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178 related items for PubMed ID: 2989498

  • 1. Disposition of enalapril in the perfused rat intestine-liver preparation: absorption, metabolism and first-pass effect.
    Pang KS, Cherry WF, Ulm EH.
    J Pharmacol Exp Ther; 1985 Jun; 233(3):788-95. PubMed ID: 2989498
    [Abstract] [Full Text] [Related]

  • 2. Disposition of enalapril and its diacid metabolite, enalaprilat, in a perfused rat liver preparation. Presence of a diffusional barrier for enalaprilat into hepatocytes.
    Pang KS, Cherry WF, Terrell JA, Ulm EH.
    Drug Metab Dispos; 1984 Jun; 12(3):309-13. PubMed ID: 6145558
    [Abstract] [Full Text] [Related]

  • 3. Esterases for enalapril hydrolysis are concentrated in the perihepatic venous region of the rat liver.
    Pang KS, Barker F, Cherry WF, Goresky CA.
    J Pharmacol Exp Ther; 1991 Apr; 257(1):294-301. PubMed ID: 1850468
    [Abstract] [Full Text] [Related]

  • 4. Absorption and metabolism of acetaminophen by the in situ perfused rat small intestine preparation.
    Pang KS, Yuen V, Fayz S, te Koppele JM, Mulder GJ.
    Drug Metab Dispos; 1986 Apr; 14(1):102-11. PubMed ID: 2868852
    [Abstract] [Full Text] [Related]

  • 5. First-pass metabolism of gentisamide: influence of intestinal metabolism on hepatic formation of conjugates. Studies in the once-through vascularly perfused rat intestine-liver preparation.
    Hirayama H, Pang KS.
    Drug Metab Dispos; 1990 Apr; 18(5):580-7. PubMed ID: 1981705
    [Abstract] [Full Text] [Related]

  • 6. First-pass metabolism of salicylamide. Studies in the once-through vascularly perfused rat intestine-liver preparation.
    Xu X, Hirayama H, Pang KS.
    Drug Metab Dispos; 1989 Apr; 17(5):556-63. PubMed ID: 2573500
    [Abstract] [Full Text] [Related]

  • 7. Role of the hepatic artery in the metabolism of phenacetin and acetaminophen: intravital microscopic and multiple-indicator dilution study in perfused rat liver.
    Pang KS, Sherman IA, Schwab AJ, Geng W, Barker F, Dlugosz JA, Cuerrier G, Goresky CA.
    Hepatology; 1994 Sep; 20(3):672-83. PubMed ID: 8076925
    [Abstract] [Full Text] [Related]

  • 8. Effect of flow on first-pass metabolism of drugs: single pass studies on 4-methylumbelliferone conjugation in the serially perfused rat intestine and liver preparations.
    Chen J, Pang KS.
    J Pharmacol Exp Ther; 1997 Jan; 280(1):24-31. PubMed ID: 8996177
    [Abstract] [Full Text] [Related]

  • 9. Renal handling of enalapril and enalaprilat: studies in the isolated red blood cell-perfused rat kidney.
    de Lannoy IA, Nespeca R, Pang KS.
    J Pharmacol Exp Ther; 1989 Dec; 251(3):1211-22. PubMed ID: 2557416
    [Abstract] [Full Text] [Related]

  • 10. Estimations of intestinal and liver first-pass metabolism in vivo. Studies on gentisamide conjugation in the rat.
    Hirayama H, Morgado J, Gasinska I, Pang KS.
    Drug Metab Dispos; 1990 Dec; 18(5):588-94. PubMed ID: 1981706
    [Abstract] [Full Text] [Related]

  • 11. Glycine conjugation activity of benzoic acid and its acinar localization in the perfused rat liver.
    Chiba M, Poon K, Hollands J, Pang KS.
    J Pharmacol Exp Ther; 1994 Jan; 268(1):409-16. PubMed ID: 8301581
    [Abstract] [Full Text] [Related]

  • 12. The physiological disposition and metabolism of enalapril maleate in laboratory animals.
    Tocco DJ, deLuna FA, Duncan AE, Vassil TC, Ulm EH.
    Drug Metab Dispos; 1982 Jan; 10(1):15-9. PubMed ID: 6124377
    [Abstract] [Full Text] [Related]

  • 13. Intracellular and not intraluminal esterolysis of enalapril in kidney. Studies with the single pass perfused nonfiltering rat kidney.
    Sirianni GL, Pang KS.
    Drug Metab Dispos; 1998 Apr; 26(4):324-31. PubMed ID: 9531519
    [Abstract] [Full Text] [Related]

  • 14. The Disposition of Oxymatrine in the Vascularly Perfused Rat Intestine-Liver Preparation and Its Metabolism in Rat Liver Microsomes.
    Huang LH, Zhong YM, Xiong XH, Cen MF, Cheng XG, Wang GX, Chen JS, Wang SJ.
    J Pharm Sci; 2016 Feb; 105(2):897-903. PubMed ID: 26869434
    [Abstract] [Full Text] [Related]

  • 15. Kinetics of metabolite formation and elimination in the perfused rat liver preparation: differences between the elimination of preformed acetaminophen and acetaminophen formed from phenacetin.
    Pang KS, Gillette JR.
    J Pharmacol Exp Ther; 1978 Oct; 207(1):178-94. PubMed ID: 702339
    [Abstract] [Full Text] [Related]

  • 16. Combined hepatic arterial-portal venous and hepatic arterial-hepatic venous perfusions to probe the abundance of drug metabolizing activities: perihepatic venous O-deethylation activity for phenacetin and periportal sulfation activity for acetaminophen in the once-through rat liver preparation.
    Pang KS, Cherry WF, Accaputo J, Schwab AJ, Goresky CA.
    J Pharmacol Exp Ther; 1988 Nov; 247(2):690-700. PubMed ID: 3183964
    [Abstract] [Full Text] [Related]

  • 17. Presence of a diffusional barrier on metabolite kinetics: enalaprilat as a generated versus preformed metabolite.
    de Lannoy IA, Pang KS.
    Drug Metab Dispos; 1986 Nov; 14(5):513-20. PubMed ID: 2876855
    [Abstract] [Full Text] [Related]

  • 18. Competing pathways in drug metabolism. I. Effect of input concentration on the conjugation of gentisamide in the once-through in situ perfused rat liver preparation.
    Morris ME, Yuen V, Tang BK, Pang KS.
    J Pharmacol Exp Ther; 1988 May; 245(2):614-24. PubMed ID: 3367309
    [Abstract] [Full Text] [Related]

  • 19. Dose-dependent kinetics of quinidine in the perfused rat liver preparation. Kinetics of formation of active metabolites.
    Yu VC, de Lamirande E, Horning MG, Pang KS.
    Drug Metab Dispos; 1982 May; 10(6):568-72. PubMed ID: 6130901
    [Abstract] [Full Text] [Related]

  • 20. Enalapril maleate (MK-421), a potent, nonsulfhydryl angiotensin-converting enzyme inhibitor: absorption, disposition, and metabolism in man.
    Ulm EH.
    Drug Metab Rev; 1983 May; 14(1):99-110. PubMed ID: 6301792
    [Abstract] [Full Text] [Related]

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