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641 related items for PubMed ID: 29989652

  • 1. Oxymatrine induces cell cycle arrest and apoptosis and suppresses the invasion of human glioblastoma cells through the EGFR/PI3K/Akt/mTOR signaling pathway and STAT3.
    Dai Z, Wang L, Wang X, Zhao B, Zhao W, Bhardwaj SS, Ye J, Yin Z, Zhang J, Zhao S.
    Oncol Rep; 2018 Aug; 40(2):867-876. PubMed ID: 29989652
    [Abstract] [Full Text] [Related]

  • 2. Oxymatrine targets EGFR(p-Tyr845) and inhibits EGFR-related signaling pathways to suppress the proliferation and invasion of gastric cancer cells.
    Guo B, Zhang T, Su J, Wang K, Li X.
    Cancer Chemother Pharmacol; 2015 Feb; 75(2):353-63. PubMed ID: 25527205
    [Abstract] [Full Text] [Related]

  • 3. Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway.
    ShuoWang, Song Z, Gong X, Ou C, Zhang W, Wang J, Yao C, Qin S, Yan B, Li Q, Wei K, Hou X, Zhou X, Miao J.
    J Ethnopharmacol; 2021 May 10; 271():113879. PubMed ID: 33524509
    [Abstract] [Full Text] [Related]

  • 4. Fucoxanthin Activates Apoptosis via Inhibition of PI3K/Akt/mTOR Pathway and Suppresses Invasion and Migration by Restriction of p38-MMP-2/9 Pathway in Human Glioblastoma Cells.
    Liu Y, Zheng J, Zhang Y, Wang Z, Yang Y, Bai M, Dai Y.
    Neurochem Res; 2016 Oct 10; 41(10):2728-2751. PubMed ID: 27394418
    [Abstract] [Full Text] [Related]

  • 5. Oxymatrine synergistically enhances antitumor activity of oxaliplatin in colon carcinoma through PI3K/AKT/mTOR pathway.
    Liu Y, Bi T, Wang Z, Wu G, Qian L, Gao Q, Shen G.
    Apoptosis; 2016 Dec 10; 21(12):1398-1407. PubMed ID: 27671687
    [Abstract] [Full Text] [Related]

  • 6. 2-(2-(2,4-dioxopentan-3-ylidene)hydrazineyl)benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma.
    Viswanathan A, Kute D, Musa A, Konda Mani S, Sipilä V, Emmert-Streib F, Zubkov FI, Gurbanov AV, Yli-Harja O, Kandhavelu M.
    Eur J Med Chem; 2019 Mar 15; 166():291-303. PubMed ID: 30731398
    [Abstract] [Full Text] [Related]

  • 7. Anticancer effects of veratramine via the phosphatidylinositol-3-kinase/serine-threonine kinase/mechanistic target of rapamycin and its downstream signaling pathways in human glioblastoma cell lines.
    Kim D, Kwon W, Park S, Kim W, Park JK, Han JE, Cho GJ, Yun S, Han SH, Kim MO, Ryoo ZY, Choi SK.
    Life Sci; 2022 Jan 01; 288():120170. PubMed ID: 34826438
    [Abstract] [Full Text] [Related]

  • 8. A novel matrine derivate inhibits differentiated human hepatoma cells and hepatic cancer stem-like cells by suppressing PI3K/AKT signaling pathways.
    Liu Y, Qi Y, Bai ZH, Ni CX, Ren QH, Xu WH, Xu J, Hu HG, Qiu L, Li JZ, He ZG, Zhang JP.
    Acta Pharmacol Sin; 2017 Jan 01; 38(1):120-132. PubMed ID: 27773936
    [Abstract] [Full Text] [Related]

  • 9. Ganoderic acid A holds promising cytotoxicity on human glioblastoma mediated by incurring apoptosis and autophagy and inactivating PI3K/AKT signaling pathway.
    Cheng Y, Xie P.
    J Biochem Mol Toxicol; 2019 Nov 01; 33(11):e22392. PubMed ID: 31503386
    [Abstract] [Full Text] [Related]

  • 10. NVP-BEZ235, a novel dual PI3K-mTOR inhibitor displays anti-glioma activity and reduces chemoresistance to temozolomide in human glioma cells.
    Yu Z, Xie G, Zhou G, Cheng Y, Zhang G, Yao G, Chen Y, Li Y, Zhao G.
    Cancer Lett; 2015 Oct 10; 367(1):58-68. PubMed ID: 26188279
    [Abstract] [Full Text] [Related]

