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Journal Abstract Search

276 related items for PubMed ID: 29883944

  • 1. Gallic acid targets acute myeloid leukemia via Akt/mTOR-dependent mitochondrial respiration inhibition.
    Gu R, Zhang M, Meng H, Xu D, Xie Y.
    Biomed Pharmacother; 2018 Sep; 105():491-497. PubMed ID: 29883944
    [Abstract] [Full Text] [Related]

  • 2. Targeting nasopharyngeal carcinoma by artesunate through inhibiting Akt/mTOR and inducing oxidative stress.
    Li Q, Ni W, Deng Z, Liu M, She L, Xie Q.
    Fundam Clin Pharmacol; 2017 Jun; 31(3):301-310. PubMed ID: 28078787
    [Abstract] [Full Text] [Related]

  • 3. The simultaneous inhibition of the mTOR and MAPK pathways with Gnetin-C induces apoptosis in acute myeloid leukemia.
    Espinoza JL, Elbadry MI, Taniwaki M, Harada K, Trung LQ, Nakagawa N, Takami A, Ishiyama K, Yamauchi T, Takenaka K, Nakao S.
    Cancer Lett; 2017 Aug 01; 400():127-136. PubMed ID: 28456658
    [Abstract] [Full Text] [Related]

  • 4. Emodin and Its Combination with Cytarabine Induce Apoptosis in Resistant Acute Myeloid Leukemia Cells in Vitro and in Vivo.
    Chen Y, Gan D, Huang Q, Luo X, Lin D, Hu J.
    Cell Physiol Biochem; 2018 Aug 01; 48(5):2061-2073. PubMed ID: 30099447
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of mTOR kinase as a therapeutic target for acute myeloid leukemia.
    Tabe Y, Tafuri A, Sekihara K, Yang H, Konopleva M.
    Expert Opin Ther Targets; 2017 Jul 01; 21(7):705-714. PubMed ID: 28537457
    [Abstract] [Full Text] [Related]

  • 6. The Complexity of Targeting PI3K-Akt-mTOR Signalling in Human Acute Myeloid Leukaemia: The Importance of Leukemic Cell Heterogeneity, Neighbouring Mesenchymal Stem Cells and Immunocompetent Cells.
    Brenner AK, Andersson Tvedt TH, Bruserud Ø.
    Molecules; 2016 Nov 11; 21(11):. PubMed ID: 27845732
    [Abstract] [Full Text] [Related]

  • 7. Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia.
    Zeng Z, Samudio IJ, Zhang W, Estrov Z, Pelicano H, Harris D, Frolova O, Hail N, Chen W, Kornblau SM, Huang P, Lu Y, Mills GB, Andreeff M, Konopleva M.
    Cancer Res; 2006 Apr 01; 66(7):3737-46. PubMed ID: 16585200
    [Abstract] [Full Text] [Related]

  • 8. Arsenic disulfide synergizes with the phosphoinositide 3-kinase inhibitor PI-103 to eradicate acute myeloid leukemia stem cells by inducing differentiation.
    Hong Z, Xiao M, Yang Y, Han Z, Cao Y, Li C, Wu Y, Gong Q, Zhou X, Xu D, Meng L, Ma D, Zhou J.
    Carcinogenesis; 2011 Oct 01; 32(10):1550-8. PubMed ID: 21803735
    [Abstract] [Full Text] [Related]

  • 9. Propofol enhances BCR-ABL TKIs' inhibitory effects in chronic myeloid leukemia through Akt/mTOR suppression.
    Tan Z, Peng A, Xu J, Ouyang M.
    BMC Anesthesiol; 2017 Sep 29; 17(1):132. PubMed ID: 28962554
    [Abstract] [Full Text] [Related]

  • 10. Rhein exerts anti-multidrug resistance in acute myeloid leukemia via targeting FTO to inhibit AKT/mTOR.
    Zhang S, Zhou L, Yang J, Lu J, Tao L, Feng Y, Cheng J, Zhao L.
    Anticancer Drugs; 2024 Aug 01; 35(7):597-605. PubMed ID: 38728095
    [Abstract] [Full Text] [Related]

