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207 related items for PubMed ID: 29912977

  • 1. Tongxinluo attenuates reperfusion injury in diabetic hearts by angiopoietin-like 4-mediated protection of endothelial barrier integrity via PPAR-α pathway.
    Qi K, Li X, Geng Y, Cui H, Jin C, Wang P, Li Y, Yang Y.
    PLoS One; 2018; 13(6):e0198403. PubMed ID: 29912977
    [Abstract] [Full Text] [Related]

  • 2. Tongxinluo attenuates oxygen-glucose-serum deprivation/restoration-induced endothelial barrier breakdown via peroxisome proliferator activated receptor-α/angiopoietin-like 4 pathway in high glucose-incubated human cardiac microvascular endothelial cells.
    Qi K, Yang Y, Geng Y, Cui H, Li X, Jin C, Chen G, Tian X, Meng X.
    Medicine (Baltimore); 2020 Aug 21; 99(34):e21821. PubMed ID: 32846824
    [Abstract] [Full Text] [Related]

  • 3. Preventive effect of Tongxinluo on endothelial survival and vascular integrity, together with inhibition of inflammatory reaction in rats model of intestine ischemia/reperfusion injury.
    Zhang JX, Li SD, Liu Y, Yang MH.
    Pak J Pharm Sci; 2018 Nov 21; 31(6):2403-2410. PubMed ID: 30473511
    [Abstract] [Full Text] [Related]

  • 4. Tongxinluo exerts protective effects via anti-apoptotic and pro-autophagic mechanisms by activating AMPK pathway in infarcted rat hearts.
    Li Q, Li N, Cui HH, Tian XQ, Jin C, Chen GH, Yang YJ.
    Exp Physiol; 2017 Apr 01; 102(4):422-435. PubMed ID: 28150462
    [Abstract] [Full Text] [Related]

  • 5. Quantitative Proteomics Analysis of Ischemia/Reperfusion Injury-Modulated Proteins in Cardiac Microvascular Endothelial Cells and the Protective Role of Tongxinluo.
    Li Q, Cui HH, Yang YJ, Li XD, Chen GH, Tian XQ, Jin C, Dong QT, Huang PS, Xu J.
    Cell Physiol Biochem; 2017 Apr 01; 41(4):1503-1518. PubMed ID: 28334711
    [Abstract] [Full Text] [Related]

  • 6. Induction of autophagy by Tongxinluo through the MEK/ERK pathway protects human cardiac microvascular endothelial cells from hypoxia/reoxygenation injury.
    Cui H, Li X, Li N, Qi K, Li Q, Jin C, Zhang Q, Jiang L, Yang Y.
    J Cardiovasc Pharmacol; 2014 Aug 01; 64(2):180-90. PubMed ID: 24705173
    [Abstract] [Full Text] [Related]

  • 7. Tongxinluo Attenuates Myocardiac Fibrosis after Acute Myocardial Infarction in Rats via Inhibition of Endothelial-to-Mesenchymal Transition.
    Yin Y, Zhang Q, Zhao Q, Ding G, Wei C, Chang L, Li H, Bei H, Wang H, Liang J, Jia Z.
    Biomed Res Int; 2019 Aug 01; 2019():6595437. PubMed ID: 31317035
    [Abstract] [Full Text] [Related]

  • 8. Protein kinase A-mediated cardioprotection of Tongxinluo relates to the inhibition of myocardial inflammation, apoptosis, and edema in reperfused swine hearts.
    Li XD, Yang YJ, Cheng YT, Dou KF, Tian Y, Meng XM.
    Chin Med J (Engl); 2013 Aug 01; 126(8):1469-79. PubMed ID: 23595379
    [Abstract] [Full Text] [Related]

  • 9. Cardiomyocyte-derived small extracellular vesicles can signal eNOS activation in cardiac microvascular endothelial cells to protect against Ischemia/Reperfusion injury.
    Chen G, Xu C, Gillette TG, Huang T, Huang P, Li Q, Li X, Li Q, Ning Y, Tang R, Huang C, Xiong Y, Tian X, Xu J, Xu J, Chang L, Wei C, Jin C, Hill JA, Yang Y.
    Theranostics; 2020 Aug 01; 10(25):11754-11774. PubMed ID: 33052245
    [Abstract] [Full Text] [Related]

  • 10. PI3K/Akt pathway contributes to neuroprotective effect of Tongxinluo against focal cerebral ischemia and reperfusion injury in rats.
    Yu ZH, Cai M, Xiang J, Zhang ZN, Zhang JS, Song XL, Zhang W, Bao J, Li WW, Cai DF.
    J Ethnopharmacol; 2016 Apr 02; 181():8-19. PubMed ID: 26805466
    [Abstract] [Full Text] [Related]

