhibitor CZ415 Inhibits Human Papillary Thyroid Carcinoma Cell Growth. Li X, Li Z, Song Y, Liu W, Liu Z. Cell Physiol Biochem; 2018 Jun 30; 46(2):579-590. PubMed ID: 29617677 [Abstract] [Full Text] [Related]
16. The antileukemia roles of PP242 alone or in combination with daunorubicin in acute leukemia. Shi F, Yang X, Gong Y, Shi R, Yang X, Naren D, Wu J. Anticancer Drugs; 2015 Apr 30; 26(4):410-21. PubMed ID: 25535978 [Abstract] [Full Text] [Related]
17. PP242 suppresses bladder cancer cell proliferation and migration through deactivating the mammalian target of rapamycin complex 2/AKT1 signaling pathway. Zhang Z, Zhang G, Kong C, Gong D. Mol Med Rep; 2016 Jan 30; 13(1):333-8. PubMed ID: 26548560 [Abstract] [Full Text] [Related]
18. Targeted inhibition of mTORC2 prevents osteosarcoma cell migration and promotes apoptosis. Wang X, Lai P, Zhang Z, Huang M, Wang L, Yin M, Jin D, Zhou R, Bai X. Oncol Rep; 2014 Jul 30; 32(1):382-8. PubMed ID: 24840134 [Abstract] [Full Text] [Related]