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Journal Abstract Search

471 related items for PubMed ID: 29953886

  • 1. (2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray.
    Chou D, Peng HY, Lin TB, Lai CY, Hsieh MC, Wen YC, Lee AS, Wang HH, Yang PS, Chen GD, Ho YC.
    Neuropharmacology; 2018 Sep 01; 139():1-12. PubMed ID: 29953886
    [Abstract] [Full Text] [Related]

  • 2. Ketamine metabolite (2R,6R)-hydroxynorketamine enhances aggression via periaqueductal gray glutamatergic transmission.
    Ye L, Ko CY, Huang Y, Zheng C, Zheng Y, Chou D.
    Neuropharmacology; 2019 Oct 01; 157():107667. PubMed ID: 31207251
    [Abstract] [Full Text] [Related]

  • 3. Brain-derived neurotrophic factor in the ventrolateral periaqueductal gray contributes to (2R,6R)-hydroxynorketamine-mediated actions.
    Chou D.
    Neuropharmacology; 2020 Jun 15; 170():108068. PubMed ID: 32222405
    [Abstract] [Full Text] [Related]

  • 4. Periaqueductal gray is required for controlling chronic stress-induced depression-like behavior.
    Peng WH, Kan HW, Ho YC.
    Biochem Biophys Res Commun; 2022 Feb 19; 593():28-34. PubMed ID: 35051779
    [Abstract] [Full Text] [Related]

  • 5. Periaqueductal Gray Glutamatergic Transmission Governs Chronic Stress-Induced Depression.
    Ho YC, Lin TB, Hsieh MC, Lai CY, Chou D, Chau YP, Chen GD, Peng HY.
    Neuropsychopharmacology; 2018 Jan 19; 43(2):302-312. PubMed ID: 28853438
    [Abstract] [Full Text] [Related]

  • 6. (2R,6R)-hydroxynorketamine rapidly potentiates hippocampal glutamatergic transmission through a synapse-specific presynaptic mechanism.
    Riggs LM, Aracava Y, Zanos P, Fischell J, Albuquerque EX, Pereira EFR, Thompson SM, Gould TD.
    Neuropsychopharmacology; 2020 Jan 19; 45(2):426-436. PubMed ID: 31216563
    [Abstract] [Full Text] [Related]

  • 7. NMDA receptor partial agonist GLYX-13 alleviates chronic stress-induced depression-like behavior through enhancement of AMPA receptor function in the periaqueductal gray.
    Yang PS, Peng HY, Lin TB, Hsieh MC, Lai CY, Lee AS, Wang HH, Ho YC.
    Neuropharmacology; 2020 Nov 01; 178():108269. PubMed ID: 32791085
    [Abstract] [Full Text] [Related]

  • 8. Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2R,6R)-hydroxynorketamine.
    Fukumoto K, Fogaça MV, Liu RJ, Duman C, Kato T, Li XY, Duman RS.
    Proc Natl Acad Sci U S A; 2019 Jan 02; 116(1):297-302. PubMed ID: 30559184
    [Abstract] [Full Text] [Related]

  • 9. Prelimbic cortex miR-34a contributes to (2R,6R)-hydroxynorketamine-mediated antidepressant-relevant actions.
    Ye L, Xiao X, Xu Y, Zheng C, Chen S, Luo T, Li Z, Du Y, Yuan Y, Li L, Liu B, Qin W, Chou D.
    Neuropharmacology; 2022 May 01; 208():108984. PubMed ID: 35131296
    [Abstract] [Full Text] [Related]

  • 10. Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function.
    Lumsden EW, Troppoli TA, Myers SJ, Zanos P, Aracava Y, Kehr J, Lovett J, Kim S, Wang FH, Schmidt S, Jenne CE, Yuan P, Morris PJ, Thomas CJ, Zarate CA, Moaddel R, Traynelis SF, Pereira EFR, Thompson SM, Albuquerque EX, Gould TD.
    Proc Natl Acad Sci U S A; 2019 Mar 12; 116(11):5160-5169. PubMed ID: 30796190
    [Abstract] [Full Text] [Related]

  • 11. BDNF-TrkB signaling-mediated upregulation of Narp is involved in the antidepressant-like effects of (2R,6R)-hydroxynorketamine in a chronic restraint stress mouse model.
    Ju L, Yang J, Zhu T, Liu P, Yang J.
    BMC Psychiatry; 2022 Mar 15; 22(1):182. PubMed ID: 35291971
    [Abstract] [Full Text] [Related]

  • 12. Pharmacological evaluation of clinically relevant concentrations of (2R,6R)-hydroxynorketamine.
    Shaffer CL, Dutra JK, Tseng WC, Weber ML, Bogart LJ, Hales K, Pang J, Volfson D, Am Ende CW, Green ME, Buhl DL.
    Neuropharmacology; 2019 Jul 15; 153():73-81. PubMed ID: 31015046
    [Abstract] [Full Text] [Related]

  • 13. (2R,6R)-hydroxynorketamine exerts mGlu2 receptor-dependent antidepressant actions.
    Zanos P, Highland JN, Stewart BW, Georgiou P, Jenne CE, Lovett J, Morris PJ, Thomas CJ, Moaddel R, Zarate CA, Gould TD.
    Proc Natl Acad Sci U S A; 2019 Mar 26; 116(13):6441-6450. PubMed ID: 30867285
    [Abstract] [Full Text] [Related]

  • 14. Sex-specific neurobiological actions of prophylactic (R,S)-ketamine, (2R,6R)-hydroxynorketamine, and (2S,6S)-hydroxynorketamine.
    Chen BK, Luna VM, LaGamma CT, Xu X, Deng SX, Suckow RF, Cooper TB, Shah A, Brachman RA, Mendez-David I, David DJ, Gardier AM, Landry DW, Denny CA.
    Neuropsychopharmacology; 2020 Aug 26; 45(9):1545-1556. PubMed ID: 32417852
    [Abstract] [Full Text] [Related]

  • 15. cAMP-dependent protein kinase signaling is required for (2R,6R)-hydroxynorketamine to potentiate hippocampal glutamatergic transmission.
    Riggs LM, Pereira EFR, Thompson SM, Gould TD.
    J Neurophysiol; 2024 Jan 01; 131(1):64-74. PubMed ID: 38050689
    [Abstract] [Full Text] [Related]

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  • 17. Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit.
    Yao N, Skiteva O, Zhang X, Svenningsson P, Chergui K.
    Mol Psychiatry; 2018 Oct 01; 23(10):2066-2077. PubMed ID: 29158578
    [Abstract] [Full Text] [Related]

  • 18. (2R,6R)-hydroxynorketamine rapidly potentiates optically-evoked Schaffer collateral synaptic activity.
    Riggs LM, Thompson SM, Gould TD.
    Neuropharmacology; 2022 Aug 15; 214():109153. PubMed ID: 35661657
    [Abstract] [Full Text] [Related]

  • 19. Topiramate inhibits offensive aggression through targeting ventrolateral periaqueductal gray.
    Chou D.
    Neuropharmacology; 2020 Dec 15; 181():108361. PubMed ID: 33096107
    [Abstract] [Full Text] [Related]

  • 20. Antidepressant actions of ketamine engage cell-specific translation via eIF4E.
    Aguilar-Valles A, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Khlaifia A, Skaleka A, Lopez-Canul M, Torres-Berrio A, Bermudez S, Rurak GM, Simard S, Salmaso N, Gobbi G, Lacaille JC, Sonenberg N.
    Nature; 2021 Feb 15; 590(7845):315-319. PubMed ID: 33328636
    [Abstract] [Full Text] [Related]

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