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Journal Abstract Search


422 related items for PubMed ID: 29986184

  • 1. 3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
    Romagnoli R, Prencipe F, Oliva P, Baraldi S, Baraldi PG, Brancale A, Ferla S, Hamel E, Bortolozzi R, Viola G.
    Bioorg Chem; 2018 Oct; 80():361-374. PubMed ID: 29986184
    [Abstract] [Full Text] [Related]

  • 2. 2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition.
    Romagnoli R, Kimatrai Salvador M, Schiaffino Ortega S, Baraldi PG, Oliva P, Baraldi S, Lopez-Cara LC, Brancale A, Ferla S, Hamel E, Balzarini J, Liekens S, Mattiuzzo E, Basso G, Viola G.
    Eur J Med Chem; 2018 Jan 01; 143():683-698. PubMed ID: 29220790
    [Abstract] [Full Text] [Related]

  • 3. Design and synthesis of substituted dihydropyrimidinone derivatives as cytotoxic and tubulin polymerization inhibitors.
    Sana S, Tokala R, Bajaj DM, Nagesh N, Bokara KK, Kiranmai G, Lakshmi UJ, Vadlamani S, Talla V, Shankaraiah N.
    Bioorg Chem; 2019 Dec 01; 93():103317. PubMed ID: 31586714
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of 1-benzyl-N-(2-(phenylamino)pyridin-3-yl)-1H-1,2,3-triazole-4-carboxamides as antimitotic agents.
    Prasad B, Lakshma Nayak V, Srikanth PS, Baig MF, Subba Reddy NV, Babu KS, Kamal A.
    Bioorg Chem; 2019 Mar 01; 83():535-548. PubMed ID: 30472555
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of flexible and rigid analogs of 4H-1,2,4-triazoles bearing 3,4,5-trimethoxyphenyl moiety as new antiproliferative agents.
    Ansari M, Shokrzadeh M, Karima S, Rajaei S, Hashemi SM, Mirzaei H, Fallah M, Emami S.
    Bioorg Chem; 2019 Dec 01; 93():103300. PubMed ID: 31586708
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.
    Wang G, Peng F, Cao D, Yang Z, Han X, Liu J, Wu W, He L, Ma L, Chen J, Sang Y, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2013 Nov 01; 21(21):6844-54. PubMed ID: 23993668
    [Abstract] [Full Text] [Related]

  • 7. Design and synthesis of imidazo[2,1-b]thiazole-chalcone conjugates: microtubule-destabilizing agents.
    Kamal A, Balakrishna M, Nayak VL, Shaik TB, Faazil S, Nimbarte VD.
    ChemMedChem; 2014 Dec 01; 9(12):2766-80. PubMed ID: 25313981
    [Abstract] [Full Text] [Related]

  • 8. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 Dec 01; 21(8):1047-1055. PubMed ID: 32981511
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and bio-evaluation of novel 2-aryl-4-(3,4,5-trimethoxy-benzoyl)-5-substituted-1,2,3-triazoles as the tubulin polymerization inhibitors.
    Huang L, Liu M, Man S, Ma D, Feng D, Sun Z, Guan Q, Zuo D, Wu Y, Zhang W, Bao K.
    Eur J Med Chem; 2020 Jan 15; 186():111846. PubMed ID: 31740055
    [Abstract] [Full Text] [Related]

  • 10. Design and synthesis of aminostilbene-arylpropenones as tubulin polymerization inhibitors.
    Kamal A, Kumar GB, Polepalli S, Shaik AB, Reddy VS, Reddy MK, Reddy ChR, Mahesh R, Kapure JS, Jain N.
    ChemMedChem; 2014 Nov 15; 9(11):2565-79. PubMed ID: 25146959
    [Abstract] [Full Text] [Related]

  • 11. Design, synthesis and anticancer properties of IsoCombretaQuinolines as potent tubulin assembly inhibitors.
    Khelifi I, Naret T, Renko D, Hamze A, Bernadat G, Bignon J, Lenoir C, Dubois J, Brion JD, Provot O, Alami M.
    Eur J Med Chem; 2017 Feb 15; 127():1025-1034. PubMed ID: 28166995
    [Abstract] [Full Text] [Related]

  • 12. Synthesis of different heterocycles-linked chalcone conjugates as cytotoxic agents and tubulin polymerization inhibitors.
    Shankaraiah N, Nekkanti S, Brahma UR, Praveen Kumar N, Deshpande N, Prasanna D, Senwar KR, Jaya Lakshmi U.
    Bioorg Med Chem; 2017 Sep 01; 25(17):4805-4816. PubMed ID: 28774575
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and biological evaluation of indole-based [1,2,4]triazolo[4,3-a] pyridine derivatives as novel microtubule polymerization inhibitors.
    Wu CJ, Wu JQ, Hu Y, Pu S, Lin Y, Zeng Z, Hu J, Chen WH.
    Eur J Med Chem; 2021 Nov 05; 223():113629. PubMed ID: 34175541
    [Abstract] [Full Text] [Related]

  • 14. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
    Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R.
    J Med Chem; 2006 Jun 29; 49(13):3906-15. PubMed ID: 16789746
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and evaluation of antiproliferative and antitubulin activities of 5-methyl-4-aryl-3-(4-arylpiperazine-1-carbonyl)-4H-1,2,4-triazoles.
    Wang C, Li Y, Liu T, Wang Z, Zhang Y, Bao K, Wu Y, Guan Q, Zuo D, Zhang W.
    Bioorg Chem; 2020 Nov 29; 104():103909. PubMed ID: 33142419
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, biological evaluation, and structure-activity relationships of new tubulin polymerization inhibitors based on 5-amino-1,2,4-triazole scaffold.
    Yang F, Chen L, Lai JM, Jian XE, Lv DX, Yuan LL, Liu YX, Liang FT, Zheng XL, Li XL, Wei LY, You WW, Zhao PL.
    Bioorg Med Chem Lett; 2021 Apr 15; 38():127880. PubMed ID: 33636303
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors.
    Oliva P, Romagnoli R, Manfredini S, Brancale A, Ferla S, Hamel E, Ronca R, Maccarinelli F, Giacomini A, Rruga F, Mariotto E, Viola G, Bortolozzi R.
    Eur J Med Chem; 2020 Aug 15; 200():112448. PubMed ID: 32417696
    [Abstract] [Full Text] [Related]

  • 18. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
    Eissa IH, Dahab MA, Ibrahim MK, Alsaif NA, Alanazi AZ, Eissa SI, Mehany ABM, Beauchemin AM.
    Bioorg Chem; 2021 Jul 15; 112():104965. PubMed ID: 34020238
    [Abstract] [Full Text] [Related]

  • 19. β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells.
    Malebari AM, Fayne D, Nathwani SM, O'Connell F, Noorani S, Twamley B, O'Boyle NM, O'Sullivan J, Zisterer DM, Meegan MJ.
    Eur J Med Chem; 2020 Mar 01; 189():112050. PubMed ID: 31954879
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of imidazo[2,1-b][1,3,4]thiadiazole-linked oxindoles as potent tubulin polymerization inhibitors.
    Kamal A, Rao MP, Das P, Swapna P, Polepalli S, Nimbarte VD, Mullagiri K, Kovvuri J, Jain N.
    ChemMedChem; 2014 Jul 01; 9(7):1463-75. PubMed ID: 24715721
    [Abstract] [Full Text] [Related]


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