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435 related items for PubMed ID: 29858187

  • 1. Targeting Rac and Cdc42 GTPases in Cancer.
    Maldonado MDM, Dharmawardhane S.
    Cancer Res; 2018 Jun 15; 78(12):3101-3111. PubMed ID: 29858187
    [Abstract] [Full Text] [Related]

  • 2. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer.
    Humphries-Bickley T, Castillo-Pichardo L, Hernandez-O'Farrill E, Borrero-Garcia LD, Forestier-Roman I, Gerena Y, Blanco M, Rivera-Robles MJ, Rodriguez-Medina JR, Cubano LA, Vlaar CP, Dharmawardhane S.
    Mol Cancer Ther; 2017 May 15; 16(5):805-818. PubMed ID: 28450422
    [Abstract] [Full Text] [Related]

  • 3. A Rac/Cdc42-specific exchange factor, GEFT, induces cell proliferation, transformation, and migration.
    Guo X, Stafford LJ, Bryan B, Xia C, Ma W, Wu X, Liu D, Songyang Z, Liu M.
    J Biol Chem; 2003 Apr 11; 278(15):13207-15. PubMed ID: 12547822
    [Abstract] [Full Text] [Related]

  • 4. The role of Rho GTPases' substrates Rac and Cdc42 in osteoclastogenesis and relevant natural medicinal products study.
    Liu Y, Dou Y, Yan L, Yang X, He B, Kong L, Smith W.
    Biosci Rep; 2020 Jul 31; 40(7):. PubMed ID: 32578854
    [Abstract] [Full Text] [Related]

  • 5. Temporally and spatially coordinated roles for Rho, Rac, Cdc42 and their effectors in growth cone guidance by a physiological electric field.
    Rajnicek AM, Foubister LE, McCaig CD.
    J Cell Sci; 2006 May 01; 119(Pt 9):1723-35. PubMed ID: 16595546
    [Abstract] [Full Text] [Related]

  • 6. Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via alpha-PIX.
    Filipenko NR, Attwell S, Roskelley C, Dedhar S.
    Oncogene; 2005 Sep 01; 24(38):5837-49. PubMed ID: 15897874
    [Abstract] [Full Text] [Related]

  • 7. An essential role for Rac/Cdc42 GTPases in cerebellar granule neuron survival.
    Linseman DA, Laessig T, Meintzer MK, McClure M, Barth H, Aktories K, Heidenreich KA.
    J Biol Chem; 2001 Oct 19; 276(42):39123-31. PubMed ID: 11509562
    [Abstract] [Full Text] [Related]

  • 8. Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3.
    Okamoto H, Takuwa N, Yokomizo T, Sugimoto N, Sakurada S, Shigematsu H, Takuwa Y.
    Mol Cell Biol; 2000 Dec 19; 20(24):9247-61. PubMed ID: 11094076
    [Abstract] [Full Text] [Related]

  • 9. The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade.
    Baird D, Feng Q, Cerione RA.
    Curr Biol; 2005 Jan 11; 15(1):1-10. PubMed ID: 15649357
    [Abstract] [Full Text] [Related]

  • 10. Phospholipase C gamma negatively regulates Rac/Cdc42 activation in antigen-stimulated mast cells.
    El-Sibai M, Backer JM.
    Eur J Immunol; 2007 Jan 11; 37(1):261-70. PubMed ID: 17163445
    [Abstract] [Full Text] [Related]

  • 11. IFN-gamma and STAT1 arrest monocyte migration and modulate RAC/CDC42 pathways.
    Hu Y, Hu X, Boumsell L, Ivashkiv LB.
    J Immunol; 2008 Jun 15; 180(12):8057-65. PubMed ID: 18523269
    [Abstract] [Full Text] [Related]

  • 12. Cdc42 Signaling Pathway Inhibition as a Therapeutic Target in Ras- Related Cancers.
    Aguilar BJ, Zhou H, Lu Q.
    Curr Med Chem; 2017 Jun 15; 24(32):3485-3507. PubMed ID: 28571533
    [Abstract] [Full Text] [Related]

  • 13. Targeting Rac and Cdc42 GEFs in Metastatic Cancer.
    Maldonado MDM, Medina JI, Velazquez L, Dharmawardhane S.
    Front Cell Dev Biol; 2020 Jun 15; 8():201. PubMed ID: 32322580
    [Abstract] [Full Text] [Related]

  • 14. Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species.
    Diebold BA, Fowler B, Lu J, Dinauer MC, Bokoch GM.
    J Biol Chem; 2004 Jul 02; 279(27):28136-42. PubMed ID: 15123662
    [Abstract] [Full Text] [Related]

  • 15. Vav regulates activation of Rac but not Cdc42 during FcgammaR-mediated phagocytosis.
    Patel JC, Hall A, Caron E.
    Mol Biol Cell; 2002 Apr 02; 13(4):1215-26. PubMed ID: 11950933
    [Abstract] [Full Text] [Related]

  • 16. Vav2 as a Rac-GDP/GTP exchange factor responsible for the nectin-induced, c-Src- and Cdc42-mediated activation of Rac.
    Kawakatsu T, Ogita H, Fukuhara T, Fukuyama T, Minami Y, Shimizu K, Takai Y.
    J Biol Chem; 2005 Feb 11; 280(6):4940-7. PubMed ID: 15485841
    [Abstract] [Full Text] [Related]

  • 17. Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation.
    Royal I, Lamarche-Vane N, Lamorte L, Kaibuchi K, Park M.
    Mol Biol Cell; 2000 May 11; 11(5):1709-25. PubMed ID: 10793146
    [Abstract] [Full Text] [Related]

  • 18. Rac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cells.
    Baugher PJ, Krishnamoorthy L, Price JE, Dharmawardhane SF.
    Breast Cancer Res; 2005 May 11; 7(6):R965-74. PubMed ID: 16280046
    [Abstract] [Full Text] [Related]

  • 19. Clostridium difficile toxin B, an inhibitor of the small GTPases Rho, Rac and Cdc42, influences spiral ganglion neurite outgrowth.
    Brors D, Aletsee C, Dazert S, Huverstuhl J, Ryan AF, Bodmer D.
    Acta Otolaryngol; 2003 Jan 11; 123(1):20-5. PubMed ID: 12625568
    [Abstract] [Full Text] [Related]

  • 20. Cdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1.
    Norden PR, Kim DJ, Barry DM, Cleaver OB, Davis GE.
    PLoS One; 2016 Jan 11; 11(1):e0147758. PubMed ID: 26812085
    [Abstract] [Full Text] [Related]

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