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2. CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions. Tiffner A, Schober R, Höglinger C, Bonhenry D, Pandey S, Lunz V, Sallinger M, Frischauf I, Fahrner M, Lindinger S, Maltan L, Berlansky S, Stadlbauer M, Schindl R, Ettrich R, Romanin C, Derler I. J Biol Chem; 2021; 296():100224. PubMed ID: 33361160 [Abstract] [Full Text] [Related]
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5. Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N terminus. Derler I, Butorac C, Krizova A, Stadlbauer M, Muik M, Fahrner M, Frischauf I, Romanin C. J Biol Chem; 2018 Jan 26; 293(4):1259-1270. PubMed ID: 29237734 [Abstract] [Full Text] [Related]
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7. The STIM1-binding site nexus remotely controls Orai1 channel gating. Zhou Y, Cai X, Loktionova NA, Wang X, Nwokonko RM, Wang X, Wang Y, Rothberg BS, Trebak M, Gill DL. Nat Commun; 2016 Dec 08; 7():13725. PubMed ID: 27929067 [Abstract] [Full Text] [Related]
9. The STIM-Orai coupling interface and gating of the Orai1 channel. Zhou Y, Cai X, Nwokonko RM, Loktionova NA, Wang Y, Gill DL. Cell Calcium; 2017 May 08; 63():8-13. PubMed ID: 28087079 [Abstract] [Full Text] [Related]
10. ORAI1 channel gating and selectivity is differentially altered by natural mutations in the first or third transmembrane domain. Bulla M, Gyimesi G, Kim JH, Bhardwaj R, Hediger MA, Frieden M, Demaurex N. J Physiol; 2019 Jan 08; 597(2):561-582. PubMed ID: 30382595 [Abstract] [Full Text] [Related]
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