  • 11. Matrine exerts anti‑breast cancer activity by mediating apoptosis and protective autophagy via the AKT/mTOR pathway in MCF‑7 cells.
    Du J, Li J, Song D, Li Q, Li L, Li B, Li L.
    Mol Med Rep; 2020 Nov 10; 22(5):3659-3666. PubMed ID: 33000249
    [Abstract] [Full Text] [Related]

  • 12. Phloretin induces cell cycle arrest and apoptosis of human glioblastoma cells through the generation of reactive oxygen species.
    Liu Y, Fan C, Pu L, Wei C, Jin H, Teng Y, Zhao M, Yu AC, Jiang F, Shu J, Li F, Peng Q, Kong J, Pan B, Zheng L, Huang Y.
    J Neurooncol; 2016 Jun 10; 128(2):217-23. PubMed ID: 26983952
    [Abstract] [Full Text] [Related]

  • 13. Oxymatrine inhibits non-small cell lung cancer via suppression of EGFR signaling pathway.
    Li W, Yu X, Tan S, Liu W, Zhou L, Liu H.
    Cancer Med; 2018 Jan 10; 7(1):208-218. PubMed ID: 29239135
    [Abstract] [Full Text] [Related]

  • 14. Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway.
    Zhou W, Wang J, Qi Q, Feng Z, Huang B, Chen A, Zhang D, Li W, Zhang Q, Bjerkvig R, Li X, Wang J.
    Cancer Med; 2018 Sep 10; 7(9):4729-4743. PubMed ID: 30079478
    [Abstract] [Full Text] [Related]

  • 15. Isoliquiritigenin inhibits proliferation and metastasis of MKN28 gastric cancer cells by suppressing the PI3K/AKT/mTOR signaling pathway.
    Zhang XR, Wang SY, Sun W, Wei C.
    Mol Med Rep; 2018 Sep 10; 18(3):3429-3436. PubMed ID: 30066879
    [Abstract] [Full Text] [Related]

  • 16. Cucurmosin induces apoptosis of BxPC-3 human pancreatic cancer cells via inactivation of the EGFR signaling pathway.
    Zhang B, Huang H, Xie J, Xu C, Chen M, Wang C, Yang A, Yin Q.
    Oncol Rep; 2012 Mar 10; 27(3):891-7. PubMed ID: 22139427
    [Abstract] [Full Text] [Related]

  • 17. Matrine inhibits invasion and migration of gallbladder cancer via regulating the PI3K/AKT signaling pathway.
    Mo RL, Li Z, Zhang P, Sheng MH, Han GC, Sun DQ.
    Naunyn Schmiedebergs Arch Pharmacol; 2024 Oct 10; 397(10):8129-8143. PubMed ID: 38789637
    [Abstract] [Full Text] [Related]

  • 18. Mahanimbine Exerts Anticancer Effects on Human Pancreatic Cancer Cells by Triggering Cell Cycle Arrest, Apoptosis, and Modulation of AKT/Mammalian Target of Rapamycin (mTOR) and Signal Transducer and Activator of Transcription 3 (STAT3) Signalling Pathways.
    Pei C, He Q, Liang S, Gong X.
    Med Sci Monit; 2018 Oct 01; 24():6975-6983. PubMed ID: 30273298
    [Abstract] [Full Text] [Related]

  • 19. Oxymatrine induces mitochondria dependent apoptosis in human osteosarcoma MNNG/HOS cells through inhibition of PI3K/Akt pathway.
    Zhang Y, Sun S, Chen J, Ren P, Hu Y, Cao Z, Sun H, Ding Y.
    Tumour Biol; 2014 Feb 01; 35(2):1619-25. PubMed ID: 24078465
    [Abstract] [Full Text] [Related]

  • 20. Latcripin-7A from Lentinula edodes C91-3 induces apoptosis, autophagy, and cell cycle arrest at G1 phase in human gastric cancer cells via inhibiting PI3K/Akt/mTOR signaling.
    Din SRU, Nisar MA, Ramzan MN, Saleem MZ, Ghayas H, Ahmad B, Batool S, Kifayat K, Guo X, Huang M, Zhong M.
    Eur J Pharmacol; 2021 Sep 15; 907():174305. PubMed ID: 34224698
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