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Journal Abstract Search

57 related items for PubMed ID: 29932909

  • 1. From Precise Slicing to General SHREDding: The Ubiquitin Ligase Ubr1 Roqs as a Multipurpose Protein Terminator.
    Gardner RG, Ravid T.
    Mol Cell; 2018 Jun 21; 70(6):989-990. PubMed ID: 29932909
    [Abstract] [Full Text] [Related]

  • 2. Degradation of misfolded protein in the cytoplasm is mediated by the ubiquitin ligase Ubr1.
    Eisele F, Wolf DH.
    FEBS Lett; 2008 Dec 24; 582(30):4143-6. PubMed ID: 19041308
    [Abstract] [Full Text] [Related]

  • 3. Pairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain.
    Du F, Navarro-Garcia F, Xia Z, Tasaki T, Varshavsky A.
    Proc Natl Acad Sci U S A; 2002 Oct 29; 99(22):14110-5. PubMed ID: 12391316
    [Abstract] [Full Text] [Related]

  • 4. SHRED Is a Regulatory Cascade that Reprograms Ubr1 Substrate Specificity for Enhanced Protein Quality Control during Stress.
    Szoradi T, Schaeff K, Garcia-Rivera EM, Itzhak DN, Schmidt RM, Bircham PW, Leiss K, Diaz-Miyar J, Chen VK, Muzzey D, Borner GHH, Schuck S.
    Mol Cell; 2018 Jun 21; 70(6):1025-1037.e5. PubMed ID: 29861160
    [Abstract] [Full Text] [Related]

  • 5. The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases.
    Hwang CS, Shemorry A, Auerbach D, Varshavsky A.
    Nat Cell Biol; 2010 Dec 21; 12(12):1177-85. PubMed ID: 21076411
    [Abstract] [Full Text] [Related]

  • 6. Regulation of peptide import through phosphorylation of Ubr1, the ubiquitin ligase of the N-end rule pathway.
    Hwang CS, Varshavsky A.
    Proc Natl Acad Sci U S A; 2008 Dec 09; 105(49):19188-93. PubMed ID: 19033468
    [Abstract] [Full Text] [Related]

  • 7. Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway.
    Kwon YT, Xia Z, Davydov IV, Lecker SH, Varshavsky A.
    Mol Cell Biol; 2001 Dec 09; 21(23):8007-21. PubMed ID: 11689692
    [Abstract] [Full Text] [Related]

  • 8. Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway.
    Xia Z, Webster A, Du F, Piatkov K, Ghislain M, Varshavsky A.
    J Biol Chem; 2008 Aug 29; 283(35):24011-28. PubMed ID: 18566452
    [Abstract] [Full Text] [Related]

  • 9. Molecular mass as a determinant for nuclear San1-dependent targeting of misfolded cytosolic proteins to proteasomal degradation.
    Amm I, Wolf DH.
    FEBS Lett; 2016 Jun 29; 590(12):1765-75. PubMed ID: 27173001
    [Abstract] [Full Text] [Related]

  • 10. The N-end rule pathway and Ubr1 enforce protein compartmentalization via P2-encoded cellular location signals.
    Tran A.
    J Cell Sci; 2019 May 07; 132(9):. PubMed ID: 30940687
    [Abstract] [Full Text] [Related]

  • 11. Cytoplasmic protein quality control degradation mediated by parallel actions of the E3 ubiquitin ligases Ubr1 and San1.
    Heck JW, Cheung SK, Hampton RY.
    Proc Natl Acad Sci U S A; 2010 Jan 19; 107(3):1106-11. PubMed ID: 20080635
    [Abstract] [Full Text] [Related]

  • 12. Peptides accelerate their uptake by activating a ubiquitin-dependent proteolytic pathway.
    Turner GC, Du F, Varshavsky A.
    Nature; 2000 Jun 01; 405(6786):579-83. PubMed ID: 10850718
    [Abstract] [Full Text] [Related]

  • 13. The mouse and human genes encoding the recognition component of the N-end rule pathway.
    Kwon YT, Reiss Y, Fried VA, Hershko A, Yoon JK, Gonda DK, Sangan P, Copeland NG, Jenkins NA, Varshavsky A.
    Proc Natl Acad Sci U S A; 1998 Jul 07; 95(14):7898-903. PubMed ID: 9653112
    [Abstract] [Full Text] [Related]

  • 14. In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.
    Gardner RG, Shearer AG, Hampton RY.
    Mol Cell Biol; 2001 Jul 07; 21(13):4276-91. PubMed ID: 11390656
    [Abstract] [Full Text] [Related]

  • 15. The yeast ubr1 ubiquitin ligase participates in a prominent pathway that targets cytosolic thermosensitive mutants for degradation.
    Khosrow-Khavar F, Fang NN, Ng AH, Winget JM, Comyn SA, Mayor T.
    G3 (Bethesda); 2012 May 07; 2(5):619-28. PubMed ID: 22670231
    [Abstract] [Full Text] [Related]

  • 16. Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndrome.
    Hwang CS, Sukalo M, Batygin O, Addor MC, Brunner H, Aytes AP, Mayerle J, Song HK, Varshavsky A, Zenker M.
    PLoS One; 2011 May 07; 6(9):e24925. PubMed ID: 21931868
    [Abstract] [Full Text] [Related]

  • 17. Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway.
    Kume K, Iizumi Y, Shimada M, Ito Y, Kishi T, Yamaguchi Y, Handa H.
    Genes Cells; 2010 Apr 01; 15(4):339-49. PubMed ID: 20298436
    [Abstract] [Full Text] [Related]

  • 18. The N-end rule pathway is a sensor of heme.
    Hu RG, Wang H, Xia Z, Varshavsky A.
    Proc Natl Acad Sci U S A; 2008 Jan 08; 105(1):76-81. PubMed ID: 18162538
    [Abstract] [Full Text] [Related]

  • 19. Proteolytic regulation of metabolic enzymes by E3 ubiquitin ligase complexes: lessons from yeast.
    Nakatsukasa K, Okumura F, Kamura T.
    Crit Rev Biochem Mol Biol; 2015 Jan 08; 50(6):489-502. PubMed ID: 26362128
    [Abstract] [Full Text] [Related]

  • 20. Analysis of higher plant N-degron pathway components and substrates via expression in S. cerevisiae.
    Böhm J, Winter N, Kozlic A, Telser T, Nehlin L, Bachmair A.
    Methods Enzymol; 2023 Jan 08; 686():221-233. PubMed ID: 37532401
    [Abstract] [Full Text] [Related]

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