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Journal Abstract Search

191 related items for PubMed ID: 29855181

  • 1. Pyrrolizidine Alkaloid Secondary Pyrrolic Metabolites Construct Multiple Activation Pathways Leading to DNA Adduct Formation and Potential Liver Tumor Initiation.
    Xia Q, He X, Ma L, Chen S, Fu PP.
    Chem Res Toxicol; 2018 Jul 16; 31(7):619-628. PubMed ID: 29855181
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  • 4. Primary and secondary pyrrolic metabolites of pyrrolizidine alkaloids form DNA adducts in human A549 cells.
    He X, Xia Q, Wu Q, Tolleson WH, Lin G, Fu PP.
    Toxicol In Vitro; 2019 Feb 16; 54():286-294. PubMed ID: 30366057
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  • 5. Metabolic formation of DHP-derived DNA adducts from a representative otonecine type pyrrolizidine alkaloid clivorine and the extract of Ligularia hodgsonnii hook.
    Xia Q, Chou MW, Lin G, Fu PP.
    Chem Res Toxicol; 2004 May 16; 17(5):702-8. PubMed ID: 15144228
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  • 6. 7-glutathione pyrrole adduct: a potential DNA reactive metabolite of pyrrolizidine alkaloids.
    Xia Q, Ma L, He X, Cai L, Fu PP.
    Chem Res Toxicol; 2015 Apr 20; 28(4):615-20. PubMed ID: 25768656
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  • 7. 7-Glutathione-pyrrole and 7-cysteine-pyrrole are potential carcinogenic metabolites of pyrrolizidine alkaloids.
    He X, Xia Q, Fu PP.
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2017 Apr 03; 35(2):69-83. PubMed ID: 28418776
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  • 8. 7-cysteine-pyrrole conjugate: A new potential DNA reactive metabolite of pyrrolizidine alkaloids.
    He X, Xia Q, Ma L, Fu PP.
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2016 Apr 03; 34(1):57-76. PubMed ID: 26761716
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  • 9. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
    Wang YP, Yan J, Fu PP, Chou MW.
    Toxicol Lett; 2005 Mar 15; 155(3):411-20. PubMed ID: 15649625
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  • 10. Quantitation of DNA reactive pyrrolic metabolites of senecionine - A carcinogenic pyrrolizidine alkaloid by LC/MS/MS analysis.
    Xia Q, He X, Shi Q, Lin G, Fu PP.
    J Food Drug Anal; 2020 Jan 15; 28(1):167-174. PubMed ID: 31883605
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  • 11. Identification of DNA adducts derived from riddelliine, a carcinogenic pyrrolizidine alkaloid.
    Chou MW, Jian Y, Williams LD, Xia Q, Churchwell M, Doerge DR, Fu PP.
    Chem Res Toxicol; 2003 Sep 15; 16(9):1130-7. PubMed ID: 12971801
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  • 12. Reaction of dehydropyrrolizidine alkaloids with valine and hemoglobin.
    Zhao Y, Wang S, Xia Q, Gamboa da Costa G, Doerge DR, Cai L, Fu PP.
    Chem Res Toxicol; 2014 Oct 20; 27(10):1720-31. PubMed ID: 25211425
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  • 13. Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine.
    Chou MW, Wang YP, Yan J, Yang YC, Beger RD, Williams LD, Doerge DR, Fu PP.
    Toxicol Lett; 2003 Dec 10; 145(3):239-47. PubMed ID: 14580895
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  • 14. 9-Glutathionyl-6,7-dihydro-1-hydroxymethyl-5H-pyrrolizine Is the Major Pyrrolic Glutathione Conjugate of Retronecine-Type Pyrrolizidine Alkaloids in Liver Microsomes and in Rats.
    Chen M, Li L, Zhong D, Shen S, Zheng J, Chen X.
    Chem Res Toxicol; 2016 Feb 15; 29(2):180-9. PubMed ID: 26761523
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  • 15. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, lasiocarpine.
    Xia Q, Chou MW, Edgar JA, Doerge DR, Fu PP.
    Cancer Lett; 2006 Jan 08; 231(1):138-45. PubMed ID: 16356839
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  • 16. Pyrrolizidine alkaloid-derived DNA adducts as a common biological biomarker of pyrrolizidine alkaloid-induced tumorigenicity.
    Xia Q, Zhao Y, Von Tungeln LS, Doerge DR, Lin G, Cai L, Fu PP.
    Chem Res Toxicol; 2013 Sep 16; 26(9):1384-96. PubMed ID: 23937665
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  • 17. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine.
    Xia Q, Yan J, Chou MW, Fu PP.
    Toxicol Lett; 2008 May 05; 178(2):77-82. PubMed ID: 18395999
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  • 18. Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts.
    Yan J, Xia Q, Chou MW, Fu PP.
    Toxicol Ind Health; 2008 Apr 05; 24(3):181-8. PubMed ID: 18842697
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