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312 related items for PubMed ID: 29949391

  • 1. Increased megalin expression in early type 2 diabetes: role of insulin-signaling pathways.
    Bryniarski MA, Yee BM, Jaffri I, Chaves LD, Yu JA, Guan X, Ghavam N, Yacoub R, Morris ME.
    Am J Physiol Renal Physiol; 2018 Nov 01; 315(5):F1191-F1207. PubMed ID: 29949391
    [Abstract] [Full Text] [Related]

  • 2. Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin.
    Ren Q, Weyer K, Rbaibi Y, Long KR, Tan RJ, Nielsen R, Christensen EI, Baty CJ, Kashlan OB, Weisz OA.
    Am J Physiol Renal Physiol; 2020 May 01; 318(5):F1284-F1294. PubMed ID: 32200668
    [Abstract] [Full Text] [Related]

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  • 4. Diabetic rats present higher urinary loss of proteins and lower renal expression of megalin, cubilin, ClC-5, and CFTR.
    Figueira MF, Castiglione RC, de Lemos Barbosa CM, Ornellas FM, da Silva Feltran G, Morales MM, da Fonseca RN, de Souza-Menezes J.
    Physiol Rep; 2017 Jul 01; 5(13):. PubMed ID: 28676554
    [Abstract] [Full Text] [Related]

  • 5. Akt Links Insulin Signaling to Albumin Endocytosis in Proximal Tubule Epithelial Cells.
    Coffey S, Costacou T, Orchard T, Erkan E.
    PLoS One; 2015 Jul 01; 10(10):e0140417. PubMed ID: 26465605
    [Abstract] [Full Text] [Related]

  • 6. Regulation of megalin expression in cultured proximal tubule cells by angiotensin II type 1A receptor- and insulin-mediated signaling cross talk.
    Hosojima M, Sato H, Yamamoto K, Kaseda R, Soma T, Kobayashi A, Suzuki A, Kabasawa H, Takeyama A, Ikuyama K, Iino N, Nishiyama A, Thekkumkara TJ, Takeda T, Suzuki Y, Gejyo F, Saito A.
    Endocrinology; 2009 Feb 01; 150(2):871-8. PubMed ID: 18927221
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  • 7. Oxidative stress increases megalin expression in the renal proximal tubules during the normoalbuminuric stage of diabetes mellitus.
    Kurosaki Y, Imoto A, Kawakami F, Yokoba M, Takenaka T, Ichikawa T, Katagiri M, Ishii N.
    Am J Physiol Renal Physiol; 2018 Mar 01; 314(3):F462-F470. PubMed ID: 29187367
    [Abstract] [Full Text] [Related]

  • 8. Acute endotoxemia in mice induces downregulation of megalin and cubilin in the kidney.
    Schreiber A, Theilig F, Schweda F, Höcherl K.
    Kidney Int; 2012 Jul 01; 82(1):53-9. PubMed ID: 22437417
    [Abstract] [Full Text] [Related]

  • 9. High glucose reduces megalin-mediated albumin endocytosis in renal proximal tubule cells through protein kinase B O-GlcNAcylation.
    Peruchetti DB, Silva-Aguiar RP, Siqueira GM, Dias WB, Caruso-Neves C.
    J Biol Chem; 2018 Jul 20; 293(29):11388-11400. PubMed ID: 29871929
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  • 11. Transforming growth factor-beta1 reduces megalin- and cubilin-mediated endocytosis of albumin in proximal-tubule-derived opossum kidney cells.
    Gekle M, Knaus P, Nielsen R, Mildenberger S, Freudinger R, Wohlfarth V, Sauvant C, Christensen EI.
    J Physiol; 2003 Oct 15; 552(Pt 2):471-81. PubMed ID: 14561830
    [Abstract] [Full Text] [Related]

  • 12. Abolishment of proximal tubule albumin endocytosis does not affect plasma albumin during nephrotic syndrome in mice.
    Weyer K, Andersen PK, Schmidt K, Mollet G, Antignac C, Birn H, Nielsen R, Christensen EI.
    Kidney Int; 2018 Feb 15; 93(2):335-342. PubMed ID: 29032953
    [Abstract] [Full Text] [Related]

  • 13. NF-κB Inhibitor Parthenolide Promotes Renal Tubules Albumin Uptake in Type 2 Diabetic Nephropathy.
    Hao QF, Wang BB, Zhang W, Qiu W, Liu QL, Li XM.
    Chin Med Sci J; 2020 Mar 31; 35(1):31-42. PubMed ID: 32299536
    [Abstract] [Full Text] [Related]

  • 14. The proximal tubule and albuminuria: really!
    Dickson LE, Wagner MC, Sandoval RM, Molitoris BA.
    J Am Soc Nephrol; 2014 Mar 31; 25(3):443-53. PubMed ID: 24408874
    [Abstract] [Full Text] [Related]

  • 15. Cubilin is essential for albumin reabsorption in the renal proximal tubule.
    Amsellem S, Gburek J, Hamard G, Nielsen R, Willnow TE, Devuyst O, Nexo E, Verroust PJ, Christensen EI, Kozyraki R.
    J Am Soc Nephrol; 2010 Nov 31; 21(11):1859-67. PubMed ID: 20798259
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  • 16. Cubilin- and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney.
    Zhai XY, Nielsen R, Birn H, Drumm K, Mildenberger S, Freudinger R, Moestrup SK, Verroust PJ, Christensen EI, Gekle M.
    Kidney Int; 2000 Oct 31; 58(4):1523-33. PubMed ID: 11012887
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  • 17. Angiotensin II blockade restores albumin reabsorption in the proximal tubules of diabetic rats.
    Tojo A, Onozato ML, Kurihara H, Sakai T, Goto A, Fujita T.
    Hypertens Res; 2003 May 31; 26(5):413-9. PubMed ID: 12887133
    [Abstract] [Full Text] [Related]

  • 18. Lithium ameliorates tubule-interstitial injury through activation of the mTORC2/protein kinase B pathway.
    Teixeira DE, Peruchetti DB, Silva LS, Silva-Aguiar RP, Oquendo MB, Silva-Filho JL, Takiya CM, Leal-Cardoso JH, Pinheiro AAS, Caruso-Neves C.
    PLoS One; 2019 May 31; 14(4):e0215871. PubMed ID: 31002704
    [Abstract] [Full Text] [Related]

  • 19. Albumin Expands Albumin Reabsorption Capacity in Proximal Tubule Epithelial Cells through a Positive Feedback Loop between AKT and Megalin.
    Silva-Aguiar RP, Peruchetti DB, Florentino LS, Takiya CM, Marzolo MP, Dias WB, Pinheiro AAS, Caruso-Neves C.
    Int J Mol Sci; 2022 Jan 13; 23(2):. PubMed ID: 35055044
    [Abstract] [Full Text] [Related]

  • 20. Cubilin-, megalin-, and Dab2-dependent transcription revealed by CRISPR/Cas9 knockout in kidney proximal tubule cells.
    Long KR, Rbaibi Y, Bondi CD, Ford BR, Poholek AC, Boyd-Shiwarski CR, Tan RJ, Locker JD, Weisz OA.
    Am J Physiol Renal Physiol; 2022 Jan 01; 322(1):F14-F26. PubMed ID: 34747197
    [Abstract] [Full Text] [Related]

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