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Journal Abstract Search

372 related items for PubMed ID: 3002440

  • 1. Effects of the DNA intercalators 4'-(9-acridinylamino)methanesulfon-m-anisidide and 2-methyl-9-hydroxyellipticinium on topoisomerase II mediated DNA strand cleavage and strand passage.
    Pommier Y, Minford JK, Schwartz RE, Zwelling LA, Kohn KW.
    Biochemistry; 1985 Nov 05; 24(23):6410-6. PubMed ID: 3002440
    [Abstract] [Full Text] [Related]

  • 2. Effects of DNA intercalating agents on topoisomerase II induced DNA strand cleavage in isolated mammalian cell nuclei.
    Pommier Y, Schwartz RE, Zwelling LA, Kohn KW.
    Biochemistry; 1985 Nov 05; 24(23):6406-10. PubMed ID: 3002439
    [Abstract] [Full Text] [Related]

  • 3. Protein-associated deoxyribonucleic acid strand breaks in L1210 cells treated with the deoxyribonucleic acid intercalating agents 4'-(9-acridinylamino) methanesulfon-m-anisidide and adriamycin.
    Zwelling LA, Michaels S, Erickson LC, Ungerleider RS, Nichols M, Kohn KW.
    Biochemistry; 1981 Nov 10; 20(23):6553-63. PubMed ID: 6895473
    [Abstract] [Full Text] [Related]

  • 4. Formation and rejoining of deoxyribonucleic acid double-strand breaks induced in isolated cell nuclei by antineoplastic intercalating agents.
    Pommier Y, Schwartz RE, Kohn KW, Zwelling LA.
    Biochemistry; 1984 Jul 03; 23(14):3194-201. PubMed ID: 6087890
    [Abstract] [Full Text] [Related]

  • 5. Effect of difluoromethylornithine, an inhibitor of polyamine biosynthesis, on the topoisomerase II-mediated DNA scission produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide in L1210 murine leukemia cells.
    Zwelling LA, Kerrigan D, Marton LJ.
    Cancer Res; 1985 Mar 03; 45(3):1122-6. PubMed ID: 2982483
    [Abstract] [Full Text] [Related]

  • 6. Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.
    Tewey KM, Chen GL, Nelson EM, Liu LF.
    J Biol Chem; 1984 Jul 25; 259(14):9182-7. PubMed ID: 6086625
    [Abstract] [Full Text] [Related]

  • 7. Topoisomerase II-mediated DNA damage produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: relation to cytotoxicity.
    Covey JM, Kohn KW, Kerrigan D, Tilchen EJ, Pommier Y.
    Cancer Res; 1988 Feb 15; 48(4):860-5. PubMed ID: 2827887
    [Abstract] [Full Text] [Related]

  • 8. Isolation of intercalator-dependent protein-linked DNA strand cleavage activity from cell nuclei and identification as topoisomerase II.
    Minford J, Pommier Y, Filipski J, Kohn KW, Kerrigan D, Mattern M, Michaels S, Schwartz R, Zwelling LA.
    Biochemistry; 1986 Jan 14; 25(1):9-16. PubMed ID: 3006754
    [Abstract] [Full Text] [Related]

  • 9. Changes in deoxyribonucleic acid linking number due to treatment of mammalian cells with the intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide.
    Pommier Y, Mattern MR, Schwartz RE, Zwelling LA, Kohn KW.
    Biochemistry; 1984 Jun 19; 23(13):2927-32. PubMed ID: 6547849
    [Abstract] [Full Text] [Related]

  • 10. Absence of a requirement for long-range DNA torsional strain in the production of protein-associated DNA strand breaks in isolated mammalian cell nuclei by the DNA intercalating agent 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA).
    Pommier Y, Zwelling LA, Schwartz RE, Mattern MR, Kohn KW.
    Biochem Pharmacol; 1984 Dec 01; 33(23):3909-12. PubMed ID: 6548917
    [No Abstract] [Full Text] [Related]

