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301 related items for PubMed ID: 29975542

  • 1. Importance of OCT2 and MATE1 for the Cimetidine-Metformin Interaction: Insights from Investigations of Polarized Transport in Single- And Double-Transfected MDCK Cells with a Focus on Perpetrator Disposition.
    Müller F, Weitz D, Mertsch K, König J, Fromm MF.
    Mol Pharm; 2018 Aug 06; 15(8):3425-3433. PubMed ID: 29975542
    [Abstract] [Full Text] [Related]

  • 2. Contribution of MATE1 to Renal Secretion of the NMDA Receptor Antagonist Memantine.
    Müller F, Weitz D, Derdau V, Sandvoss M, Mertsch K, König J, Fromm MF.
    Mol Pharm; 2017 Sep 05; 14(9):2991-2998. PubMed ID: 28708400
    [Abstract] [Full Text] [Related]

  • 3. Molecular mechanism of renal tubular secretion of the antimalarial drug chloroquine.
    Müller F, König J, Glaeser H, Schmidt I, Zolk O, Fromm MF, Maas R.
    Antimicrob Agents Chemother; 2011 Jul 05; 55(7):3091-8. PubMed ID: 21518836
    [Abstract] [Full Text] [Related]

  • 4. Renal tubular secretion of pramipexole.
    Knop J, Hoier E, Ebner T, Fromm MF, Müller F.
    Eur J Pharm Sci; 2015 Nov 15; 79():73-8. PubMed ID: 26360835
    [Abstract] [Full Text] [Related]

  • 5. Double-transfected MDCK cells expressing human OCT1/MATE1 or OCT2/MATE1: determinants of uptake and transcellular translocation of organic cations.
    König J, Zolk O, Singer K, Hoffmann C, Fromm MF.
    Br J Pharmacol; 2011 Jun 15; 163(3):546-55. PubMed ID: 20883471
    [Abstract] [Full Text] [Related]

  • 6. Interplay of the Organic Cation Transporters OCT1 and OCT2 with the Apically Localized Export Protein MATE1 for the Polarized Transport of Trospium.
    Deutsch B, Neumeister C, Schwantes U, Fromm MF, König J.
    Mol Pharm; 2019 Feb 04; 16(2):510-517. PubMed ID: 30656943
    [Abstract] [Full Text] [Related]

  • 7. Role of organic cation transporter OCT2 and multidrug and toxin extrusion proteins MATE1 and MATE2-K for transport and drug interactions of the antiviral lamivudine.
    Müller F, König J, Hoier E, Mandery K, Fromm MF.
    Biochem Pharmacol; 2013 Sep 15; 86(6):808-15. PubMed ID: 23876341
    [Abstract] [Full Text] [Related]

  • 8. Contribution of multidrug and toxin extrusion protein 1 (MATE1) to renal secretion of trimethylamine-N-oxide (TMAO).
    Gessner A, König J, Fromm MF.
    Sci Rep; 2018 Apr 27; 8(1):6659. PubMed ID: 29704007
    [Abstract] [Full Text] [Related]

  • 9. The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.
    Misaka S, Knop J, Singer K, Hoier E, Keiser M, Müller F, Glaeser H, König J, Fromm MF.
    Mol Pharm; 2016 Feb 01; 13(2):512-9. PubMed ID: 26702643
    [Abstract] [Full Text] [Related]

  • 10. Renal vectorial transport of berberine mediated by organic cation transporter 2 (OCT2) and multidrug and toxin extrusion proteins 1 (MATE1) in rats.
    Shi R, Yang Y, Xu Z, Dai Y, Zheng M, Wang T, Li Y, Ma Y.
    Biopharm Drug Dispos; 2018 Jan 01; 39(1):47-58. PubMed ID: 29065218
    [Abstract] [Full Text] [Related]

  • 11. In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs.
    George B, Wen X, Jaimes EA, Joy MS, Aleksunes LM.
    Int J Mol Sci; 2021 Jun 16; 22(12):. PubMed ID: 34208557
    [Abstract] [Full Text] [Related]

  • 12. Organic cation transporter and multidrug and toxin extrusion 1 co-mediated interaction between metformin and berberine.
    Shi R, Xu Z, Xu X, Jin J, Zhao Y, Wang T, Li Y, Ma Y.
    Eur J Pharm Sci; 2019 Jan 15; 127():282-290. PubMed ID: 30428337
    [Abstract] [Full Text] [Related]

  • 13. Emtricitabine is a substrate of MATE1 but not of OCT1, OCT2, P-gp, BCRP or MRP2 transporters.
    Reznicek J, Ceckova M, Cerveny L, Müller F, Staud F.
    Xenobiotica; 2017 Jan 15; 47(1):77-85. PubMed ID: 27052107
    [Abstract] [Full Text] [Related]

  • 14. Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K.
    Xiao G, Rowbottom C, Boiselle C, Gan LS.
    Pharm Res; 2018 Jun 18; 35(8):159. PubMed ID: 29915999
    [Abstract] [Full Text] [Related]

  • 15. [Establishment of MDCK cell models expressing human MATE1 or co-expressing with human OCT1 or OCT2].
    Lei HM, Sun SY, Li LP, Tu MJ, Zhou H, Zeng S, Jiang HD.
    Yao Xue Xue Bao; 2015 Jul 18; 50(7):842-7. PubMed ID: 26552145
    [Abstract] [Full Text] [Related]

  • 16. Impact of Substrate-Dependent Inhibition on Renal Organic Cation Transporters hOCT2 and hMATE1/2-K-Mediated Drug Transport and Intracellular Accumulation.
    Yin J, Duan H, Wang J.
    J Pharmacol Exp Ther; 2016 Dec 18; 359(3):401-410. PubMed ID: 27758931
    [Abstract] [Full Text] [Related]

  • 17. Role of OCT2 and MATE1 in renal disposition and toxicity of nitidine chloride.
    Li LP, Song FF, Weng YY, Yang X, Wang K, Lei HM, Ma J, Zhou H, Jiang HD.
    Br J Pharmacol; 2016 Aug 18; 173(16):2543-54. PubMed ID: 27324234
    [Abstract] [Full Text] [Related]

  • 18. Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.
    Ito S, Kusuhara H, Yokochi M, Toyoshima J, Inoue K, Yuasa H, Sugiyama Y.
    J Pharmacol Exp Ther; 2012 Feb 18; 340(2):393-403. PubMed ID: 22072731
    [Abstract] [Full Text] [Related]

  • 19. Efavirenz reduces renal excretion of lamivudine in rats by inhibiting organic cation transporters (OCT, Oct) and multidrug and toxin extrusion proteins (MATE, Mate).
    Ceckova M, Reznicek J, Deutsch B, Fromm MF, Staud F.
    PLoS One; 2018 Feb 18; 13(8):e0202706. PubMed ID: 30114293
    [Abstract] [Full Text] [Related]

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