  • 11. Neuroprotective effects of Tongxinluo on focal cerebral ischemia and reperfusion injury in rats associated with the activation of the MEK1/2/ERK1/2/p90RSK signaling pathway.
    Yu Z, Cai M, Li X, Zhang J, Wu T, Yang F, Zhu W, Xiang Y, Zhang W, Xiang J, Cai D.
    Brain Res; 2018 Apr 15; 1685():9-18. PubMed ID: 29425910
    [Abstract] [Full Text] [Related]

  • 12. Tongxinluo reduces myocardial no-reflow and ischemia-reperfusion injury by stimulating the phosphorylation of eNOS via the PKA pathway.
    Li XD, Yang YJ, Geng YJ, Jin C, Hu FH, Zhao JL, Zhang HT, Cheng YT, Qian HY, Wang LL, Zhang BJ, Wu YL.
    Am J Physiol Heart Circ Physiol; 2010 Oct 15; 299(4):H1255-61. PubMed ID: 20693395
    [Abstract] [Full Text] [Related]

  • 13. Mast cell activation, TLR4-NF-κB/TNF-α pathway variation in rats' intestinal ischemia-reperfusion injury and Tongxinluo's therapeutic effect.
    Junxiu Z, Yu F, Yanyan H, Yin Z, Yi L, Minghui Y, Shaodan L.
    Pak J Pharm Sci; 2020 Jul 15; 33(4):1599-1608. PubMed ID: 33583793
    [Abstract] [Full Text] [Related]

  • 14. Cardiac microvascular barrier function mediates the protection of Tongxinluo against myocardial ischemia/reperfusion injury.
    Qi K, Li L, Li X, Zhao J, Wang Y, You S, Hu F, Zhang H, Cheng Y, Kang S, Cui H, Duan L, Jin C, Zheng Q, Yang Y.
    PLoS One; 2015 Jul 15; 10(3):e0119846. PubMed ID: 25781461
    [Abstract] [Full Text] [Related]

  • 15. Inhibition of miR-128-3p by Tongxinluo Protects Human Cardiomyocytes from Ischemia/reperfusion Injury via Upregulation of p70s6k1/p-p70s6k1.
    Chen GH, Xu CS, Zhang J, Li Q, Cui HH, Li XD, Chang LP, Tang RJ, Xu JY, Tian XQ, Huang PS, Xu J, Jin C, Yang YJ.
    Front Pharmacol; 2017 Jul 15; 8():775. PubMed ID: 29163161
    [Abstract] [Full Text] [Related]

  • 16. Tongxinluo Ameliorates Myocardial Ischemia-Reperfusion Injury Mainly via Activating Parkin-Mediated Mitophagy and Downregulating Ubiquitin-Proteasome System.
    Yang HX, Wang P, Wang NN, Li SD, Yang MH.
    Chin J Integr Med; 2021 Jul 15; 27(7):542-550. PubMed ID: 31227964
    [Abstract] [Full Text] [Related]

  • 17. Chinese medicine Tongxinluo increases tight junction protein levels by inducing KLF5 expression in microvascular endothelial cells.
    Li LM, Zheng B, Zhang RN, Jin LS, Zheng CY, Wang C, Zhou PP, Guo ZW, Ma D, Wen JK.
    Cell Biochem Funct; 2015 Jun 15; 33(4):226-34. PubMed ID: 25907265
    [Abstract] [Full Text] [Related]

  • 18. Tongxinluo Activates PI3K/AKT Signaling Pathway to Inhibit Endothelial Mesenchymal Transition and Attenuate Myocardial Fibrosis after Ischemia-Reperfusion in Mice.
    Wei YR, Hou YL, Yin YJ, Li Z, Liu Y, Han NX, Wang ZX, Liu L, Wang XQ, Hao YJ, Ma K, Gu JJ, Jia ZH.
    Chin J Integr Med; 2024 Jul 15; 30(7):608-615. PubMed ID: 38386252
    [Abstract] [Full Text] [Related]

  • 19. The sonic hedgehog pathway mediates Tongxinluo capsule-induced protection against blood-brain barrier disruption after ischaemic stroke in mice.
    Liu S, Chang L, Wei C.
    Basic Clin Pharmacol Toxicol; 2019 Jun 15; 124(6):660-669. PubMed ID: 30548093
    [Abstract] [Full Text] [Related]

  • 20. Tongxinluo (TXL), a Traditional Chinese Medicinal Compound, Improves Endothelial Function After Chronic Hypoxia Both In Vivo and In Vitro.
    Zheng CY, Song LL, Wen JK, Li LM, Guo ZW, Zhou PP, Wang C, Li YH, Ma D, Zheng B.
    J Cardiovasc Pharmacol; 2015 Jun 15; 65(6):579-86. PubMed ID: 26065642
    [Abstract] [Full Text] [Related]

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