  • 11. Role of DNA intercalation in the inhibition of purified mouse leukemia (L1210) DNA topoisomerase II by 9-aminoacridines.
    Pommier Y, Covey J, Kerrigan D, Mattes W, Markovits J, Kohn KW.
    Biochem Pharmacol; 1987 Oct 15; 36(20):3477-86. PubMed ID: 2823823
    [Abstract] [Full Text] [Related]

  • 12. Production of protein-associated DNA breaks by 10-[diethylaminopropylamino]-6-methyl-5H-pyrido[3',4':4,5]pyrrolo [2,3-g]isoquinoline in cultured L1210 cells and in isolated nuclei: comparison with other topoisomerase II inhibitors.
    Pierson V, Pierre A, Pommier Y, Gros P.
    Cancer Res; 1988 Mar 15; 48(6):1404-9. PubMed ID: 2830964
    [Abstract] [Full Text] [Related]

  • 13. The production of topoisomerase II-mediated DNA cleavage in human leukemia cells predicts their susceptibility to 4'-(9-acridinylamino)methanesulfon-m-anisidide (m-AMSA).
    Bakic M, Beran M, Andersson BS, Silberman L, Estey E, Zwelling LA.
    Biochem Biophys Res Commun; 1986 Jan 29; 134(2):638-45. PubMed ID: 3004458
    [Abstract] [Full Text] [Related]

  • 14. Cross-resistance of an amsacrine-resistant human leukemia line to topoisomerase II reactive DNA intercalating agents. Evidence for two topoisomerase II directed drug actions.
    Zwelling LA, Mayes J, Hinds M, Chan D, Altschuler E, Carroll B, Parker E, Deisseroth K, Radcliffe A, Seligman M.
    Biochemistry; 1991 Apr 23; 30(16):4048-55. PubMed ID: 1850298
    [Abstract] [Full Text] [Related]

  • 15. Absence of swiveling at sites of intercalator-induced protein-associated deoxyribonucleic acid strand breaks in mammalian cell nucleoids.
    Pommier Y, Mattern MR, Schwartz RE, Zwelling LA.
    Biochemistry; 1984 Jun 19; 23(13):2922-7. PubMed ID: 6547848
    [Abstract] [Full Text] [Related]

  • 16. Mechanism of antitumor drug action: poisoning of mammalian DNA topoisomerase II on DNA by 4'-(9-acridinylamino)-methanesulfon-m-anisidide.
    Nelson EM, Tewey KM, Liu LF.
    Proc Natl Acad Sci U S A; 1984 Mar 19; 81(5):1361-5. PubMed ID: 6324188
    [Abstract] [Full Text] [Related]

  • 17. Enhancement of the DNA breakage and cytotoxic effects of intercalating agents by treatment with sublethal doses of 1-beta-D-arabinofuranosylcytosine or hydroxyurea in L1210 cells.
    Minford J, Kerrigan D, Nichols M, Shackney S, Zwelling LA.
    Cancer Res; 1984 Dec 19; 44(12 Pt 1):5583-93. PubMed ID: 6208999
    [Abstract] [Full Text] [Related]

  • 18. Proliferation dependence of topoisomerase II mediated drug action.
    Sullivan DM, Glisson BS, Hodges PK, Smallwood-Kentro S, Ross WE.
    Biochemistry; 1986 Apr 22; 25(8):2248-56. PubMed ID: 3011082
    [Abstract] [Full Text] [Related]

  • 19. Interrelationship between affinity for DNA, cytotoxicity and induction of DNA-breaks in cultured L1210 cells for two series of tricyclic intercalators. Simplified analogues of ellipticine derivatives.
    Pierson V, Pierre A, de Cointet P, Nguyen CH, Bisagni E, Gros P.
    Biochem Pharmacol; 1989 May 01; 38(9):1395-406. PubMed ID: 2719718
    [Abstract] [Full Text] [Related]

  • 20. Intercalator-induced, topoisomerase II-mediated DNA cleavage and its modification by antineoplastic antimetabolites.
    Zwelling LA, Silberman L, Estey E.
    Int J Radiat Oncol Biol Phys; 1986 Jul 01; 12(7):1041-7. PubMed ID: 2427489
    [Abstract] [Full Text] [Related]

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