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202 related items for PubMed ID: 29850793
1. Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma. Chortis V, Taylor AE, Doig CL, Walsh MD, Meimaridou E, Jenkinson C, Rodriguez-Blanco G, Ronchi CL, Jafri A, Metherell LA, Hebenstreit D, Dunn WB, Arlt W, Foster PA. Endocrinology; 2018 Aug 01; 159(8):2836-2849. PubMed ID: 29850793 [Abstract] [Full Text] [Related]
8. Mitochondrial NAD(P)+ Transhydrogenase: From Molecular Features to Physiology and Disease. Francisco A, Figueira TR, Castilho RF. Antioxid Redox Signal; 2022 May 01; 36(13-15):864-884. PubMed ID: 34155914 [Abstract] [Full Text] [Related]
9. The Contribution of Nicotinamide Nucleotide Transhydrogenase to Peroxide Detoxification Is Dependent on the Respiratory State and Counterbalanced by Other Sources of NADPH in Liver Mitochondria. Ronchi JA, Francisco A, Passos LA, Figueira TR, Castilho RF. J Biol Chem; 2016 Sep 16; 291(38):20173-87. PubMed ID: 27474736 [Abstract] [Full Text] [Related]
11. Mutations in NNT encoding nicotinamide nucleotide transhydrogenase cause familial glucocorticoid deficiency. Meimaridou E, Kowalczyk J, Guasti L, Hughes CR, Wagner F, Frommolt P, Nürnberg P, Mann NP, Banerjee R, Saka HN, Chapple JP, King PJ, Clark AJ, Metherell LA. Nat Genet; 2012 May 27; 44(7):740-2. PubMed ID: 22634753 [Abstract] [Full Text] [Related]
12. NNT reverse mode of operation mediates glucose control of mitochondrial NADPH and glutathione redox state in mouse pancreatic β-cells. Santos LRB, Muller C, de Souza AH, Takahashi HK, Spégel P, Sweet IR, Chae H, Mulder H, Jonas JC. Mol Metab; 2017 Jun 27; 6(6):535-547. PubMed ID: 28580284 [Abstract] [Full Text] [Related]
13. Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R. Gaujoux S, Hantel C, Launay P, Bonnet S, Perlemoine K, Lefèvre L, Guillaud-Bataille M, Beuschlein F, Tissier F, Bertherat J, Rizk-Rabin M, Ragazzon B. PLoS One; 2013 Jun 27; 8(2):e55743. PubMed ID: 23409032 [Abstract] [Full Text] [Related]
14. Loss of β-catenin in adrenocortical cancer cells causes growth inhibition and reversal of epithelial-to-mesenchymal transition. Salomon A, Keramidas M, Maisin C, Thomas M. Oncotarget; 2015 May 10; 6(13):11421-33. PubMed ID: 25823656 [Abstract] [Full Text] [Related]
15. Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure. Smith CD, Schmidt CA, Lin CT, Fisher-Wellman KH, Neufer PD. J Biol Chem; 2020 Nov 27; 295(48):16207-16216. PubMed ID: 32747443 [Abstract] [Full Text] [Related]
17. Lack of NAD(P)+ transhydrogenase activity in patients with primary adrenal insufficiency due to NNT variants. Francisco A, Goler AMY, Navarro CDC, Onder A, Yildiz M, Kendir Demirkol Y, Karademir Yilmaz B, Seven Menevse T, Güran T, Castilho RF. Eur J Endocrinol; 2024 Feb 01; 190(2):130-138. PubMed ID: 38261461 [Abstract] [Full Text] [Related]
18. Toward a pathway-centered approach for the treatment of adrenocortical carcinoma. Bussey KJ, Demeure MJ. Curr Opin Oncol; 2011 Jan 01; 23(1):34-44. PubMed ID: 21045685 [Abstract] [Full Text] [Related]
19. Homeobox A5 activates p53 pathway to inhibit proliferation and promote apoptosis of adrenocortical carcinoma cells by inducing Aldo-Keto reductase family 1 member B10 expression. Chen D, Shen Z, Cheng X, Wang Q, Zhou J, Ren F, Sun Y, Wang H, Huang R. Bioengineered; 2021 Dec 01; 12(1):1964-1975. PubMed ID: 34027794 [Abstract] [Full Text] [Related]