  • 11. The pan-class I phosphatidyl-inositol-3 kinase inhibitor NVP-BKM120 demonstrates anti-leukemic activity in acute myeloid leukemia.
    Allegretti M, Ricciardi MR, Licchetta R, Mirabilii S, Orecchioni S, Reggiani F, Talarico G, Foà R, Bertolini F, Amadori S, Torrisi MR, Tafuri A.
    Sci Rep; 2015 Dec 17; 5():18137. PubMed ID: 26674543
    [Abstract] [Full Text] [Related]

  • 12. Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in acute myeloid leukemia revealed by pathway selective inhibition and phosphoproteome analysis.
    Bertacchini J, Guida M, Accordi B, Mediani L, Martelli AM, Barozzi P, Petricoin E, Liotta L, Milani G, Giordan M, Luppi M, Forghieri F, De Pol A, Cocco L, Basso G, Marmiroli S.
    Leukemia; 2014 Nov 17; 28(11):2197-205. PubMed ID: 24699302
    [Abstract] [Full Text] [Related]

  • 13. Therapeutic effects of antibiotic drug mefloquine against cervical cancer through impairing mitochondrial function and inhibiting mTOR pathway.
    Li H, Jiao S, Li X, Banu H, Hamal S, Wang X.
    Can J Physiol Pharmacol; 2017 Jan 17; 95(1):43-50. PubMed ID: 27831748
    [Abstract] [Full Text] [Related]

  • 14. An α-acetoxy-tirucallic acid isomer inhibits Akt/mTOR signaling and induces oxidative stress in prostate cancer cells.
    El Gaafary M, Büchele B, Syrovets T, Agnolet S, Schneider B, Schmidt CQ, Simmet T.
    J Pharmacol Exp Ther; 2015 Jan 17; 352(1):33-42. PubMed ID: 25316122
    [Abstract] [Full Text] [Related]

  • 15. Propofol inhibits biological functions of leukaemia stem and differentiated cells through suppressing Wnt/β-catenin and Akt/mTOR.
    Chen L, Wan Y, Liu Y, Li T.
    Clin Exp Pharmacol Physiol; 2020 Jan 17; 47(1):127-134. PubMed ID: 31429973
    [Abstract] [Full Text] [Related]

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  • 17. CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway.
    Wen Q, Wang W, Luo J, Chu S, Chen L, Xu L, Zang H, Alnemah MM, Ma J, Fan S.
    Oncotarget; 2016 May 10; 7(19):27787-801. PubMed ID: 27050281
    [Abstract] [Full Text] [Related]

  • 18. MLN0128, a novel mTOR kinase inhibitor, disrupts survival signaling and triggers apoptosis in AML and AML stem/ progenitor cells.
    Zeng Z, Wang RY, Qiu YH, Mak DH, Coombes K, Yoo SY, Zhang Q, Jessen K, Liu Y, Rommel C, Fruman DA, Kantarjian HM, Kornblau SM, Andreeff M, Konopleva M.
    Oncotarget; 2016 Aug 23; 7(34):55083-55097. PubMed ID: 27391151
    [Abstract] [Full Text] [Related]

  • 19. PIM and AKT kinase inhibitors show synergistic cytotoxicity in acute myeloid leukaemia that is associated with convergence on mTOR and MCL1 pathways.
    Meja K, Stengel C, Sellar R, Huszar D, Davies BR, Gale RE, Linch DC, Khwaja A.
    Br J Haematol; 2014 Oct 23; 167(1):69-79. PubMed ID: 24975213
    [Abstract] [Full Text] [Related]

  • 20. Sinularin Induces Apoptosis through Mitochondria Dysfunction and Inactivation of the pI3K/Akt/mTOR Pathway in Gastric Carcinoma Cells.
    Wu YJ, Wong BS, Yea SH, Lu CI, Weng SH.
    Mar Drugs; 2016 Jul 27; 14(8):. PubMed ID: 27472346
    [Abstract] [Full Text] [Related]

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