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Journal Abstract Search
245 related items for PubMed ID: 30018138
1. Plasminogen activation triggers transthyretin amyloidogenesis in vitro. Mangione PP, Verona G, Corazza A, Marcoux J, Canetti D, Giorgetti S, Raimondi S, Stoppini M, Esposito M, Relini A, Canale C, Valli M, Marchese L, Faravelli G, Obici L, Hawkins PN, Taylor GW, Gillmore JD, Pepys MB, Bellotti V. J Biol Chem; 2018 Sep 14; 293(37):14192-14199. PubMed ID: 30018138 [Abstract] [Full Text] [Related]
2. Plasmin activity promotes amyloid deposition in a transgenic model of human transthyretin amyloidosis. Slamova I, Adib R, Ellmerich S, Golos MR, Gilbertson JA, Botcher N, Canetti D, Taylor GW, Rendell N, Tennent GA, Verona G, Porcari R, Mangione PP, Gillmore JD, Pepys MB, Bellotti V, Hawkins PN, Al-Shawi R, Simons JP. Nat Commun; 2021 Dec 07; 12(1):7112. PubMed ID: 34876572 [Abstract] [Full Text] [Related]
3. A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH. Ueda M, Okada M, Mizuguchi M, Kluve-Beckerman B, Kanenawa K, Isoguchi A, Misumi Y, Tasaki M, Ueda A, Kanai A, Sasaki R, Masuda T, Inoue Y, Nomura T, Shinriki S, Shuto T, Kai H, Yamashita T, Matsui H, Benson MD, Ando Y. J Biol Chem; 2019 Jul 19; 294(29):11259-11275. PubMed ID: 31167790 [Abstract] [Full Text] [Related]
4. Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Mangione PP, Porcari R, Gillmore JD, Pucci P, Monti M, Porcari M, Giorgetti S, Marchese L, Raimondi S, Serpell LC, Chen W, Relini A, Marcoux J, Clatworthy IR, Taylor GW, Tennent GA, Robinson CV, Hawkins PN, Stoppini M, Wood SP, Pepys MB, Bellotti V. Proc Natl Acad Sci U S A; 2014 Jan 28; 111(4):1539-44. PubMed ID: 24474780 [Abstract] [Full Text] [Related]
5. In Vitro and In Vivo Effects of SerpinA1 on the Modulation of Transthyretin Proteolysis. Bezerra F, Niemietz C, Schmidt HHJ, Zibert A, Guo S, Monia BP, Gonçalves P, Saraiva MJ, Almeida MR. Int J Mol Sci; 2021 Aug 31; 22(17):. PubMed ID: 34502397 [Abstract] [Full Text] [Related]
7. Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities. Foguel D, Suarez MC, Ferrão-Gonzales AD, Porto TC, Palmieri L, Einsiedler CM, Andrade LR, Lashuel HA, Lansbury PT, Kelly JW, Silva JL. Proc Natl Acad Sci U S A; 2003 Aug 19; 100(17):9831-6. PubMed ID: 12900507 [Abstract] [Full Text] [Related]
9. Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel. Verona G, Mangione PP, Raimondi S, Giorgetti S, Faravelli G, Porcari R, Corazza A, Gillmore JD, Hawkins PN, Pepys MB, Taylor GW, Bellotti V. Sci Rep; 2017 Mar 15; 7(1):182. PubMed ID: 28298647 [Abstract] [Full Text] [Related]
10. Specific disruption of transthyretin(105-115) fibrilization using "stabilizing" inhibitors of transthyretin amyloidogenesis. Liang Y, Ore MO, Morin S, Wilson DJ. Biochemistry; 2012 Apr 24; 51(16):3523-30. PubMed ID: 22482799 [Abstract] [Full Text] [Related]
11. Transthyretin forms amyloid fibrils at physiological pH with ultrasonication. Misumi Y, Ueda M, Fujimori H, Shinriki S, Meng W, Kim J, Saito S, Obayashi K, Uchino M, Ando Y. Amyloid; 2008 Dec 24; 15(4):234-9. PubMed ID: 19065294 [Abstract] [Full Text] [Related]
12. Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses. Almeida MR, Gales L, Damas AM, Cardoso I, Saraiva MJ. Curr Drug Targets CNS Neurol Disord; 2005 Oct 24; 4(5):587-96. PubMed ID: 16266291 [Abstract] [Full Text] [Related]
13. Mechanisms of transthyretin amyloidogenesis. Antigenic mapping of transthyretin purified from plasma and amyloid fibrils and within in situ tissue localizations. Gustavsson A, Engström U, Westermark P. Am J Pathol; 1994 Jun 24; 144(6):1301-11. PubMed ID: 8203468 [Abstract] [Full Text] [Related]
14. Transthyretin Anti-Amyloidogenic and Fibril Disrupting Activities of Bacopa monnieri (L.) Wettst (Brahmi) Extract. Eze FN, Ingkaninan K, Prapunpoj P. Biomolecules; 2019 Dec 09; 9(12):. PubMed ID: 31835306 [Abstract] [Full Text] [Related]
17. The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid. Lai Z, Colón W, Kelly JW. Biochemistry; 1996 May 21; 35(20):6470-82. PubMed ID: 8639594 [Abstract] [Full Text] [Related]
18. Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition. Saelices L, Chung K, Lee JH, Cohn W, Whitelegge JP, Benson MD, Eisenberg DS. Proc Natl Acad Sci U S A; 2018 Jul 17; 115(29):E6741-E6750. PubMed ID: 29954863 [Abstract] [Full Text] [Related]