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Journal Abstract Search

160 related items for PubMed ID: 30025350

  • 1. Design, synthesis and screening of 1, 2, 4-triazinone derivatives as potential antitumor agents with apoptosis inducing activity on MCF-7 breast cancer cell line.
    Zaki I, Abdelhameid MK, El-Deen IM, Abdel Wahab AHA, Ashmawy AM, Mohamed KO.
    Eur J Med Chem; 2018 Aug 05; 156():563-579. PubMed ID: 30025350
    [Abstract] [Full Text] [Related]

  • 2. Design, synthesis, and cytotoxicity screening of 5-aryl-3-(2-(pyrrolyl) thiophenyl)-1, 2, 4-oxadiazoles as potential antitumor molecules on breast cancer MCF-7 cells.
    Abd El Hameid MK, Mohammed MR.
    Bioorg Chem; 2019 May 05; 86():609-623. PubMed ID: 30807934
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents.
    Wang ZZ, Sun WX, Wang X, Zhang YH, Qiu HY, Qi JL, Pang YJ, Lu GH, Wang XM, Yu FG, Yang YH.
    Chem Biol Drug Des; 2017 Aug 05; 90(2):236-243. PubMed ID: 28079286
    [Abstract] [Full Text] [Related]

  • 4. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE, Gedawy EM.
    Eur J Med Chem; 2018 Apr 25; 150():403-418. PubMed ID: 29547830
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis and biological evaluation of chromenopyrimidines as potential cytotoxic agents.
    El-Bakhshawangy NM, El-Nassan HB, Kassab AE, Taher AT.
    Future Med Chem; 2018 Jun 01; 10(12):1465-1481. PubMed ID: 29779400
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
    [Abstract] [Full Text] [Related]

  • 7. Synthesis of a terphenyl substituted 4-aza-2,3-didehydropodophyllotoxin analogues as inhibitors of tubulin polymerization and apoptosis inducers.
    Kamal A, Tamboli JR, Nayak VL, Adil SF, Vishnuvardhan MV, Ramakrishna S.
    Bioorg Med Chem; 2014 May 01; 22(9):2714-23. PubMed ID: 24721832
    [Abstract] [Full Text] [Related]

  • 8. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
    Zhao W, Chen L, Li HM, Wang DJ, Li DS, Chen T, Yuan ZP, Tang YJ.
    Bioorg Med Chem; 2014 Jun 01; 22(11):2998-3007. PubMed ID: 24775914
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells.
    Batran RZ, Kassem AF, Abbas EMH, Elseginy SA, Mounier MM.
    Bioorg Med Chem; 2018 Jul 23; 26(12):3474-3490. PubMed ID: 29793751
    [Abstract] [Full Text] [Related]

  • 10. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG, Bonam SR, Reddy TS, Akunuri R, Naidu VGM, Nayak VL, Bhargava SK, Kumar HMS, Srihari P, Kamal A.
    Eur J Med Chem; 2018 Jan 20; 144():595-611. PubMed ID: 29289884
    [Abstract] [Full Text] [Related]

  • 11. Investigation of podophyllotoxin esters as potential anticancer agents: synthesis, biological studies and tubulin inhibition properties.
    Shareef MA, Duscharla D, Ramasatyaveni G, Dhoke NR, Das A, Ummanni R, Srivastava AK.
    Eur J Med Chem; 2015 Jan 07; 89():128-37. PubMed ID: 25462233
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis, and biological evaluation of novel combretastatin A-4 thio derivatives as microtubule targeting agents.
    Stefański T, Mikstacka R, Kurczab R, Dutkiewicz Z, Kucińska M, Murias M, Zielińska-Przyjemska M, Cichocki M, Teubert A, Kaczmarek M, Hogendorf A, Sobiak S.
    Eur J Med Chem; 2018 Jan 20; 144():797-816. PubMed ID: 29291446
    [Abstract] [Full Text] [Related]

  • 13. Design and synthesis of silicon-containing tubulin polymerization inhibitors: replacement of the ethylene moiety of combretastatin A-4 with a silicon linker.
    Nakamura M, Kajita D, Matsumoto Y, Hashimoto Y.
    Bioorg Med Chem; 2013 Dec 01; 21(23):7381-91. PubMed ID: 24139940
    [Abstract] [Full Text] [Related]

  • 14. Scaffold overlay of flavonoid-inspired molecules: Discovery of 2,3-diaryl-pyridopyrimidin-4-imine/ones as dual hTopo-II and tubulin targeting anticancer agents.
    Saini M, Paul S, Acharya A, Acharya SS, Kundu CN, Guchhait SK.
    Bioorg Chem; 2024 Nov 01; 152():107738. PubMed ID: 39182257
    [Abstract] [Full Text] [Related]

  • 15. Design and synthesis of thienopyrimidine urea derivatives with potential cytotoxic and pro-apoptotic activity against breast cancer cell line MCF-7.
    Abdelhaleem EF, Abdelhameid MK, Kassab AE, Kandeel MM.
    Eur J Med Chem; 2018 Jan 01; 143():1807-1825. PubMed ID: 29133058
    [Abstract] [Full Text] [Related]

  • 16. Design, Synthesis and Screening of 4,6-Diaryl Pyridine and Pyrimidine Derivatives as Potential Cytotoxic Molecules.
    Abd Elhameid MK, Ryad N, Al-Shorbagy MY, Mohammed MR, Ismail MM, El Meligie S.
    Chem Pharm Bull (Tokyo); 2018 Oct 01; 66(10):939-952. PubMed ID: 30111667
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and screening of benzimidazole containing compounds with methoxylated aryl radicals as cytotoxic molecules on (HCT-116) colon cancer cells.
    Noha RM, Abdelhameid MK, Ismail MM, Mohammed MR, Salwa E.
    Eur J Med Chem; 2021 Jan 01; 209():112870. PubMed ID: 33158579
    [Abstract] [Full Text] [Related]

  • 18. Methyl 5-[(1H-indol-3-yl)selanyl]-1H-benzoimidazol-2-ylcarbamate (M-24), a novel tubulin inhibitor, causes G2/M arrest and cell apoptosis by disrupting tubulin polymerization in human cervical and breast cancer cells.
    Zuo D, Jiang X, Han M, Shen J, Lang B, Guan Q, Bai Z, Han C, Li Z, Zhang W, Wu Y.
    Toxicol In Vitro; 2017 Aug 01; 42():139-149. PubMed ID: 28412508
    [Abstract] [Full Text] [Related]

  • 19. Design, Synthesis, and Screening of 5-Aryl-3-(2-(pyrrolyl)thiophenyl)-1,2,4-oxadiazoles as Potential Antitumor Molecules on Breast Cancer MCF-7 Cell Line.
    Abd El Hameid MK.
    Chem Pharm Bull (Tokyo); 2018 Dec 01; 66(12):1181-1195. PubMed ID: 30298827
    [Abstract] [Full Text] [Related]

  • 20. New promising levofloxacin derivatives: Design, synthesis, cytotoxic activity screening, Topo2β polymerase inhibition assay, cell cycle apoptosis profile analysis.
    El-Malah A, Youssef A, Ismail M, Kamel M, Mahmoud Z.
    Bioorg Chem; 2021 Aug 01; 113():105029. PubMed ID: 34091290
    [Abstract] [Full Text] [Related]

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